{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T04:44:20Z","timestamp":1758343460220,"version":"3.44.0"},"reference-count":3,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T00:00:00Z","timestamp":1757116800000},"content-version":"vor","delay-in-days":8,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Frequent premature ventricular contractions (PVCs) and valvular dysfunction are established contributors to worsening heart failure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>We present a 67-year-old male with dilated cardiomyopathy, severe aortic regurgitation, and unifocal left ventricle-originated PVCs (37.8% burden) refractory to guideline-directed medical therapy and cardiac devices. Due to high surgical risk, a combined transapical transcatheter aortic valve implantation and PVC ablation was performed. Postoperatively, PVCs were eliminated, left ventricular ejection fraction improved from 35% to 55%, and cardiac dimensions normalized significantly.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>This case highlights the feasibility of a single apical approach for addressing both valvular and arrhythmic pathologies in high-risk patients, offering a novel strategy to mitigate heart failure progression.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaf441","type":"journal-article","created":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T08:38:12Z","timestamp":1757147892000},"source":"Crossref","is-referenced-by-count":0,"title":["Combined transapical transcatheter aortic valve implantation and premature ventricular contraction ablation in a high-risk cardiomyopathy patient: a case report"],"prefix":"10.1093","volume":"9","author":[{"given":"Yu-Bin","family":"Li","sequence":"first","affiliation":[{"name":"Department of Cardiology, The First Affiliated Hospital, Sun Yat-Sen University , No. 58 Zhongshan Road 2, 510000 Guangzhou ,","place":["China"]},{"name":"NHC Key Laboratory of Assisted Circulation , No. 58 Zhongshan Road 2, 510000 Guangzhou ,","place":["China"]},{"name":"Department of Cardiology, People\u2019s Hospital of Deqing County , No. 2 Rencuixiang Road, 526000 Zhaoqing ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3562-7976","authenticated-orcid":false,"given":"Yang","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The First Affiliated Hospital, Sun Yat-Sen University , No. 58 Zhongshan Road 2, 510000 Guangzhou ,","place":["China"]},{"name":"NHC Key Laboratory of Assisted Circulation , No. 58 Zhongshan Road 2, 510000 Guangzhou ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The First Affiliated Hospital, Sun Yat-Sen University , No. 58 Zhongshan Road 2, 510000 Guangzhou ,","place":["China"]},{"name":"NHC Key Laboratory of Assisted Circulation , No. 58 Zhongshan Road 2, 510000 Guangzhou ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhong-Kai","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, First Affiliated Hospital of Sun Yat-sen University , No. 58 Zhongshan Road 2, 510000 Guangzhou ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Chun","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The First Affiliated Hospital, Sun Yat-Sen University , No. 58 Zhongshan Road 2, 510000 Guangzhou ,","place":["China"]},{"name":"NHC Key Laboratory of Assisted Circulation , No. 58 Zhongshan Road 2, 510000 Guangzhou ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,9,6]]},"reference":[{"key":"2025091918424288900_ytaf441-B1","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1016\/j.jacc.2021.12.011","article-title":"2022 AHA\/ACC\/HFSA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"79","author":"Heidenreich","year":"2022","journal-title":"J Am Coll Cardiol"},{"key":"2025091918424288900_ytaf441-B2","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1016\/j.jacc.2024.03.416","article-title":"Arrhythmia-induced cardiomyopathy: JACC state-of-the-art review","volume":"83","author":"Shoureshi","year":"2024","journal-title":"J Am Coll Cardiol"},{"key":"2025091918424288900_ytaf441-B3","doi-asserted-by":"crossref","first-page":"e036462","DOI":"10.1161\/JAHA.124.036462","article-title":"Burden and temporal trends of valvular heart disease-related heart failure from 1990 to 2019 and projection up to 2030 in group of 20 countries: an analysis for the Global Burden of Disease Study 2019","volume":"13","author":"Zhang","year":"2024","journal-title":"J Am Heart Assoc"}],"container-title":["European Heart Journal - 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