{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:50:47Z","timestamp":1753876247155,"version":"3.41.2"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T00:00:00Z","timestamp":1749081600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Primary cardiac lymphoma (PCL) involves the heart almost exclusively although it can extend to surrounding structures including the pericardium. Most PCLs in adults are of B-cell origin and their signs and symptoms are generally non-specific and depend on their location and size. In general, cancer patients usually have a slim chance of receiving heart transplantation (OHT), although it\u2019s not an absolute contraindication depending on the decision of the multidisciplinary team and the experience of each institution.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case Summary<\/jats:title>\n                  <jats:p>A 48-year-old man, with an ultimate diagnosis of primary cardiac follicular B-cell lymphoma presented to our hospital mimicking hypertrophic cardiomyopathy. He initially presented with worsening heart failure and ventricular tachycardia storm (VT-S) that required urgent cardiac OHT. The final pathological analysis of the explanted heart revealed the presence of a PCL without extra-cardiac extension. In addition to initial immunosuppression with mycophenolate mophethyl, corticosteroids, and tacrolimus, he was switched to Everolimus and dose reduction of Tacrolimus. Rituximab + Bendamustine was initiated to reduce the risk of cardiotoxicity and myelotoxicity associated to R-CHOP. The follow-up body PET-CT, trans-thoracic echocardiogram, cardiac magnetic resonance imagings and biopsies were normal. During a regular follow-up heart biopsy procedure to ascertain rejection, the patient developed torrential tricuspid regurgitation and required surgical valve replacement.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>After 5.5 years of follow-up, the patient remains asymptomatic, with normal graft function, in NYHA FC I, and without oncological relapses despite receiving a modified chemotherapy regimen. Selected patients with a PCL can be managed with OHT and a modified chemotherapy regimen. They could also be followed up using a non-invasive approach to monitor rejection.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaf279","type":"journal-article","created":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T08:20:48Z","timestamp":1749111648000},"source":"Crossref","is-referenced-by-count":0,"title":["Cardiac lymphoma requiring urgent heart transplant due to ventricular tachycardia storm: a case report"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5867-2876","authenticated-orcid":false,"given":"Juli\u00e1n","family":"Lugo-Pe\u00f1a","sequence":"first","affiliation":[{"name":"Department of Clinical Cardiology, Fundaci\u00f3n Cardioinfantil-Instituto de Cardiolog\u00eda , Calle 163A # 13B-60, Bogot\u00e1 110311 ,","place":["Colombia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9ctor M","family":"Medina","sequence":"additional","affiliation":[{"name":"Cardiac Imaging, Texas Heart Institute, 6770 Bertner Avenue , Houston, TX 77030, USA"},{"name":"Baylor College of Medicine, 1 Baylor Plz, Houston, TX 77030 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan P","family":"Uma\u00f1a","sequence":"additional","affiliation":[{"name":"Chair, Division of Thoracic & Cardiovascular Surgery, Cleveland Clinic , 3100 Weston Road, Weston, FL 33331, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Daniela","family":"Valderrama-Achury","sequence":"additional","affiliation":[{"name":"Research Institute of the McGill University Health Centre , 845 Sherbrooke Stw, Montreal, Quebec , , H3A 0G4","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Torres","sequence":"additional","affiliation":[{"name":"Heart Failure Unit Los Cobos Medical Center , Avenida 9 \" 131-40, Bogot\u00e1 111321 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