{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:49:14Z","timestamp":1753876154550,"version":"3.41.2"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T00:00:00Z","timestamp":1719360000000},"content-version":"vor","delay-in-days":25,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Primary pericardial sarcomas are extremely rare malignancies. In this case of primary pericardial synovial sarcoma, we discuss the initial steps to work-up pericardial effusions and review features that warrant more detailed investigation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 29-year-old male with no relevant past medical history presents with a few weeks of fatigue, dyspnoea, orthopnoea, leg swelling, and back pain. Transthoracic echocardiogram revealed pericardial effusion for which pericardiocentesis and drain placement were done. He was discharged with a diagnosis of post-viral pericarditis. He returned 5 months later with worsening symptoms. Advanced imaging with cardiac magnetic resonance imaging (CMR) showed heterogeneous pericardial mass later revealed to be a high-grade synovial sarcoma on biopsy. The patient was started on a doxorubicin-based chemotherapy regimen, but due to kidney dysfunction and multi-organ failure, he was transitioned to palliative care measures.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Transthoracic echocardiogram and computed tomography are often the initial tests of choice for pericardial effusions with pericardiocentesis recommended for effusions with tamponade physiology, for moderate-to-large effusions, or if there is concern for infection\/neoplasm. Due to improved tissue characterization and spatial resolution, CMR and positron emission tomography should also be considered for atypical or recurrent pericardial effusions to assess for less common aetiologies such as malignancy.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytae284","type":"journal-article","created":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T17:30:12Z","timestamp":1719423012000},"source":"Crossref","is-referenced-by-count":2,"title":["A case report of primary pericardial sarcoma"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1657-9836","authenticated-orcid":false,"given":"Abhijit","family":"Ravindran","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine, University of Virginia Health System , Charlottesville, VA 22902 , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew S","family":"Miller","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, University of Virginia Health System , Charlottesville, VA 22902 , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Ayers","sequence":"additional","affiliation":[{"name":"Division of Hematology & Oncology, University of Virginia Health System , Charlottesville, VA 22902 , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence","family":"Gimple","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, University of Virginia Health System , Charlottesville, VA 22902 , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Ayers","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, University of Virginia Health System , Charlottesville, VA 22902 , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,6,26]]},"reference":[{"key":"2024062617295994200_ytae284-B1","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1093\/eurheartj\/ehv318","article-title":"2015 ESC guidelines for the diagnosis and management of pericardial diseases: the task force for the diagnosis and management of pericardial diseases of the European Society of Cardiology (ESC) Endorsed by: the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"36","author":"Adler","year":"2015","journal-title":"Eur Heart J"},{"author":"Zhou","key":"2024062617295994200_ytae284-B2"},{"key":"2024062617295994200_ytae284-B3","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1093\/ehjci\/jead221","article-title":"How to evaluate cardiac masses by cardiovascular magnetic resonance parametric mapping?","volume":"24","author":"Bonnes","year":"2023","journal-title":"Eur Heart J\u2014Cardiovasc Imaging"},{"key":"2024062617295994200_ytae284-B4","first-page":"1027","article-title":"Tumors of the heart. A 20-year experience with a review of 12,485 consecutive autopsies","volume":"117","author":"Lam","year":"1993","journal-title":"Arch Pathol Lab Med"},{"key":"2024062617295994200_ytae284-B5","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1111\/j.1540-8191.2009.00827.x","article-title":"Pericardial synovial sarcoma","volume":"24","author":"Moorjani","year":"2009","journal-title":"J Card Surg"},{"key":"2024062617295994200_ytae284-B6","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S1470-2045(05)70093-0","article-title":"Cardiac tumours: diagnosis and management","volume":"6","author":"Butany","year":"2005","journal-title":"Lancet Oncol"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/8\/6\/ytae284\/58341594\/ytae284.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/8\/6\/ytae284\/58341594\/ytae284.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T17:30:16Z","timestamp":1719423016000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytae284\/7699769"}},"subtitle":[],"editor":[{"given":"Jamal Nasir","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Niraj Nirmal","family":"Pandey","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Saadia","family":"Aslam","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Tom","family":"Wardill","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2024,6,1]]},"references-count":6,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytae284","relation":{},"ISSN":["2514-2119"],"issn-type":[{"type":"electronic","value":"2514-2119"}],"subject":[],"published-other":{"date-parts":[[2024,6]]},"published":{"date-parts":[[2024,6,1]]},"article-number":"ytae284"}}