{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:29:23Z","timestamp":1790116163004,"version":"4.0.1"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T00:00:00Z","timestamp":1719187200000},"content-version":"vor","delay-in-days":23,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"International Research"},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico-Brasil","doi-asserted-by":"publisher","award":["88887.716769\/2022-00"],"award-info":[{"award-number":["88887.716769\/2022-00"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001316","name":"Abbott","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001316","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008497","name":"Boston Scientific","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005035","name":"Biotronik","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005035","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006520","name":"Edwards Lifesciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006520","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"name":"PulseCath BV"},{"DOI":"10.13039\/100020297","name":"Abiomed","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020297","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002973","name":"Daiichi Sankyo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002973","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019998","name":"JenaValve","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019998","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Left ventricular assist devices (LVADs) are increasingly utilized in cardiogenic shock and high-risk percutaneous coronary interventions (PCIs). These devices aspirate and expel blood from the left ventricle (LV) into the aorta, consequently reducing left ventricular end-diastolic pressure (LVEDP). We report a case of unexpected LVEDP rise under LV-to-aorta LVAD in the context of transcatheter aortic valve implantation (TAVI) and concomitant multi-vessel PCI.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A patient with acute heart failure, severely depressed systolic LV function, severe aortic stenosis, and multi-vessel coronary artery disease underwent TAVI and concomitant PCI under pulsatile LVAD. Notably, the patient experienced unexpected shortness of breath and elevated LVEDP while under LVAD, which normalized immediately upon LVAD removal.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Pulsatile LVAD enhances cardiac output by providing pulsatile support through a percutaneous bi-directional flow catheter. Despite expectations of reduced LVEDP and improved myocardial oxygen supply under LVAD support, we observed high LVEDP and clinical complaints of shortness of breath following TAVI and multi-vessel PCI. This case illustrates that an LVAD across the aortic valve may immobilize aortic leaflets and generate acute aortic regurgitation.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytae291","type":"journal-article","created":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T16:11:38Z","timestamp":1719245498000},"source":"Crossref","is-referenced-by-count":2,"title":["Case report of increased left ventricular end-diastolic pressure with pulsatile left ventricular assist device"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5030-6727","authenticated-orcid":false,"given":"Mauricio Felippi","family":"de S\u00e1 Marchi","sequence":"first","affiliation":[{"name":"Department of Cardiology, Thoraxcenter, Erasmus University Medical Center , Rotterdam , The Netherlands"},{"name":"Department of Interventional Cardiology, Heart Institute (InCor), Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9822-7833","authenticated-orcid":false,"given":"Sarah","family":"Verhemel","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Thoraxcenter, Erasmus University Medical Center , Rotterdam , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3047-6707","authenticated-orcid":false,"given":"Rutger-Jan","family":"Nuis","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Thoraxcenter, Erasmus University Medical Center , Rotterdam , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2732-1205","authenticated-orcid":false,"given":"Nicolas M","family":"Van Mieghem","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Thoraxcenter, Erasmus University Medical Center , Rotterdam , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,6,24]]},"reference":[{"key":"2024062714254287900_ytae291-B1","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/s41569-022-00796-5","article-title":"Temporary mechanical circulatory support devices: practical considerations for all stakeholders","volume":"20","author":"Salter","year":"2023","journal-title":"Nat Rev Cardiol"},{"key":"2024062714254287900_ytae291-B2","doi-asserted-by":"crossref","first-page":"e21","DOI":"10.1016\/j.jacc.2021.09.006","article-title":"2021 ACC\/AHA\/SCAI guideline for coronary artery revascularization: a report of the American College of Cardiology\/American Heart Association joint committee on clinical practice Guidelines","volume":"79","author":"Lawton","year":"2022","journal-title":"J Am Coll Cardiol"},{"key":"2024062714254287900_ytae291-B3"},{"key":"2024062714254287900_ytae291-B4","doi-asserted-by":"crossref","first-page":"835","DOI":"10.4244\/EIJV11I7A168","article-title":"The PulseCath iVAC 2L left ventricular assist device: conversion to a percutaneous transfemoral approach","volume":"11","author":"Van Mieghem","year":"2015","journal-title":"EuroIntervention"},{"key":"2024062714254287900_ytae291-B5","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.4244\/EIJ-D-16-00371","article-title":"Pulsatile iVAC 2L circulatory support in high-risk percutaneous coronary intervention","volume":"12","author":"den Uil","year":"2017","journal-title":"EuroIntervention"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/advance-article-pdf\/doi\/10.1093\/ehjcr\/ytae291\/58318624\/ytae291.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/8\/6\/ytae291\/58346581\/ytae291.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/8\/6\/ytae291\/58346581\/ytae291.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T17:21:18Z","timestamp":1719508878000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytae291\/7697915"}},"subtitle":[],"editor":[{"given":"Julio","family":"Echarte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Duygu","family":"Kocyigit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"A Shaheer","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Nicolo","family":"Sisti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,6,1]]},"references-count":5,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytae291","relation":{},"ISSN":["2514-2119"],"issn-type":[{"value":"2514-2119","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,6]]},"published":{"date-parts":[[2024,6,1]]},"article-number":"ytae291"}}