{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:51:29Z","timestamp":1753876289265,"version":"3.41.2"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T00:00:00Z","timestamp":1745539200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,2]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Pulmonary artery angiosarcoma is a rare and highly malignant tumour. Its clinical presentation often mimics common pulmonary disorders such as pulmonary embolism or pneumonia, which frequently leads to misdiagnosis. Due to its aggressive nature and typical diagnostic delay, prognosis is generally poor, with survival often limited to a few months post-diagnosis.<\/jats:p>\n <\/jats:sec>\n \n Case Summary<\/jats:title>\n A 70-year-old female with a history of hypertension and no previous cardiac issues presented with progressive exertional dyspnoea unresponsive to anticoagulation after a diagnosis of pulmonary embolism. A chest computed tomography (CT) initially suggested a pulmonary embolism with an endoluminal filling defect in the right pulmonary artery. However, further investigation revealed a mass in the right pulmonary artery with a subsequent obliteration of the perihilar fat spaces, leading to a diagnosis of pulmonary artery angiosarcoma.<\/jats:p>\n <\/jats:sec>\n \n Discussion<\/jats:title>\n This case underscores the importance of considering pulmonary artery angiosarcoma in differential diagnoses for persistent pulmonary symptoms, especially when imaging and clinical signs are atypical for thromboembolic disease. Early recognition and a multidisciplinary approach are essential for improving outcomes in this rare but lethal malignancy, where prompt diagnosis may extend survival significantly.<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaf207","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T07:03:38Z","timestamp":1745564618000},"source":"Crossref","is-referenced-by-count":0,"title":["Pulmonary embolism with pulmonary hypertension or something far worse? Unveiling a rare and lethal pulmonary artery angiosarcoma: a case report"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0925-1618","authenticated-orcid":false,"given":"Gianluca","family":"Guarnieri","sequence":"first","affiliation":[{"name":"Department of Biomedical and Clinical Sciences, University of Milan , via Festa del Perdono, Milan 20122 ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Briguglia","sequence":"additional","affiliation":[{"name":"Division of University Cardiology, IRCCS Ospedale Galeazzi Sant\u2019Ambrogio , via Belgioioso, Milan 20157 ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edoardo","family":"Conte","sequence":"additional","affiliation":[{"name":"Division of University Cardiology, IRCCS Ospedale Galeazzi Sant\u2019Ambrogio , via Belgioioso, Milan 20157 ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Andreini","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Clinical Sciences, University of Milan , via Festa del Perdono, Milan 20122 ,","place":["Italy"]},{"name":"Division of University Cardiology, IRCCS Ospedale Galeazzi Sant\u2019Ambrogio , via Belgioioso, Milan 20157 ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,4,25]]},"reference":[{"key":"2025050622070173800_ytaf207-B1","doi-asserted-by":"crossref","first-page":"ivac096","DOI":"10.1093\/icvts\/ivac096","article-title":"Angiosarcoma of the main pulmonary artery-hand-made conduit reconstruction","volume":"35","author":"Darawsha","year":"2022","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"2025050622070173800_ytaf207-B2","first-page":"e17059","article-title":"Clinical detection of primary pulmonary angiosarcoma","volume":"13","author":"Khalid","year":"2021","journal-title":"Cureus"},{"key":"2025050622070173800_ytaf207-B3","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1177\/0218492312441780","article-title":"Six-year survival of a patient with pulmonary artery angiosarcoma","volume":"20","author":"Chaubey","year":"2012","journal-title":"Asian Cardiovasc Thorac Ann"},{"key":"2025050622070173800_ytaf207-B4","doi-asserted-by":"crossref","first-page":"2045894018785047","DOI":"10.1177\/2045894018785047","article-title":"Don\u2019t stop at first glance: pulmonary artery angiosarcoma mimicking chronic thromboembolic pulmonary hypertension","volume":"8","author":"Correale","year":"2018","journal-title":"Pulm Circ"},{"key":"2025050622070173800_ytaf207-B5","doi-asserted-by":"crossref","first-page":"E509","DOI":"10.1503\/cmaj.151417","article-title":"Primary pulmonary artery angiosarcoma mimicking pulmonary embolism in a 66-year-old man with dyspnea","volume":"188","author":"Desmarais","year":"2016","journal-title":"C Can Med Assoc J = J l\u2019Association medicale Can"},{"key":"2025050622070173800_ytaf207-B6","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1055\/a-2173-7729","article-title":"Recurrent venous thromboembolism in patients on anticoagulation: an update based on the revised AWMF S2k guideline","volume":"44","author":"Klamroth","year":"2024","journal-title":"Hamostaseologie"},{"key":"2025050622070173800_ytaf207-B7","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.jaccao.2024.07.016","article-title":"Anthracycline cardiotoxicity in adult cancer patients: JACC: CardioOncology state-of-the-art review","volume":"6","author":"Camilli","year":"2024","journal-title":"JACC CardioOncol"}],"container-title":["European Heart Journal - 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