{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:51:25Z","timestamp":1753876285825,"version":"3.41.2"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T00:00:00Z","timestamp":1728000000000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Membranous interventricular septum aneurysm (MISA) is a rare abnormality occurring in 0.3% of patients with congenital heart disease, which thereby increases anatomical complexity.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>Transcatheter aortic valve replacement (TAVR) procedure was planned for a 71-year-old female patient from East Asia with a type 1 bicuspid aortic valve diagnosed with severe aortic stenosis by transthoracic echocardiography (TTE). Pre-procedural multidetector computed tomography (MDCT) clearly revealed an extremely horizontal aorta and a MISA originating from the sub-annulus with the upper edge extending 7.2\u2005mm above the annulus. A probable communicating flow between the left ventricle and the aorta was confirmed by reviewing the TTE images. Moreover, there was a calcified raphe between the left- and right-coronary cusps. A downsized balloon-expandable valve (a 23\u2005mm Sapien 3 valve with an additional 2\u2005mL dilation) was therefore chosen and deployed with a 100\/0 aortic\/ventricular ratio position. The TTE post-implantation indicated a trace perivalvular leakage. The cardiac MDCT performed post-procedure, at the 6-month, and 12-month follow-ups demonstrated complete sealing and significant healing of the aneurysm.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Transcatheter aortic valve replacement utilizing a balloon-expandable valve was successfully performed for a case with membranous interventricular septum aneurysm extending above the annulus. Comprehensive imaging analysis before the procedure is crucial for TAVR with challenging anatomical conditions.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytae523","type":"journal-article","created":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T16:49:32Z","timestamp":1728060572000},"source":"Crossref","is-referenced-by-count":0,"title":["Transcatheter aortic valve replacement in a bicuspid aortic valve with membranous interventricular septum aneurysm communicating with aortic root: a case report"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3353-9139","authenticated-orcid":false,"given":"Ziwei","family":"Xi","sequence":"first","affiliation":[{"name":"Interventional Center of Valvular Heart Disease, Beijing Anzhen Hospital, Capital Medical University , No. 2 Anzhen Road, Chaoyang District, Beijing 100029 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Yao","sequence":"additional","affiliation":[{"name":"Interventional Center of Valvular Heart Disease, Beijing Anzhen Hospital, Capital Medical University , No. 2 Anzhen Road, Chaoyang District, Beijing 100029 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5758-2539","authenticated-orcid":false,"given":"Guangyuan","family":"Song","sequence":"additional","affiliation":[{"name":"Interventional Center of Valvular Heart Disease, Beijing Anzhen Hospital, Capital Medical University , No. 2 Anzhen Road, Chaoyang District, Beijing 100029 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,10,4]]},"reference":[{"key":"2024103011473062300_ytae523-B1","first-page":"123","article-title":"Aneurysm of the membranous ventricular septum causing obstruction of the right ventricular outflow tract in a case of ventricular septal defect","volume":"283","author":"Perasalo","year":"1961","journal-title":"Acta Chir Scand Suppl"},{"key":"2024103011473062300_ytae523-B2","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/eurheartj\/ehab395","article-title":"2021 ESC\/EACTS guidelines for the management of valvular heart disease","volume":"43","author":"Vahanian","year":"2022","journal-title":"Eur Heart J"},{"key":"2024103011473062300_ytae523-B3","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1161\/CIRCULATIONAHA.113.002947","article-title":"Anatomical and procedural features associated with aortic root rupture during balloon-expandable transcatheter aortic valve replacement","volume":"128","author":"Barbanti","year":"2013","journal-title":"Circulation"},{"key":"2024103011473062300_ytae523-B4","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1016\/j.jcin.2021.03.027","article-title":"The impact of aortic angulation on contemporary transcatheter aortic valve replacement outcomes","volume":"14","author":"Medranda","year":"2021","journal-title":"JACC Cardiovasc Interv"},{"key":"2024103011473062300_ytae523-B5","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s13244-015-0456-3","article-title":"Interventricular membranous septal aneurysm: CT and MR manifestations","volume":"7","author":"Carcano","year":"2016","journal-title":"Insights Imaging"},{"key":"2024103011473062300_ytae523-B6","doi-asserted-by":"crossref","first-page":"e009407","DOI":"10.1161\/CIRCINTERVENTIONS.120.009407","article-title":"Systematic approach to high implantation of SAPIEN-3 valve achieves a lower rate of conduction abnormalities including pacemaker implantation","volume":"14","author":"Sammour","year":"2021","journal-title":"Circ Cardiovasc Interv"},{"key":"2024103011473062300_ytae523-B7","doi-asserted-by":"crossref","first-page":"101762","DOI":"10.1016\/j.jaccas.2023.101762","article-title":"Pure aortic regurgitation complicated by membranous interventricular septum aneurysm treated with transcatheter aortic valve replacement","volume":"10","author":"Kassis","year":"2023","journal-title":"JACC Case Rep"}],"container-title":["European Heart Journal - 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