{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:50:27Z","timestamp":1753876227057,"version":"3.41.2"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T00:00:00Z","timestamp":1716508800000},"content-version":"vor","delay-in-days":23,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,2]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Kawasaki disease (KD) is a paediatric multi-system vasculitis. Mainly, the coronary arteries become affected due to acute inflammation and formation of coronary artery aneurysms (CAAs) may occur. As the size of the CAA increases, so does the risk of clinical complications and serious cardiac outcomes. These patients may experience life-threatening thrombotic coronary artery occlusion and myocardial ischaemia unless antiplatelet and anticoagulation therapy is not initiated in a timely manner.1<\/jats:p>\n <\/jats:sec>\n \n Case summary<\/jats:title>\n This case report presents a 12-year-old patient with KD who developed CAAs in two coronary arteries despite initial administration of intravenous immunoglobulins and acetylsalicylic acid, followed by extensive thrombosis of both coronary arteries, although antithrombotic therapy was started after the diagnosis of CAAs.<\/jats:p>\n <\/jats:sec>\n \n Discussion<\/jats:title>\n Our case is notable because of the severity of the clinical manifestation despite the administration of antiplatelet agents and anticoagulants. It could be speculated that the development of coronary thrombosis in this case might be strongly correlated with the late initiation of oral anticoagulation. The high-quality images of the affected coronary arteries in such a young patient could be of educational value.<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytae250","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T07:33:39Z","timestamp":1716536019000},"source":"Crossref","is-referenced-by-count":0,"title":["Extensive coronary artery thrombosis in a paediatric patient with Kawasaki disease: a case report"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8090-2044","authenticated-orcid":false,"given":"Tilbe","family":"Kasap","sequence":"first","affiliation":[{"name":"Department of Congenital Heart Disease and Pediatric Cardiology, University Hospital Schleswig-Holstein , Arnold-Heller-Str. 3, 24105 Kiel , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inga","family":"Voges","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein , Arnold-Heller-Str. 3, 24105 Kiel , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katy","family":"Rinne","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein , Arnold-Heller-Str. 3, 24105 Kiel , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7138-7415","authenticated-orcid":false,"given":"Patrick","family":"Langguth","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Disease and Pediatric Cardiology, University Hospital Schleswig-Holstein , Arnold-Heller-Str. 3, 24105 Kiel , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,5,24]]},"reference":[{"key":"2024053017324269300_ytae250-B1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/s12887-022-03151-2","article-title":"Myocardial infarction due to thrombotic occlusion despite anticoagulation in Kawasaki disease\u2014a case report","volume":"22","author":"van Stijn","year":"2022","journal-title":"BMC Pediatr"},{"key":"2024053017324269300_ytae250-B2","first-page":"178","article-title":"Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children [in Japanese]","volume":"16","author":"Kawasaki","year":"1967","journal-title":"Arerugi"},{"key":"2024053017324269300_ytae250-B3","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1016\/j.jacc.2015.12.073","article-title":"Kawasaki disease","volume":"67","author":"Newburger","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"2024053017324269300_ytae250-B4","first-page":"e927","article-title":"Diagnosis, treatment, and long-term management of Kawasaki disease: a scientific statement for health professionals from the American Heart Association","volume":"135","author":"Crindle","year":"2017","journal-title":"Circulation"},{"key":"2024053017324269300_ytae250-B5","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1186\/1756-0500-6-500","article-title":"Kawasaki disease in a 3-month-old patient: a case report","volume":"6","author":"Leonardi","year":"2013","journal-title":"BMC Res Notes"},{"key":"2024053017324269300_ytae250-B6","doi-asserted-by":"crossref","first-page":"2606","DOI":"10.1161\/CIRCULATIONAHA.105.592865","article-title":"Prediction of intravenous immunoglobulin unresponsiveness in patients with Kawasaki disease","volume":"113","author":"Kobayashi","year":"2006","journal-title":"Circulation"}],"container-title":["European Heart Journal - 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