{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T21:12:38Z","timestamp":1785273158025,"version":"3.55.0"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,3,4]],"date-time":"2024-03-04T00:00:00Z","timestamp":1709510400000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Despite modern techniques for ablation of ventricular tachycardia (VT), the procedure faces challenges such as deep intramural substrates or inaccessibility of the pericardial space. We aim to present a case of successful surgical treatment of a patient with drug-refractory VT, an apical aneurysm, large left ventricular (LV) thrombus, and recurrent implantable cardioverter defibrillator (ICD) shocks following failed epicardial catheter ablation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 67-year-old male with a history of ischaemic cardiomyopathy was brought to the emergency room after a syncope because of VT. The VT was terminated by an external cardioversion prior to admission. The ICD interrogation showed an episode of sustained monomorphic VT with eight appropriate but mostly ineffective ICD shocks. An echocardiogram revealed an apical aneurysm with a thrombus. Anticoagulation and antiarrhythmic drug therapy were initiated. Days later, the patient suffered recurrent episodes of sustained VTs, refractory to pharmacological therapy, and epicardial ablation; therefore, following aneurysmectomy and thrombus removal, a reconstruction of the LV and surgical endocardial cryoablation were performed. In addition, ICD extraction was done due to recurrent bacteraemia with Staphylococcus aureus. A subcutaneous ICD was later implanted. After surgery, the patient remained free of any VT episodes during 44 months of follow-up.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Combined surgical ventricular reconstruction and intraoperative cryoablation may be considered as an alternative, highly effective therapy in patients with drug-refractory VTs in the setting of a LV thrombus.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytae113","type":"journal-article","created":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T00:37:07Z","timestamp":1709599027000},"source":"Crossref","is-referenced-by-count":2,"title":["Surgical ventricular reconstruction and intraoperative cryoablation in a patient with drug-refractory ventricular tachycardia and left ventricular thrombus: a case report"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0429-6235","authenticated-orcid":false,"given":"Maryuri Delgado","family":"Lopez","sequence":"first","affiliation":[{"name":"Department of Rhythmology, University Heart Center L\u00fcbeck, University Hospital Schleswig-Holstein (UKSH), Campus L\u00fcbeck , Ratzeburger Allee 160 , L\u00fcbeck 23538, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8386-9750","authenticated-orcid":false,"given":"Julia","family":"Vogler","sequence":"additional","affiliation":[{"name":"Department of Rhythmology, University Heart Center L\u00fcbeck, University Hospital Schleswig-Holstein (UKSH), Campus L\u00fcbeck , Ratzeburger Allee 160 , L\u00fcbeck 23538, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anas","family":"Aboud","sequence":"additional","affiliation":[{"name":"Department of Cardiac and Thoracic Vascular Surgery, University of Schleswig-Holstein, Campus L\u00fcbeck , L\u00fcbeck , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian-Hendrik","family":"Heeger","sequence":"additional","affiliation":[{"name":"Department of Rhythmology, University Heart Center L\u00fcbeck, University Hospital Schleswig-Holstein (UKSH), Campus L\u00fcbeck , Ratzeburger Allee 160 , L\u00fcbeck 23538, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland Richard","family":"Tilz","sequence":"additional","affiliation":[{"name":"Department of Rhythmology, University Heart Center L\u00fcbeck, University Hospital Schleswig-Holstein (UKSH), Campus L\u00fcbeck , Ratzeburger Allee 160 , L\u00fcbeck 23538, 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scylla and charybdis?","volume":"27","author":"Kumar","year":"2016","journal-title":"J Cardiovasc Electrophysiol"},{"key":"2024032712231687800_ytae113-B4","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s11748-017-0853-2","article-title":"Surgical treatment for endocardial radiofrequency ablation-resistant sustained monomorphic ventricular tachycardia with mural thrombus including dense calcification in the left ventricle","volume":"66","author":"Higuchi","year":"2018","journal-title":"Gen Thorac Cardiovasc Surg"},{"key":"2024032712231687800_ytae113-B5","doi-asserted-by":"crossref","first-page":"e155","DOI":"10.1016\/j.hrthm.2019.03.014","article-title":"2019 HRS\/EHRA\/APHRS\/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias: executive summary","volume":"17","author":"Cronin","year":"2020","journal-title":"Heart 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