{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T21:41:19Z","timestamp":1768858879377,"version":"3.49.0"},"reference-count":4,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T00:00:00Z","timestamp":1764374400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sarcoidosis is a great mimicker of various medical conditions, which leads to obstacles in early diagnosis and appropriate timely management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>A 66-year-old Indian female with metabolic syndrome was initially treated for decompensated liver disease. Her baseline electrocardiogram showed right bundle branch block with a first-degree heart block. She presented 3 months later with angina and heart failure (HF) symptoms, complicated with ventricular tachycardia (VT) treated with i.v. amiodarone and anti-failure medication. Her coronary angiogram revealed mild disease, and her echocardiography showed a mildly reduced ejection fraction (EF) of 45% with regional wall motion abnormalities. Cardiac magnetic resonance imaging (CMR) revealed non-specific left ventricular (LV) patchy mid-wall to epicardial late gadolinium enhancement. Endomyocardial biopsy was complicated with cardiac tamponade and required pericardiocentesis followed by dual-chamber implantable cardioverter-defibrillator (ICD) later. Unfortunately, biopsy result was inconclusive, and serum angiotensin-converting enzyme was within the normal range. She had multiple admissions for the past 2 years for recurrent VT and decompensated HF despite the optimization of ICD setting and guideline-directed medical therapy. Repeated echocardiogram revealed similar EF with thinning of the LV basal septal segment. Her positron emission tomography (PET) scan (Tc-99\u2005m) showed diffuse uptake at the LV myocardium and supraclavicular\/mediastinal\/abdominopelvic lymph nodes with a mismatch of fluorodeoxyglucose uptake at the basal\u2013inferolateral segment (non-specific). Lymph node biopsy revealed chronic non-caseating granulomatous inflammation. Clinical diagnosis of cardiac sarcoidosis was made based on a histologic diagnosis of extracardiac sarcoidosis with cardiomyopathy\/ventricular arrhythmia combined with PET\/CMR findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Cardiac sarcoidosis can have a myriad of symptoms, which may mimic several other disorders leading to a diagnostic challenge.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaf632","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T13:00:00Z","timestamp":1764334800000},"source":"Crossref","is-referenced-by-count":0,"title":["Heart in the crossfire, from epsilon to beyond: cardiac sarcoidosis\u2014a case report"],"prefix":"10.1093","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3343-8968","authenticated-orcid":false,"given":"Humaid","family":"Ali","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Universiti Kebangsaan Malaysia , Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000 ,","place":["Malaysia"]},{"name":"Department of Medicine, Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia , Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000 ,","place":["Malaysia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0778-0815","authenticated-orcid":false,"given":"Hamat Hamdi","family":"Che Hassan","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universiti Kebangsaan Malaysia , Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000 ,","place":["Malaysia"]},{"name":"Department of Medicine, Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia , Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000 ,","place":["Malaysia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0324-3951","authenticated-orcid":false,"given":"Mohd Shawal Faizal","family":"Mohamad","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universiti Kebangsaan Malaysia , Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000 ,","place":["Malaysia"]},{"name":"Department of Medicine, Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia , Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000 ,","place":["Malaysia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1547-5660","authenticated-orcid":false,"given":"Boon Cong","family":"Beh","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universiti Kebangsaan Malaysia , Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000 ,","place":["Malaysia"]},{"name":"Department of Medicine, Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia , Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000 ,","place":["Malaysia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,11,29]]},"reference":[{"key":"2026011903013530200_ytaf632-B1","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1093\/eurheartj\/ehae356","article-title":"Management of cardiac sarcoidosis","volume":"45","author":"Sharma","year":"2024","journal-title":"Eur Heart J"},{"key":"2026011903013530200_ytaf632-B2","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/j.cjco.2020.11.022","article-title":"Ten questions cardiologists should be able to answer about cardiac sarcoidosis: case-based approach and contemporary review","volume":"3","author":"Lemay","year":"2021","journal-title":"CJC Open"},{"key":"2026011903013530200_ytaf632-B3","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.3390\/jcm13061694","article-title":"Cardiac sarcoidosis\u2014diagnostic and therapeutic challenges","volume":"13","author":"Korthals","year":"2024","journal-title":"J Clin Med"},{"key":"2026011903013530200_ytaf632-B4","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1093\/eurheartj\/ehad067","article-title":"Cardiac sarcoidosis: phenotypes, diagnosis, treatment, and prognosis","volume":"44","author":"Lehtonen","year":"2023","journal-title":"Eur Heart J"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/advance-article-pdf\/doi\/10.1093\/ehjcr\/ytaf632\/65660661\/ytaf632.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/10\/1\/ytaf632\/65660661\/ytaf632.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/10\/1\/ytaf632\/65660661\/ytaf632.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T08:01:46Z","timestamp":1768809706000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytaf632\/8361733"}},"subtitle":[],"editor":[{"given":"Amir","family":"Khalifa","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Deborah","family":"Cosmi","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Marta","family":"Cvijic","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Deepti","family":"Ranganathan","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,11,29]]},"references-count":4,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1,6]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytaf632","relation":{},"ISSN":["2514-2119"],"issn-type":[{"value":"2514-2119","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,1]]},"published":{"date-parts":[[2025,11,29]]},"article-number":"ytaf632"}}