{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T18:43:32Z","timestamp":1764269012516,"version":"3.46.0"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T00:00:00Z","timestamp":1762560000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>VASCADE MVP\u00ae is a vascular closure device developed to achieve haemostasis of large-bore venous access by deploying a collagen patch in the subcutaneous tissue. While its efficacy and safety have been demonstrated, venous occlusion has not been previously reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>A 72-year-old woman was hospitalized and underwent pulmonary vein isolation for symptomatic paroxysmal atrial fibrillation. Two femoral venous sheaths (10-Fr and 8.5-Fr) were inserted under ultrasound guidance, and haemostasis was achieved using VASCADE MVP Venous Vascular Closure devices. On postoperative day 9, right leg swelling appeared. Contrast-enhanced CT showed stenosis of the right common femoral vein (CFV), and duplex ultrasound revealed a hyperechoic structure distal to the stenosis. Since deep vein thrombosis was suspected, the apixaban dose was adjusted from 10 to 20\u2005mg\/day. Due to persistent symptoms, venography was performed on Day 15, which revealed complete CFV occlusion. Intravascular endoscopy revealed white intraluminal material consistent with residual collagen, and subsequent balloon angioplasty led to partial restoration of blood flow. Given the gradual improvement in symptoms, conservative management was pursued, leading to complete recovery at 2\u2005months as confirmed by duplex ultrasound.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This is the first reported case of venous occlusion likely caused by residual collagen from a collagen-based venous closure device. Balloon angioplasty restored partial blood flow, and surgical intervention was avoided due to the identification of collagen-induced reversible mechanical obstruction. When using VASCADE MVP, operators should be mindful to avoid intravascular deployment of collagen by ensuring proper technique.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaf581","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T13:07:43Z","timestamp":1762434463000},"source":"Crossref","is-referenced-by-count":0,"title":["Femoral vein occlusion after VASCADE MVP resolved without surgery: a case report"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1247-8442","authenticated-orcid":false,"given":"Masaki","family":"Honda","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, Institute of Science Tokyo , Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8510 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8473-7514","authenticated-orcid":false,"given":"Masateru","family":"Takigawa","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Institute of Science Tokyo , Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8510 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taishi","family":"Yonetsu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Institute of Science Tokyo , Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8510 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinsuke","family":"Miyazaki","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Institute of Science Tokyo , Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8510 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3582-6104","authenticated-orcid":false,"given":"Tetsuo","family":"Sasano","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Institute of Science Tokyo , Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8510 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,11,8]]},"reference":[{"key":"2025112713414523700_ytaf581-B1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.jacep.2019.08.013","article-title":"Venous vascular closure system versus manual compression following multiple access electrophysiology procedures: the AMBULATE trial","volume":"6","author":"Natale","year":"2020","journal-title":"JACC Clin Electrophysiol"},{"key":"2025112713414523700_ytaf581-B2","first-page":"288","article-title":"Refractory deep vein thrombosis caused by femoral vein stenosis due to suture-medicated vascular closure device","volume":"32","author":"Ikenouchi","year":"2022","journal-title":"Int J Angiol"},{"key":"2025112713414523700_ytaf581-B3","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.jaccas.2022.03.029","article-title":"Femoral vein occlusion or stenosis using a suture-mediated vascular closure device after catheter ablation","volume":"4","author":"Arai","year":"2022","journal-title":"JACC Case Rep"},{"key":"2025112713414523700_ytaf581-B4","first-page":"639","article-title":"Venous occlusion after incidental edge-to-edge suturing of a venous valve using suture-mediated closure devices","volume":"9","author":"Ogawa","year":"2023","journal-title":"Heart Rhythm Case Rep"},{"key":"2025112713414523700_ytaf581-B5","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1111\/jce.15763","article-title":"Same-day discharge following catheter ablation and venous closure with VASCADE MVP: a postmarket registry","volume":"34","author":"Eldadah","year":"2023","journal-title":"J Cardiovasc Electrophysiol"},{"key":"2025112713414523700_ytaf581-B6","doi-asserted-by":"crossref","first-page":"S161","DOI":"10.1016\/j.hrthm.2024.03.580","article-title":"Adverse events associated with VASCADE MVP venous vascular closure system: a study from Food and Drug Administration MAUDE database","volume":"21","author":"Kewcharoen","year":"2024","journal-title":"Heart Rhythm"},{"volume-title":"VASCADE MVP\u00ae Venous Vascular Closure System (VVCS) 6\u201312F (Venous): Instructions for Use (Model 800-612C; IFU 5686 AC, May 2023)","year":"2023","author":"Cardiva Medical, Inc","key":"2025112713414523700_ytaf581-B7"},{"key":"2025112713414523700_ytaf581-B8","first-page":"1260","article-title":"Efficacy and safety of the VASCADE\u00ae MVP venous vascular closure device in patients undergoing percutaneous left atrial appendage occlusion with WATCHMAN","volume":"104","author":"Golzarian","year":"2024","journal-title":"Catheter Cardiovasc Interv"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/advance-article-pdf\/doi\/10.1093\/ehjcr\/ytaf581\/65244496\/ytaf581.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/9\/12\/ytaf581\/65244496\/ytaf581.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/9\/12\/ytaf581\/65244496\/ytaf581.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T18:41:55Z","timestamp":1764268915000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytaf581\/8317025"}},"subtitle":[],"editor":[{"given":"Patrick","family":"Badertscher","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Boldizsar","family":"Kovacs","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Felix","family":"G\u00f5tzinger","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Deepti","family":"Ranganathan","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,11,8]]},"references-count":8,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,11,27]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytaf581","relation":{},"ISSN":["2514-2119"],"issn-type":[{"type":"electronic","value":"2514-2119"}],"subject":[],"published-other":{"date-parts":[[2025,12]]},"published":{"date-parts":[[2025,11,8]]},"article-number":"ytaf581"}}