{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T10:32:39Z","timestamp":1785148359174,"version":"3.55.0"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2025,6,14]],"date-time":"2025-06-14T00:00:00Z","timestamp":1749859200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Recurrent pericardial syndromes secondary to Boerhaave\u2019s syndrome (spontaneous oesophageal rupture) are exceedingly rare and represent diagnostic and therapeutic challenges.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>We present a case of a 46-year-old male with recurrent pericardial effusions and cardiac tamponade following Boerhaave\u2019s syndrome. Initial management included surgical repair of the oesophageal rupture and medical treatment for the subsequent effusions with colchicine, non-steroidal anti-inflammatory drugs, and corticosteroids. The patient experienced multiple recurrences despite medical therapy, necessitating a multidisciplinary approach. Ultimately, a pericardiectomy was performed, revealing significant pericardial adhesions and inflammation. Post-operative recovery was uneventful with recurrence of effusion.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>This case underscores the importance of early recognition and multidisciplinary management in recurrent pericardial syndromes associated with oesophageal rupture. While first-line medical therapy can be effective, persistent or refractory cases may require surgical intervention. Early surgical consultation should be considered when medical management fails.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaf283","type":"journal-article","created":{"date-parts":[[2025,6,14]],"date-time":"2025-06-14T11:43:02Z","timestamp":1749901382000},"source":"Crossref","is-referenced-by-count":1,"title":["Recurrent pericardial syndromes following Boerhaave\u2019s syndrome: a complex clinical presentation and case report"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7795-0114","authenticated-orcid":false,"given":"Musab","family":"Eltayeb","sequence":"first","affiliation":[{"name":"Cardiology Department, Mercy University Hospital , Granville PI, Cork T12WE28 ,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke","family":"Byrne","sequence":"additional","affiliation":[{"name":"Cardiology Department, Mercy University Hospital , Granville PI, Cork T12WE28 ,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gearoid","family":"Fitzgerald","sequence":"additional","affiliation":[{"name":"Cardiology Department, Mercy University Hospital , Granville PI, Cork T12WE28 ,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl","family":"Vaughan","sequence":"additional","affiliation":[{"name":"Cardiology Department, Mercy University Hospital , Granville PI, Cork T12WE28 ,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,6,14]]},"reference":[{"key":"2025070712265866800_ytaf283-B1","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1055\/s-0030-1250347","article-title":"Oesophageal perforations in Iceland: a whole population study on incidence, aetiology, and surgical outcome","volume":"58","author":"Vidarsdottir","year":"2010","journal-title":"Thorac Cardiovasc Surg"},{"key":"2025070712265866800_ytaf283-B2","first-page":"1","article-title":"Epidemiology, diagnosis, and management of esophageal perforations: a systematic review","volume":"30","author":"Sdralis","year":"2017","journal-title":"This oesophagus"},{"key":"2025070712265866800_ytaf283-B3","article-title":"Oesophageal perforation and tears","volume-title":"StatPearls [Internet]","author":"Kassem","year":"2023"},{"key":"2025070712265866800_ytaf283-B4","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.ehj.2004.02.002","article-title":"Guidelines on the diagnosis and management of pericardial diseases: executive summary","volume":"25","author":"Maisch","year":"2004","journal-title":"Eur Heart J"},{"key":"2025070712265866800_ytaf283-B5","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1093\/eurheartj\/ehv318","article-title":"2015 ESC Guidelines for the diagnosis and management of pericardial diseases: The Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology (ESC)Endorsed by: The European Association for Cardio-Thoracic Surgery (EACTS)","volume":"36","author":"Adler","year":"2015","journal-title":"Eur Heart J"},{"key":"2025070712265866800_ytaf283-B6","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1097\/HCO.0b013e3283524fbe","article-title":"Contemporary management of pericardial diseases","volume":"27","author":"Imazio","year":"2012","journal-title":"Curr Opin Cardiol"},{"key":"2025070712265866800_ytaf283-B7","doi-asserted-by":"crossref","first-page":"2012-6","DOI":"10.1161\/CIRCULATIONAHA.105.542738","article-title":"Colchicine in addition to conventional therapy for acute pericarditis: results of the COPE trial","volume":"112","author":"Imazio","year":"2005","journal-title":"Circulation"},{"key":"2025070712265866800_ytaf283-B8","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/S0002-9149(99)80558-X","article-title":"Incidence of specific etiology and role of methods for specific etiologic diagnosis of primary acute pericarditis","volume":"75","author":"Torres","year":"1995","journal-title":"Am J Cardiol"},{"key":"2025070712265866800_ytaf283-B9","doi-asserted-by":"crossref","first-page":"572","DOI":"10.4065\/mcp.2010.0046","article-title":"Pericardial disease: diagnosis and management","volume":"85","author":"Khandaker","year":"2010","journal-title":"Mayo Clin Proc"},{"key":"2025070712265866800_ytaf283-B10","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1136\/heartjnl-2018-313532","article-title":"Outcomes of idiopathic chronic large pericardial effusion","volume":"105","author":"Zayas","year":"2019","journal-title":"Heart"},{"key":"2025070712265866800_ytaf283-B11","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/j.jacc.2003.09.055","article-title":"Day-hospital treatment of acute pericarditis: a management program for outpatient therapy","volume":"43","author":"Imazio","year":"2004","journal-title":"J Am Coll Cardiol"}],"container-title":["European Heart Journal - 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