{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:50:49Z","timestamp":1753876249331,"version":"3.41.2"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T00:00:00Z","timestamp":1742947200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Intracardiac thrombus-in-transit is a potentially fatal condition, seldom detected in real time.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>We present a case of a 30-year-old pregnant woman with thalassemia intermedia and asplenia, who experienced a combined respiratory-haemodynamic collapse following an emergent caesarean section performed for eclampsia, and in whom a large mass transversing a patent foramen ovale was observed on bedside echocardiography. In view of the patient\u2019s unstable condition, mass\u2019 size and location as well as accompanying inter-atrial communication\u2014all of which contributed to an imminent threat to cerebral circulation\u2014and temporal proximity to abdominal surgery and epidural anaesthesia, an immediate open-heart surgery was decided upon that included mass excision and patent foramen ovale closure, and after which the patient quickly and fully recovered. Histopathologic examination of the mass revealed a mixture of thrombotic and amniotic fluid elements. Acute pulmonary embolism was eventually confirmed by computed tomography performed on post-operative day 2.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Early echocardiography and surgical intervention, as dictated by a multidisciplinary collaboration, allowed for a favourable outcome in our patient, emphasizing their pivotal role in the management of a life-threatening presentation of an intracardiac thrombus-in-transit.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaf145","type":"journal-article","created":{"date-parts":[[2025,3,29]],"date-time":"2025-03-29T16:55:14Z","timestamp":1743267314000},"source":"Crossref","is-referenced-by-count":0,"title":["Giant intracardiac thrombus-in-transit in a woman with sudden respiratory-haemodynamic compromise following cesarean section for eclampsia: a case report"],"prefix":"10.1093","volume":"9","author":[{"given":"Olga","family":"Morelli","sequence":"first","affiliation":[{"name":"Department of Cardiology, Rabin Medical Center , 39 Jabotinsky St, Petach Tikva 4941492 ,","place":["Israel"]},{"name":"Faculty of Medicine, Tel Aviv University , 35 Klachkin St, Tel Aviv 6997801 ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan M","family":"Gorfil","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Tel Aviv University , 35 Klachkin St, Tel Aviv 6997801 ,","place":["Israel"]},{"name":"Department of Cardio-Thoracic Surgery, Rabin Medical Center , 39 Jabotinsky St, Petach Tikva 4941492 ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaron D","family":"Barac","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Tel Aviv University , 35 Klachkin St, Tel Aviv 6997801 ,","place":["Israel"]},{"name":"Department of Cardio-Thoracic Surgery, Rabin Medical Center , 39 Jabotinsky St, Petach Tikva 4941492 ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3429-2219","authenticated-orcid":false,"given":"Yaron","family":"Shapira","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rabin Medical Center , 39 Jabotinsky St, Petach Tikva 4941492 ,","place":["Israel"]},{"name":"Faculty of Medicine, Tel Aviv University , 35 Klachkin St, Tel Aviv 6997801 ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9670-4026","authenticated-orcid":false,"given":"Alon","family":"Shechter","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rabin Medical Center , 39 Jabotinsky St, Petach Tikva 4941492 ,","place":["Israel"]},{"name":"Faculty of Medicine, Tel Aviv University , 35 Klachkin St, Tel Aviv 6997801 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different modalities for treatment of right heart thrombi in transit: a pooled analysis","volume":"20","author":"Athappan","year":"2015","journal-title":"Vasc Med"},{"key":"2025041511114081500_ytaf145-B4","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1378\/chest.09-0961","article-title":"Impending paradoxical embolism: systematic review of prognostic factors and treatment","volume":"137","author":"Myers","year":"2010","journal-title":"Chest"},{"key":"2025041511114081500_ytaf145-B5","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.amjmed.2016.11.041","article-title":"Free-floating right heart thrombi","volume":"130","author":"Dalen","year":"2017","journal-title":"Am J Med"},{"key":"2025041511114081500_ytaf145-B6","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1093\/eurheartj\/ehz405","article-title":"2019 ESC guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European respiratory society 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