{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:28:12Z","timestamp":1787498892592,"version":"build-2736575974"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T00:00:00Z","timestamp":1688342400000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pheochromocytomas (PHEOs) are a group of tumours that leads to multiple symptoms and can induce hypercoagulability and promote thrombosis. Pheochromocytomas may also present without elevated serum and urinary markers. We aimed to provide tips and tricks for the diagnostic and therapeutic management of an unusual case of PHEOs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>Thirty-four-year-old woman with the unremarkable medical history presented with epigastric pain and dyspnoea. Electrocardiogram showed ST-segment elevation in the inferior limb leads. She underwent an emergency coronary angiogram, which showed a high thrombus burden in the distal right coronary artery. A subsequent echocardiogram demonstrated a 31 \u00d7 33\u2005mm right atrial mass adhering to the inferior vena cava and abdominal computed tomography (CT) scan revealed a 113 \u00d7 85\u2005mm necrotic mass in the left adrenal bed, with tumour thrombus extending proximally to the confluence of hepatic veins immediately inferior to the right atrium and distally to iliac vein bifurcation. Blood parameters, thrombophilia panel, vanillylmandelic acid, 5 hydroxy indole acetic acid, and homovanillic acid levels were normal. Tissue sampling confirmed the diagnosis of PHEOs. The surgical procedure was not planned due to the presence of metastatic foci on imaging, including positron emission tomography (PET)\u2013CT. Anticoagulation with rivaroxaban and treatment with 177Lu-DOTATATE-based peptide receptor radionuclide therapy (PRRT) was initiated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The coexistence of arterial and venous thrombosis is extremely rare in patients with PHEOs. Multidisciplinary approaches are required for the care of such patients. Catecholamines likely contributed to the development of thrombosis in our patient. Early recognition of PHEOs is the key point to ameliorate clinical outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytad249","type":"journal-article","created":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T13:59:04Z","timestamp":1687960744000},"source":"Crossref","is-referenced-by-count":4,"title":["Unusual case report of malignant pheochromocytoma presenting with STEMI"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9049-7123","authenticated-orcid":false,"given":"Muhammed","family":"Demir","sequence":"first","affiliation":[{"name":"Department of Cardiology, Dicle University School of Medicine , Fiskaya Street, Diyarbakir 21280 , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2243-6190","authenticated-orcid":false,"given":"Mehmet","family":"\u00d6zbek","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dicle University School of Medicine , Fiskaya Street, Diyarbakir 21280 , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8470-1928","authenticated-orcid":false,"given":"Tuncay","family":"G\u00fczel","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Health Science University, Gazi Ya\u015fargil Training and Research Hospital, Elazig Street 10. Km \u00dc\u00e7kuyular , Kayap\u0131nar\/Diyarbak\u0131r 21070 , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0505-9784","authenticated-orcid":false,"given":"Adem","family":"Aktan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Mardin Training and Research Hospital, Nur District, Vali Ozan Boulevard , Artuklu\/Mardin 47100 , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,7,3]]},"reference":[{"key":"2023072711561798000_ytad249-B1","doi-asserted-by":"crossref","first-page":"315","DOI":"10.7326\/0003-4819-134-4-200102200-00016","article-title":"Recent advances in genetics, diagnosis, localization, and treatment of PHEOs","volume":"134","author":"Pacak","year":"2001","journal-title":"Ann Intern Med"},{"key":"2023072711561798000_ytad249-B2","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1097\/00005792-199101000-00004","article-title":"A simplified diagnostic approach to PHEOs. 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