{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:04:55Z","timestamp":1769126695979,"version":"3.49.0"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Morquio syndrome (MPS IV) is a rare multi-systemic disorder with significant cardiovascular implications, including early-onset valvular disease. Due to the improved life expectancy, these patients could require complex interventional solutions such as TAVI-in-TAVI procedure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>We present the first reported case of a 65-year-old woman with Morquio syndrome undergoing a TAVI-in-TAVI procedure for structural degeneration of a prior transcatheter bioprosthetic valve. The procedure was technically challenging due to complex thoracic anatomy, small aortic annulus, and intermediate-risk of coronary obstruction. A self-expanding Evolut FX + valve were successfully implanted with favourable haemodynamic outcomes and no major complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case highlights the feasibility and importance of individualized planning in complex redo-TAVI interventions in patients with rare congenital disorders.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaf662","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T12:21:44Z","timestamp":1768220504000},"source":"Crossref","is-referenced-by-count":0,"title":["TAVI-in-TAVI in a patient with morquio syndrome: a case report"],"prefix":"10.1093","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-1067-0358","authenticated-orcid":false,"given":"Diana Xiao Lan","family":"Chin","sequence":"first","affiliation":[{"name":"Department of Cardiology, Interventional Cardiology Unit, San Camillo Hospital , Circ.ne Gianicolense 87, Rome 00152 ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2500-4966","authenticated-orcid":false,"given":"Gianantonio","family":"De Michele","sequence":"additional","affiliation":[{"name":"Department of Translational Medical Sciences; Division of Cardiology, University of Campania Luigi Vanvitelli, A.O.R.N. \u2018Sant'Anna & San Sebastiano\u2019 , Caserta 81100 ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davide","family":"Cristofani","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Anesthesiology and Intensive Care Unit, San Camillo Hospital , Rome 00152 ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"De Felice","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Interventional Cardiology Unit, San Camillo Hospital , Circ.ne Gianicolense 87, Rome 00152 ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"key":"2026011903443896700_ytaf662-B1","doi-asserted-by":"crossref","first-page":"e187436412308150","DOI":"10.2174\/18743641-v17-230822-2022-61","article-title":"A narrative review of morquio syndrome: mucopolysaccharidosis (MPS) type IV","volume":"17","author":"Robart","year":"2023","journal-title":"Open Ophthalmol J"},{"key":"2026011903443896700_ytaf662-B2","first-page":"59","article-title":"Mortality in patients with morquio syndrome a","volume":"15","author":"Lavery","year":"2015","journal-title":"JIMD Rep"},{"key":"2026011903443896700_ytaf662-B3","doi-asserted-by":"crossref","first-page":"931","DOI":"10.2174\/138920111795542615","article-title":"Mucopolysaccharidosis type IVA (Morquio A disease): clinical review and current 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J Case Rep"},{"key":"2026011903443896700_ytaf662-B7","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.jcin.2023.01.376","article-title":"Explant vs redo-TAVR after transcatheter valve failure: mid-term outcomes from the EXPLANTORREDO-TAVR international registry","volume":"16","author":"Tang","year":"2023","journal-title":"JACC Cardiovasc Interv"},{"key":"2026011903443896700_ytaf662-B8","doi-asserted-by":"crossref","first-page":"e129","DOI":"10.4244\/EIJ-D-19-01094","article-title":"TAVR-in-TAVR and coronary access: importance of preprocedural planning","volume":"16","author":"Tarantini","year":"2020","journal-title":"EuroIntervention"},{"key":"2026011903443896700_ytaf662-B9","doi-asserted-by":"crossref","first-page":"e330","DOI":"10.4244\/EIJ-D-22-01125","article-title":"Feasibility of redo-TAVI in self-expanding Evolut valves: a CT analysis from the Evolut Low Risk Trial substudy","volume":"19","author":"Grubb","year":"2023","journal-title":"EuroIntervention"},{"key":"2026011903443896700_ytaf662-B10","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1016\/j.jcin.2021.03.060","article-title":"Predictors and clinical impact of prosthesis-patient mismatch after self-expandable TAVR in small annuli","volume":"14","author":"Leone","year":"2021","journal-title":"JACC Cardiovasc Interv"},{"key":"2026011903443896700_ytaf662-B11","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.jcin.2018.01.273","article-title":"Incidence, predictors, and clinical impact of prosthesis-patient mismatch following transcatheter aortic valve replacement in Asian patients: the OCEAN-TAVI registry","volume":"11","author":"Miyasaka","year":"2018","journal-title":"JACC Cardiovasc Interv"}],"container-title":["European Heart Journal - Case 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