{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T14:28:32Z","timestamp":1763476112006,"version":"3.45.0"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Science and Technology Innovation 2030 Major Project","award":["2024ZD0521900"],"award-info":[{"award-number":["2024ZD0521900"]}]},{"name":"Clinical and Translational Medicine Research Program","award":["2023-LC05"],"award-info":[{"award-number":["2023-LC05"]}]},{"DOI":"10.13039\/501100005150","name":"Chinese Academy of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005150","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Robotic-assisted procedures are rapidly advancing in interventional cardiology and have shown advantages in performing atrial fibrillation ablation. However, their application in combination with pulsed field ablation (PFA) remains unexplored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>We report the first in vivo experience of robotic-assisted PFA. The robotic-assisted PFA system comprises of a robotic articulating arm with three sterile, single-use functional modules, a workstation console, and a control computer. Following transseptal puncture and electrical mapping, two experienced operators performed pulmonary vein isolation and superior vena cava isolation in a swine model using the robotic system integrated with a guiding sheath and a PFA catheter. The procedure was conducted under fluoroscopy, while operators controlled the system remotely via the console in a zero-radiation environment. Post-procedural voltage mapping and histological analysis confirmed the feasibility of robotic-assisted PFA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The primary advantage of robotic-assisted PFA is the potential to enable remote operation. It may also improve catheter stability and reduce the learning curve for performing PFA. Potential risks of robotic-assisted PFA include violent damage to cardiac tissue and complications associated with PFA. The robotic-assisted PFA system is sensitive and accurate when operated on a swine model, though several challenges exist in translating findings from a swine model to human clinical practice, and further studies are needed to evaluate its safety and efficacy before clinical implementation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaf518","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T13:01:11Z","timestamp":1763038871000},"source":"Crossref","is-referenced-by-count":0,"title":["First\n                    <i>in vivo<\/i>\n                    robotic-assisted pulsed field ablation for atrial fibrillation in a swine model: a case report"],"prefix":"10.1093","volume":"9","author":[{"given":"Nianqin","family":"Zhang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , No. 167 Beilishi Rd, Xicheng District, Beijing 100037 ,","place":["People\u2019s Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi","family":"Cai","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , No. 167 Beilishi Rd, Xicheng District, Beijing 100037 ,","place":["People\u2019s Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4003-4323","authenticated-orcid":false,"given":"Yan","family":"Yao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , No. 167 Beilishi Rd, Xicheng District, Beijing 100037 ,","place":["People\u2019s Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5610-5974","authenticated-orcid":false,"given":"Ligang","family":"Ding","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , No. 167 Beilishi Rd, Xicheng District, Beijing 100037 ,","place":["People\u2019s Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Hua","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , No. 167 Beilishi Rd, Xicheng District, Beijing 100037 ,","place":["People\u2019s Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,11,18]]},"reference":[{"key":"2025111809234003800_ytaf518-B1","doi-asserted-by":"crossref","first-page":"e007517","DOI":"10.1161\/CIRCEP.119.007517","article-title":"Remote magnetic versus manual catheter navigation for atrial fibrillation ablation: a meta-analysis","volume":"12","author":"Virk","year":"2019","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2025111809234003800_ytaf518-B2","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1016\/j.hrthm.2011.07.032","article-title":"Robotic catheter ablation of left ventricular tachycardia: initial experience","volume":"8","author":"Valderr\u00e1bano","year":"2011","journal-title":"Heart Rhythm"},{"key":"2025111809234003800_ytaf518-B3","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1056\/NEJMoa2307291","article-title":"Pulsed field or conventional thermal ablation for paroxysmal atrial fibrillation","volume":"389","author":"Reddy","year":"2023","journal-title":"N Engl J Med"},{"key":"2025111809234003800_ytaf518-B4","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1016\/j.jcin.2024.08.026","article-title":"First-in-man experience of telerobotic transcatheter edge-to-edge repair with pure echo guidance","volume":"17","author":"Wang","year":"2024","journal-title":"JACC Cardiovasc Interv"},{"key":"2025111809234003800_ytaf518-B5","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1093\/europace\/euu364","article-title":"A randomized prospective mechanistic cardiac magnetic resonance study correlating catheter stability, late gadolinium enhancement and 3 year clinical outcomes in robotically assisted vs. standard catheter ablation","volume":"17","author":"Arujuna","year":"2015","journal-title":"Europace"},{"key":"2025111809234003800_ytaf518-B6","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1016\/j.jacep.2025.04.017","article-title":"NEMESIS-PFA: investigating collateral tissue injury associated with pulsed field ablation","volume":"11","author":"Lakkireddy","year":"2025","journal-title":"JACC Clin Electrophysiol"},{"key":"2025111809234003800_ytaf518-B7","doi-asserted-by":"crossref","first-page":"euae016","DOI":"10.1093\/europace\/euae016","article-title":"Pulsed electric field, cryoballoon, and radiofrequency for paroxysmal atrial fibrillation ablation: a propensity score-matched comparison","volume":"26","author":"Della Rocca","year":"2023","journal-title":"Europace"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/9\/11\/ytaf518\/65370981\/ytaf518.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/9\/11\/ytaf518\/65370981\/ytaf518.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T14:23:48Z","timestamp":1763475828000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytaf518\/8326610"}},"subtitle":[],"editor":[{"given":"Rachel M A","family":"ter Bekke","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Carlos Minguito","family":"Carazo","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Christian-Hendrik Hendrik","family":"Heeger","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Deepti","family":"Ranganathan","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,10,31]]},"references-count":7,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,10,31]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytaf518","relation":{},"ISSN":["2514-2119"],"issn-type":[{"value":"2514-2119","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,11]]},"published":{"date-parts":[[2025,10,31]]},"article-number":"ytaf518"}}