{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T22:06:18Z","timestamp":1755036378318,"version":"3.41.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T00:00:00Z","timestamp":1721692800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Left ventricular (LV) unloading prior to primary angioplasty in patients experiencing acute myocardial infarction holds promise for mitigating reperfusion injury and minimizing infarct size.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>This report delves into the utilization of left atrial venoarterial extracorporeal membrane oxygenation (LAVA-ECMO) as a pre-percutaneous transluminal coronary angioplasty (PTCA) intervention strategy aimed at augmenting circulatory support while unloading the LV. Three cases of patients with ST elevation myocardial infarction involving the left ascending coronary artery who underwent LAVA-ECMO before primary PTCA are presented. Each patient maintained robust LV systolic function following weaning from ECMO support.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>These cases underscore the potential benefits of mechanical LV unloading prior to revascularization in reducing infarct size and mitigating the risk of post-myocardial infarction heart failure.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytae362","type":"journal-article","created":{"date-parts":[[2024,7,20]],"date-time":"2024-07-20T02:14:43Z","timestamp":1721441683000},"source":"Crossref","is-referenced-by-count":1,"title":["Utilizing left atrial venoarterial extracorporeal membrane oxygenation to unload the left ventricle prior to angioplasty in acute myocardial infarction: a case series"],"prefix":"10.1093","volume":"8","author":[{"given":"Hung-Chang","family":"Jong","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine, Shuang Ho Hospital , No. 291, Zhongzheng Rd., Zhonghe District, New Taipei City 235041 , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kexuan","family":"Ngoh","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine, Shuang Ho Hospital , No. 291, Zhongzheng Rd., Zhonghe District, New Taipei City 235041 , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Kai","family":"Lin","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine, Shuang Ho Hospital , No. 291, Zhongzheng Rd., Zhonghe District, New Taipei City 235041 , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsu-Ting","family":"Tu","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine, Shuang Ho Hospital , No. 291, Zhongzheng Rd., Zhonghe District, New Taipei City 235041 , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0124-9524","authenticated-orcid":false,"given":"Ta-jung","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine, Shuang Ho Hospital , No. 291, Zhongzheng Rd., Zhonghe District, New Taipei City 235041 , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,7,23]]},"reference":[{"key":"2024080616002444600_ytae362-B1","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.jacc.2020.06.031","article-title":"Transvalvular ventricular unloading before reperfusion in acute myocardial infarction","volume":"76","author":"Swain","year":"2020","journal-title":"J Am Coll 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functional recovery after acute myocardial infarction","volume":"72","author":"Esposito","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"2024080616002444600_ytae362-B8","doi-asserted-by":"crossref","first-page":"e004397","DOI":"10.1161\/CIRCHEARTFAILURE.117.004397","article-title":"Left ventricular mechanical unloading by total support of Impella in myocardial infarction reduces infarct size, preserves left ventricular function, and prevents subsequent heart failure in dogs","volume":"11","author":"Saku","year":"2018","journal-title":"Circ Heart Fail"},{"key":"2024080616002444600_ytae362-B9","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1161\/CIRCULATIONAHA.118.038269","article-title":"Unloading the left ventricle before reperfusion in patients with anterior ST-segment-elevation myocardial infarction","volume":"139","author":"Kapur","year":"2019","journal-title":"Circulation"},{"key":"2024080616002444600_ytae362-B10","doi-asserted-by":"crossref","first-page":"549","DOI":"10.2217\/fca-2021-0006","article-title":"Door-to-unload: left ventricular unloading before reperfusion in ST-elevation myocardial infarction","volume":"17","author":"Parikh","year":"2021","journal-title":"Future Cardiol"}],"container-title":["European Heart Journal - Case 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