{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T19:56:44Z","timestamp":1789502204477,"version":"build-2803163510"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T00:00:00Z","timestamp":1725408000000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Takayasu arteritis (TAK) is a systemic non-inflammatory vasculitis that primarily affects large- and medium-sized arteries.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>We report the case of a 57-year-old woman with a history of coronary artery bypass grafting (CABG) 7\u2005years prior, who was referred for a stress echo due to chest pain. Transthoracic echocardiography revealed the left ventricle at the upper limits of normal with preserved contractility, as well as circumferential thickening of the aortic root, causing severe aortic regurgitation (AR). Cardiac computed tomography and angiography demonstrated diffuse thickening of the aortic wall from the aortic root to the descending thoracic aorta, extending to the left carotid artery and significant stenosis of the left subclavian artery. Coronary angiography showed severe narrowing of the left main coronary ostium with ostial stenosis and total occlusion of the right coronary and left internal mammary arteries. Magnetic angiography highlighted thickening of the aortic wall, while no active inflammation was detected on positron emission tomography. These findings suggested Takayasu aortitis with chronic inflammation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>In young patients, particularly women, who present with angina and coronary ostial stenosis, Takayasu arteritis should be considered in the differential diagnosis. Aortic regurgitation (AR) is a serious complication, and its surgical management can be challenging.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytae473","type":"journal-article","created":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T23:30:36Z","timestamp":1725492636000},"source":"Crossref","is-referenced-by-count":1,"title":["Severe aortic valve regurgitation in patient with Takayasu arteritis: a case report"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-5040-3073","authenticated-orcid":false,"given":"Vasiliki","family":"Tassi","sequence":"first","affiliation":[{"name":"Department of Cardiology, Evangelismos General Hospital , \u03a5psilantou Str. 45-47, 10676 Athens , Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Tzalas","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Evangelismos General Hospital , \u03a5psilantou Str. 45-47, 10676 Athens , Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elektra","family":"Papadopoulou","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Evangelismos General Hospital , \u03a5psilantou Str. 45-47, 10676 Athens , Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athanasios","family":"Trikas","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Evangelismos General Hospital , \u03a5psilantou Str. 45-47, 10676 Athens , Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,9,4]]},"reference":[{"key":"2024092410071555000_ytae473-B1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/art.37715","article-title":"2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides","volume":"65","author":"Jennette","year":"2013","journal-title":"Arthritis Rheum"},{"key":"2024092410071555000_ytae473-B2","first-page":"e197","article-title":"Epidemiology of Takayasu arteritis","volume":"46","author":"Onen","year":"2017","journal-title":"Presse Med Paris Fr 1983"},{"key":"2024092410071555000_ytae473-B3","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1093\/rheumatology\/key040","article-title":"Takayasu arteritis: advanced understanding is leading to new horizons","volume":"58","author":"Tombetti","year":"2019","journal-title":"Rheumatology"},{"key":"2024092410071555000_ytae473-B4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.vph.2015.11.084","article-title":"Aortitis","volume":"80","author":"Bossone","year":"2016","journal-title":"Vascul Pharmacol"},{"key":"2024092410071555000_ytae473-B5","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1002\/art.41774","article-title":"American College of Rheumatology\/Vasculitis Foundation guideline for the management of giant cell arteritis and Takayasu arteritis","volume":"73","author":"Maz","year":"2021","journal-title":"Arthritis Rheum"},{"key":"2024092410071555000_ytae473-B6","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1136\/annrheumdis-2019-215672","article-title":"2018 update of the EULAR recommendations for the management of large vessel vasculitis","volume":"79","author":"Hellmich","year":"2020","journal-title":"Ann Rheum Dis"},{"key":"2024092410071555000_ytae473-B7","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1002\/art.1780370420","article-title":"Treatment of glucocorticoid resistant or relapsing Takayasu arteritis with methotrexate","volume":"37","author":"Hoffman","year":"1994","journal-title":"Arthritis Rheum"},{"key":"2024092410071555000_ytae473-B8","doi-asserted-by":"crossref","first-page":"103","DOI":"10.7812\/TPP\/21.017","article-title":"Surgical management of aortic regurgitation in Takayasu's arteritis: a systematic review of techniques and outcomes","volume":"26","author":"Fath","year":"2022","journal-title":"Perm J"},{"key":"2024092410071555000_ytae473-B9","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.ijcard.2017.02.041","article-title":"Outcomes of percutaneous coronary intervention and coronary artery bypass grafting in patients with Takayasu arteritis","volume":"241","author":"Yang","year":"2017","journal-title":"Int J Cardiol"},{"key":"2024092410071555000_ytae473-B10","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1161\/01.CIR.90.4.1855","article-title":"Long-term outcome for 120 Japanese patients with Takayasu's disease. Clinical and statistical analyses of related prognostic factors","volume":"90","author":"Ishikawa","year":"1994","journal-title":"Circulation"},{"key":"2024092410071555000_ytae473-B11","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1161\/01.CIR.0000089089.42153.5E","article-title":"Long-term survival after surgical treatment of patients with Takayasu's arteritis","volume":"108","author":"Miyata","year":"2003","journal-title":"Circulation"},{"key":"2024092410071555000_ytae473-B12","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s002709900248","article-title":"Early and long-term results of subclavian angioplasty in aortoarteritis (Takayasu disease): comparison with atherosclerosis","volume":"21","author":"Tyagi","year":"1998","journal-title":"Cardiovasc Interv Radiol"},{"key":"2024092410071555000_ytae473-B13","doi-asserted-by":"crossref","first-page":"427","DOI":"10.3899\/jrheum.150447","article-title":"Retrospective comparison of open versus endovascular procedures for Takayasu arteritis","volume":"43","author":"Labarca","year":"2016","journal-title":"J Rheumatol"},{"key":"2024092410071555000_ytae473-B14","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.jacc.2022.10.024","article-title":"Outcomes of percutaneous intervention in patients with Takayasu arteritis","volume":"81","author":"Joseph","year":"2023","journal-title":"Jacc"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/advance-article-pdf\/doi\/10.1093\/ehjcr\/ytae473\/59015277\/ytae473.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/8\/9\/ytae473\/59277592\/ytae473.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/8\/9\/ytae473\/59277592\/ytae473.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T12:44:01Z","timestamp":1727181841000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytae473\/7748922"}},"subtitle":[],"editor":[{"given":"Christian","family":"Sohns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Megha","family":"Agarwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,9,1]]},"references-count":14,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytae473","relation":{},"ISSN":["2514-2119"],"issn-type":[{"value":"2514-2119","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,9]]},"published":{"date-parts":[[2024,9,1]]},"article-number":"ytae473"}}