{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T17:36:50Z","timestamp":1765388210221,"version":"3.46.0"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T00:00:00Z","timestamp":1764374400000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Current guidelines recommend that patients with systolic heart failure should keep their resting heart rate (HR) at a relatively low level. However, the optimal HR level for patients with right-sided heart failure (RHF) remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>A 43-year-old male diagnosed with desmin-related cardiomyopathy 3 years ago has been repeatedly hospitalized over the past 5 months due to fatigue and severe oedema, with suboptimal control despite high-dose diuretic medication. This patient, with an average HR of 55\u201360 b.p.m., was implanted with a pacemaker adjusted at 90 b.p.m. on this admission. Right heart catheterization revealed immediate improvements in haemodynamics, including increased cardiac output and decreased vena cava pressure and right atrial pressure. At the 12-month follow-up, the patient was classified as New York Heart Association Class I and did not experience recurrence of oedema, even while taking low-dose diuretics (torasemide, 5\u2005mg once daily, and spironolactone, 20\u2005mg once daily).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>A previous study has shown that personalized acceleration of pacing rate in patients with heart failure with preserved ejection fraction can effectively improve quality of life. In addition, patients who undergo Fontan surgery can remain asymptomatic for decades, suggesting that left ventricular pump function may be sufficient to sustain both systemic and pulmonary circulation. Therefore, increasing HR can increase cardiac output, promote forward flow from the right atrium and vena cava into the pulmonary circulation, and reduce venous and right atrium pressures in patients with RHF and normal left-sided heart function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaf618","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T13:12:50Z","timestamp":1764335570000},"source":"Crossref","is-referenced-by-count":0,"title":["Permanent pacemaker implantation with high pacing rate for treating refractory right heart failure: a case report"],"prefix":"10.1093","volume":"9","author":[{"given":"Yanxing","family":"Fang","sequence":"first","affiliation":[{"name":"Department of Cardiology, Zhongshan Hospital, Fudan University , No. 180, Fenglin Road, Shanghai 200032 ,","place":["China"]},{"name":"National Clinical Research Center for Interventional Medicine , Zhongshan Hospital, Fudan University, No. 180, Fenglin Road, Shanghai 200032 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0530-261X","authenticated-orcid":false,"given":"Wenzhi","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Zhongshan Hospital, Fudan University , No. 180, Fenglin Road, Shanghai 200032 ,","place":["China"]},{"name":"National Clinical Research Center for Interventional Medicine , Zhongshan Hospital, Fudan University, No. 180, Fenglin Road, Shanghai 200032 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9926-5708","authenticated-orcid":false,"given":"Daxin","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Zhongshan Hospital, Fudan University , No. 180, Fenglin Road, Shanghai 200032 ,","place":["China"]},{"name":"National Clinical Research Center for Interventional Medicine , Zhongshan Hospital, Fudan University, No. 180, Fenglin Road, Shanghai 200032 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junbo","family":"Ge","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Zhongshan Hospital, Fudan University , No. 180, Fenglin Road, Shanghai 200032 ,","place":["China"]},{"name":"National Clinical Research Center for Interventional Medicine , Zhongshan Hospital, Fudan University, No. 180, Fenglin Road, Shanghai 200032 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,11,29]]},"reference":[{"key":"2025121012314795900_ytaf618-B1","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.1093\/eurheartj\/ehaf291","article-title":"Heart rate-lowering drugs and outcomes in hypertension and\/or cardiovascular disease: a meta-analysis","volume":"46","author":"Sanidas","year":"2025","journal-title":"Eur Heart J"},{"key":"2025121012314795900_ytaf618-B2","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/S0140-6736(10)61259-7","article-title":"Heart rate as a risk factor in chronic heart failure (SHIFT): the association between heart rate and outcomes in a randomised placebo-controlled trial","volume":"376","author":"B\u00f6hm","year":"2010","journal-title":"Lancet"},{"key":"2025121012314795900_ytaf618-B3","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.jacc.2020.11.022","article-title":"2021 update to the 2017 ACC expert consensus decision pathway for optimization of heart failure treatment: answers to 10 pivotal issues about heart failure with reduced ejection fraction: a report of the American College of Cardiology Solution Set Oversight Committee","volume":"77","author":"Writing Committee","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"2025121012314795900_ytaf618-B4","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1002\/ejhf.2206","article-title":"Patient profiling in heart failure for tailoring medical therapy. 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