{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T07:30:27Z","timestamp":1769153427621,"version":"3.49.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:00:00Z","timestamp":1767830400000},"content-version":"vor","delay-in-days":7,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82300500"],"award-info":[{"award-number":["82300500"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Left bundle branch area pacing (LBBAP) is a physiological pacing strategy considered safe in non-obstructive hypertrophic cardiomyopathy (HCM). Its effect on left ventricular outflow tract (LVOT) obstruction in anatomically predisposed patients remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>A 76-year-old woman underwent LBBAP for atrioventricular nodal dysfunction. One week later, she developed chest pain and elevated troponin, despite unobstructed coronaries. Echocardiography revealed a resting LVOT gradient of 112.6\u2005mmHg. Bipolar low-voltage pacing worsened the gradient, while unipolar high-voltage pacing reduced it to 15\u2005mmHg, with symptom relief and improved global longitudinal strain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This case illustrates a rare interaction between pacing configuration and LVOT dynamics. It emphasizes the need to recognize pacing-induced obstruction, particularly in patients with septal hypertrophy or mitral anomalies, and to adjust programming accordingly.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaf677","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T12:31:50Z","timestamp":1767702710000},"source":"Crossref","is-referenced-by-count":0,"title":["Left ventricular outflow tract obstruction following left bundle branch area pacing: a case report"],"prefix":"10.1093","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-9237-7944","authenticated-orcid":false,"given":"Xiaoming","family":"Lian","sequence":"first","affiliation":[{"name":"Department of Cardiology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine , #1665 Kong Jiang Road, Shanghai 200092 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