{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T16:38:04Z","timestamp":1793637484478,"version":"4.5.1"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:00:00Z","timestamp":1758844800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cardiomyopathy is an infrequently reported complication of Addison\u2019s disease, which is unique in its reversibility. We report a rare case where cardiomyopathy was the initial manifestation of Addison's disease. This case report explores the pathophysiological association between Addison's disease and heart failure, emphasizing the importance of recognizing this potential link in patients presenting with heart failure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>A 39-year-old gentleman presents with classical features of heart failure, which was confirmed by his transthoracic echocardiogram. Addison\u2019s disease was suspected due to hyponatremia, hyperkalaemia, and low cortisol levels. A short synacthen test confirmed the diagnosis, and he was started on dual therapy with hydrocortisone and fludrocortisone. His left ventricular function returned to normal within 5 days of dual therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case report underscores the critical association between Addison's disease and heart failure, highlighting the importance of considering adrenal insufficiency as a potential underlying factor in cardiac dysfunction. It serves as a reminder of the complex physiological interactions that can cause cardiomyopathy, and further research is vital to improve understanding. Timely recognition and prompt treatment with steroids can lead to rapid reversal of cardiac function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaf455","type":"journal-article","created":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T12:04:49Z","timestamp":1758801889000},"source":"Crossref","is-referenced-by-count":2,"title":["A rare presentation of cardiomyopathy associated with Addison's disease: a case report"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0808-5892","authenticated-orcid":false,"given":"Siphy","family":"Joseph","sequence":"first","affiliation":[{"name":"Department of Cardiology, Dorset County Hospital , Williams Avenue, Dorchester DT1 2JY ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6251-1103","authenticated-orcid":false,"given":"Fraser N","family":"Witherow","sequence":"additional","affiliation":[{"name":"Cardiologist, Dorset County Hospital, Williams Avenue, Dorchester DT1 2JY ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0907-3068","authenticated-orcid":false,"given":"Midhun","family":"Paul","sequence":"additional","affiliation":[{"name":"Stroke, Dorset County Hospital, Williams Avenue, Dorchester DT1 2JY ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1494-100X","authenticated-orcid":false,"given":"Chris","family":"Steadman","sequence":"additional","affiliation":[{"name":"Cardiologist, University Hospital Dorset, Castle Lane East, Bournemouth BH7 7HA ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,9,26]]},"reference":[{"key":"2025110903450674700_ytaf455-B1","first-page":"Article 4362514","article-title":"Addison\u2019s disease and dilated cardiomyopathy: a case report and review of the literature","volume":"2016","author":"Mozolevska","year":"2016","journal-title":"Case Rep Cardiol"},{"key":"2025110903450674700_ytaf455-B2","first-page":"377","article-title":"Reversible cardiomyopathy associated with Addison's disease","volume":"16","author":"Afzal","year":"2000","journal-title":"Can J Cardiol"},{"key":"2025110903450674700_ytaf455-B3","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/0002-9343(83)91074-4","article-title":"Cardiac failure in Addison's disease","volume":"74","author":"Knowlton","year":"1983","journal-title":"Am J Med"},{"key":"2025110903450674700_ytaf455-B4","first-page":"1","article-title":"Reversible stress-induced cardiomyopathy in adrenal insufficiency","volume":"1","author":"Salman","year":"2018","journal-title":"Clin Cardiol Cardiovasc"},{"key":"2025110903450674700_ytaf455-B5","first-page":"1172","article-title":"An interesting case of adrenal insufficiency with cardiomyopathy during index adrenal crisis presentation followed by recurrent pericarditis","volume":"9","author":"Avula","year":"2021","journal-title":"J Cardiol Clin Res"},{"key":"2025110903450674700_ytaf455-B6","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1186\/s13256-018-1899-1","article-title":"Reversible dilated cardiomyopathy as a complication of adrenal cortex insufficiency: a case report","volume":"12","author":"Alkhateeb","year":"2018","journal-title":"J Med Case Rep"},{"key":"2025110903450674700_ytaf455-B7","first-page":"e321","article-title":"Reversible heart failure as a result of newly diagnosed primary adrenal insufficiency","volume":"2","author":"Hyland","year":"2016","journal-title":"AACE Clin Case Rep"},{"key":"2025110903450674700_ytaf455-B8","first-page":"411","article-title":"Reversible biventricular heart failure due to primary adrenal insufficiency, JACC","volume":"2","author":"Devareddy","year":"2020","journal-title":"Case Rep"}],"container-title":["European Heart Journal - 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