{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:13:55Z","timestamp":1758845635244,"version":"3.44.0"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T00:00:00Z","timestamp":1756771200000},"content-version":"vor","delay-in-days":4,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>It was in 1866 when Wilhelm Ebstein first described a rare case of a 19-year-old cyanotic patient with tricuspid valve regurgitation caused by a congenital malformation. Since then, Ebstein\u2019s anomaly (EA) has been recognized as a condition that exhibits a diverse clinical course with a formidable challenge for clinicians in terms of diagnosis, management, and prognosis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>We present a case series of four patients with EA, shedding light on the varied clinical manifestations, treatment approaches, and outcomes that underscore the multifaceted nature of this condition.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>The management of EA requires a comprehensive and individualized approach in specialized centres. The cardiologists responsible for the long-term care of these patients are faced with various challenging \u2018dilemmas\u2019 in the clinical course of the disease at different stages. The evolving landscape of cardiology offers a promising avenue for improving the outcomes and quality of life of patients with EA.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaf424","type":"journal-article","created":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T18:52:53Z","timestamp":1756839173000},"source":"Crossref","is-referenced-by-count":0,"title":["A multifaceted clinical portrait of Ebstein\u2019s anomaly: a case series"],"prefix":"10.1093","volume":"9","author":[{"given":"Panayotis K","family":"Vlachakis","sequence":"first","affiliation":[{"name":"Adult Congenital Heart Centre and Centre for Pulmonary Hypertension, First Cardiology Department, Hippokration General Hospital, Athens Medical School, National and Kapodistrian University of Athens , 114 Vasilissis Sophias, Athens 11527 ,","place":["Greece"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Nyktari","sequence":"additional","affiliation":[{"name":"CMR Unit, Onassis Cardiac Surgery Center , 356 Andrea Syggrou Avenue, Kallithea 17674 ,","place":["Greece"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Oikonomou","sequence":"additional","affiliation":[{"name":"Adult Congenital Heart Centre and Centre for Pulmonary Hypertension, First Cardiology Department, Hippokration General Hospital, Athens Medical School, National and Kapodistrian University of Athens , 114 Vasilissis Sophias, Athens 11527 ,","place":["Greece"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2616-7952","authenticated-orcid":false,"given":"Anastasios","family":"Apostolos","sequence":"additional","affiliation":[{"name":"Adult Congenital Heart Centre and Centre for Pulmonary Hypertension, First Cardiology Department, Hippokration General Hospital, Athens Medical School, National and Kapodistrian University of Athens , 114 Vasilissis Sophias, Athens 11527 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