{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:49:47Z","timestamp":1753876187796,"version":"3.41.2"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Left ventricular thrombus (LVT) formation is a serious complication of acute myocardial infarction (AMI) requiring complicated management strategies and collaboration among cardiologists, cardiovascular surgeons, and neurosurgeons.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>We present the case of an 83-year-old female patient with AMI. Emergency coronary angiography revealed subtotal occlusion of the proximal left anterior descending artery, and the patient was successfully treated with a drug-eluting stent. The following day, she suddenly developed loss of consciousness, global aphasia, and right hemiplegia. Brain magnetic resonance imaging revealed acute ischaemic cerebral infarction caused by multiple mobile LVT, as demonstrated by echocardiography. After a heart\u2013brain team discussion, we decided to perform percutaneous mechanical thrombectomy. Successful recanalization was achieved with mechanical thrombectomy 2\u2005h after presentation, which resulted in significant neurological recovery. Immediately after the thrombectomy, she was transferred to a cardiovascular surgery centre for surgical removal of multiple LV apical thrombi. Two weeks after the operation, the patient was discharged with the recovery of LV systolic function.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Although AMI complicated by acute stroke caused by LVT remains a clinical challenge, a multidisciplinary approach is critically important for optimal care. Based on an urgent team discussion, we decided to perform endovascular thrombectomy for ischaemic stroke, followed by surgical removal of the LVT, requiring patient transportation to the cardiovascular surgery centre. Given that the heart and brain team-based approach remains confined to large, specialized centres, it might be beneficial to establish a community-based integrated heart\u2013brain team that can address the growing needs of complex patients.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytae193","type":"journal-article","created":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T17:39:55Z","timestamp":1713202795000},"source":"Crossref","is-referenced-by-count":0,"title":["A case report of concurrent management of acute myocardial infarction complicated by left ventricular thrombus and ischaemic stroke"],"prefix":"10.1093","volume":"8","author":[{"given":"Yuka","family":"Kodama","sequence":"first","affiliation":[{"name":"Department of Cardiology, Izumi City General Hospital , 4-5-1 Wake-cho, Izumi 594-0073 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6160-1920","authenticated-orcid":false,"given":"Kenji","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Izumi City General Hospital , 4-5-1 Wake-cho, Izumi 594-0073 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisashi","family":"Kubota","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Kubota Clinic Neurosurgery , Izumi , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Onichi","family":"Furuya","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Kishiwada Tokushukai Hospital , Kishiwada , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshio","family":"Kawase","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Izumi City General Hospital , 4-5-1 Wake-cho, Izumi 594-0073 , 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heparin: a statement for healthcare professionals from the American Heart Association","volume":"103","author":"Hirsh","year":"2001","journal-title":"Circulation"},{"key":"2024043013574542200_ytae193-B7","doi-asserted-by":"crossref","first-page":"e205","DOI":"10.1161\/CIR.0000000000001092","article-title":"Management of patients at risk for and with left ventricular thrombus: a scientific statement from the American Heart Association","volume":"146","author":"Levine","year":"2022","journal-title":"Circulation"},{"key":"2024043013574542200_ytae193-B8","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1093\/ehjcvp\/pvaa066","article-title":"Left ventricular thrombosis: new perspectives on an old problem","volume":"7","author":"Massussi","year":"2021","journal-title":"Eur Heart J Cardiovasc Pharmacother"},{"key":"2024043013574542200_ytae193-B9","doi-asserted-by":"crossref","first-page":"S307","DOI":"10.1016\/j.carrev.2022.08.036","article-title":"Surgical transmitral thrombectomy to prevent recurrent stroke in acute myocardial infarction","volume":"53S","author":"Hasun","year":"2023","journal-title":"Cardiovasc Revasc Med"},{"key":"2024043013574542200_ytae193-B10","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1007\/s11239-019-01829-6","article-title":"Characterisation of acute ischemic stroke in patients with left ventricular thrombi after myocardial infarction","volume":"48","author":"Leow","year":"2019","journal-title":"J Thromb Thrombolysis"},{"key":"2024043013574542200_ytae193-B11","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1253\/circj.CJ-19-1109","article-title":"JCS 2020 guideline focused update on antithrombotic therapy in patients with coronary artery disease","volume":"84","author":"Nakamura","year":"2020","journal-title":"Circ J"},{"key":"2024043013574542200_ytae193-B12","doi-asserted-by":"crossref","first-page":"3720","DOI":"10.1093\/eurheartj\/ehad191","article-title":"2023 ESC guidelines for the management of acute 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