{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:49:22Z","timestamp":1753876162223,"version":"3.41.2"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T00:00:00Z","timestamp":1725580800000},"content-version":"vor","delay-in-days":5,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Infective endocarditis (IE) predominantly involves the cardiac valves. Timely diagnosis and initiation of therapy significantly reduce morbidity and mortality. Infective endocarditis presenting as a large left ventricular outflow tract (LVOT) mass is an atypical manifestation that provides significant challenges to the treating team.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 19-year-young male presented with exertional shortness of breath, palpitations, and presyncope for 4 months with constitutional symptoms for the last 6 months. Two-dimensional echocardiogram showed a large LVOT mass arising from the mitral aortic intervalvular fibrosa causing dynamic severe aortic valve obstruction, moderate aortic regurgitation, and severe mitral regurgitation. He was managed on lines of IE and received intravenous antibiotics. In view of worsening heart failure and cardiogenic shock, he underwent mass excision, mechanical aortic valve replacement, and mitral valve repair. Histopathology confirmed it as vegetation. He was discharged and is doing well at 2-month follow-up.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>An atypical presentation of IE as a large LVOT mass was observed in this young male. Sound clinical judgement, judicious use of ancillary imaging, and a multidisciplinary approach ensured timely diagnosis and appropriate treatment. Management included appropriate intravenous antibiotics followed by surgery.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytae387","type":"journal-article","created":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T00:14:26Z","timestamp":1725581666000},"source":"Crossref","is-referenced-by-count":0,"title":["Large left ventricular outflow tract mass in a young patient: uncommon presentation of a common disease! A case report"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2135-1961","authenticated-orcid":false,"given":"Shivam","family":"Goel","sequence":"first","affiliation":[{"name":"Department of Cardiology, All India Institute of Medical Sciences , Room no.11, 7th floor, Cardio-Neuro Centre, AIIMS, New Delhi 110049 , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pradeep","family":"Ramakrishnan","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, All India Institute of Medical Sciences , New Delhi , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sreelal","family":"Variar","sequence":"additional","affiliation":[{"name":"Department of Cardioradiology, All India Institute of Medical Sciences , New Delhi , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudheer Kumar","family":"Arava","sequence":"additional","affiliation":[{"name":"Department of Pathology, All India Institute of Medical Sciences , New Delhi , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3060-5794","authenticated-orcid":false,"given":"Sourabh","family":"Agstam","sequence":"additional","affiliation":[{"name":"Department of Cardiology, All India Institute of Medical Sciences , Room no.11, 7th floor, Cardio-Neuro Centre, AIIMS, New Delhi 110049 , India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,9,6]]},"reference":[{"key":"2024090613141484100_ytae387-B1","doi-asserted-by":"crossref","first-page":"3948","DOI":"10.1093\/eurheartj\/ehad193","article-title":"2023 ESC guidelines for the management of endocarditis","volume":"44","author":"Delgado","year":"2023","journal-title":"Eur Heart J"},{"key":"2024090613141484100_ytae387-B2","first-page":"37","article-title":"Morphological study of the human mitral-aortic intervalvular fibrosa","volume":"22","author":"Sales Cavalcanti","year":"2005","journal-title":"J Morphol Sci"},{"key":"2024090613141484100_ytae387-B3","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1016\/j.amjcard.2006.06.016","article-title":"Periannular complications in infective endocarditis involving native aortic valves","volume":"98","author":"Anguera","year":"2006","journal-title":"Am J Cardiol"},{"key":"2024090613141484100_ytae387-B4","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/j.echo.2010.07.015","article-title":"Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (MAIVF): a comprehensive review","volume":"23","author":"Sudhakar","year":"2010","journal-title":"J Am Soc Echocardiogr"},{"key":"2024090613141484100_ytae387-B5","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1053\/euhj.2001.2811","article-title":"The mitral kissing vegetation","volume":"23","author":"Oakley","year":"2002","journal-title":"Eur Heart J"},{"key":"2024090613141484100_ytae387-B6","doi-asserted-by":"crossref","first-page":"269","DOI":"10.33963\/KP.15254","article-title":"Current challenges in the diagnosis and treatment of cardiac myxoma","volume":"78","author":"Samanidis","year":"2020","journal-title":"Kardiol Pol"},{"key":"2024090613141484100_ytae387-B7","first-page":"241","article-title":"Unusual aspects of cardiac myxoma","volume":"17","author":"Yuan","year":"2017","journal-title":"Anatol J Cardiol"},{"key":"2024090613141484100_ytae387-B8","first-page":"571","article-title":"Infected cardiac myxoma: an updated review","volume":"30","author":"Yuan","year":"2014","journal-title":"Rev Bras Cir Cardiovasc"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/8\/9\/ytae387\/59033366\/ytae387.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/8\/9\/ytae387\/59033366\/ytae387.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T19:16:13Z","timestamp":1725650173000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytae387\/7750319"}},"subtitle":[],"editor":[{"given":"Gavin","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Ciro","family":"Santoro","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Timothy","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Polyvios","family":"Demetriades","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2024,9,1]]},"references-count":8,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytae387","relation":{},"ISSN":["2514-2119"],"issn-type":[{"type":"electronic","value":"2514-2119"}],"subject":[],"published-other":{"date-parts":[[2024,9]]},"published":{"date-parts":[[2024,9,1]]},"article-number":"ytae387"}}