{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T23:51:11Z","timestamp":1773877871645,"version":"3.50.1"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T00:00:00Z","timestamp":1773792000000},"content-version":"vor","delay-in-days":17,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Brugada syndrome (BrS) is an unusual cardiac channelopathy associated with an increased risk of ventricular fibrillation (VF) and sudden cardiac death (SCD), highlighting the critical importance of early diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>A 22-year-old male patient presented with recurrent episodes of syncope, palpitations, and dyspnoea. Initial electrocardiograms (ECGs) showing a Brugada Type 1 pattern were misinterpreted as incomplete right bundle branch blocks. The patient was erroneously diagnosed with epilepsy due to misinterpretation of his syncope episodes as seizures. After further investigations, including a propafenone provocation test and cardiac magnetic resonance imaging (MRI), BrS was confirmed. An electrophysiologic study showed no inducibility of ventricular tachycardia (VT) or VF, and a subcutaneous implantable cardioverter-defibrillator (S-ICD) was implanted for the prevention of SCD. The patient\u2019s recovery was successful and uncomplicated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Brugada syndrome patients usually present with SCD, syncope, or severe arrhythmias. Syncope is the most common clinical presentation and identifies patients who could benefit from ICD. Only the Type 1 Brugada pattern is diagnostic, either spontaneous, unmasked by high precordial leads, or by sodium channel inhibition. Implantable cardioverter-defibrillator placement is indicated to prevent SCD. A subcutaneous defibrillator should be considered if the patient has no need for anti-bradyarrhythmia pacing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Early recognition of BrS in patients with syncope is critical, especially for first-line providers interpreting ECGs, as it may prevent SCD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytag113","type":"journal-article","created":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T16:59:12Z","timestamp":1773853152000},"source":"Crossref","is-referenced-by-count":0,"title":["Unmasking Brugada syndrome: a case report of diagnostic oversights"],"prefix":"10.1093","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4271-7512","authenticated-orcid":false,"given":"Juan C","family":"Ibarrola-Pena","sequence":"first","affiliation":[{"name":"Tecnologico de monterrey, Escuela de Medicina y Ciencias de la Salud , Av Morones Prieto 3000, Monterrey, Nuevo Leon CP 64710 ,","place":["Mexico"]},{"name":"Instituto de Cardiolog\u00eda y Medicina Vascular, TecSalud, Escuela de Medicina y Ciencias de la Salud, Tecnol\u00f3gico de Monterrey , Batall\u00f3n de San Patricio 112, Real de San Agustin, San Pedro Garza Garcia, Nuevo Leon 66278 ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6627-8249","authenticated-orcid":false,"given":"Rafael","family":"Garcia-Ramos","sequence":"additional","affiliation":[{"name":"Tecnologico de monterrey, Escuela de Medicina y Ciencias de la Salud , Av Morones Prieto 3000, Monterrey, Nuevo Leon CP 64710 ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrique","family":"Paredes-Gutierrez","sequence":"additional","affiliation":[{"name":"Tecnologico de monterrey, Escuela de Medicina y Ciencias de la Salud , Av Morones Prieto 3000, Monterrey, Nuevo Leon CP 64710 ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerardo","family":"Pozas-Garza","sequence":"additional","affiliation":[{"name":"Tecnologico de monterrey, Escuela de Medicina y Ciencias de la Salud , Av Morones Prieto 3000, Monterrey, Nuevo Leon CP 64710 ,","place":["Mexico"]},{"name":"Instituto de Cardiolog\u00eda y Medicina Vascular, TecSalud, Escuela de Medicina y Ciencias de la Salud, Tecnol\u00f3gico de Monterrey , Batall\u00f3n de San Patricio 112, Real de San Agustin, San Pedro Garza Garcia, Nuevo Leon 66278 ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3123-9594","authenticated-orcid":false,"given":"Erasmo","family":"De la Pena-Almaguer","sequence":"additional","affiliation":[{"name":"Tecnologico de monterrey, Escuela de Medicina y Ciencias de la Salud , Av Morones Prieto 3000, Monterrey, Nuevo Leon CP 64710 ,","place":["Mexico"]},{"name":"Instituto de Cardiolog\u00eda y Medicina Vascular, TecSalud, Escuela de Medicina y Ciencias de la Salud, Tecnol\u00f3gico de Monterrey , Batall\u00f3n de San Patricio 112, Real de San Agustin, San Pedro Garza Garcia, Nuevo Leon 66278 ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,3,18]]},"reference":[{"key":"2026031812590885600_ytag113-B1","doi-asserted-by":"crossref","first-page":"1520008","DOI":"10.3389\/fphys.2024.1520008","article-title":"Brugada syndrome update","volume":"15","author":"Xu","year":"2025","journal-title":"Front Physiol"},{"key":"2026031812590885600_ytag113-B2","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.jacep.2021.12.001","article-title":"Brugada syndrome","volume":"8","author":"Krahn","year":"2022","journal-title":"JACC Clin Electrophysiol"},{"key":"2026031812590885600_ytag113-B3","doi-asserted-by":"crossref","first-page":"3997","DOI":"10.1093\/eurheartj\/ehac262","article-title":"2022 ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death","volume":"43","author":"Zeppenfeld","year":"2022","journal-title":"Eur Heart J"},{"key":"2026031812590885600_ytag113-B4","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1093\/europace\/euv278","article-title":"Expert cardiologists cannot distinguish between Brugada phenocopy and Brugada syndrome electrocardiogram patterns","volume":"18","author":"Gottschalk","year":"2016","journal-title":"Europace"},{"key":"2026031812590885600_ytag113-B5","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.hrthm.2016.12.004","article-title":"Late gadolinium enhancement in Brugada syndrome: a marker for subtle underlying cardiomyopathy?","volume":"14","author":"Bastiaenen","year":"2017","journal-title":"Heart Rhythm"},{"key":"2026031812590885600_ytag113-B6","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.cjco.2023.02.006","article-title":"Management of inherited arrhythmia syndromes: a HiRO consensus handbook on process of care","volume":"5","author":"Janzen","year":"2023","journal-title":"CJC Open"},{"key":"2026031812590885600_ytag113-B7","first-page":"1652","article-title":"Subcutaneous implantable cardioverter defibrillator: a contemporary overview","volume":"13","author":"Guarracini","year":"2023","journal-title":"Life (Basel)"},{"key":"2026031812590885600_ytag113-B8","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1093\/eurheartj\/ehl450","article-title":"Long-term follow-up of primary prophylactic implantable cardioverter-defibrillator therapy in Brugada syndrome","volume":"28","author":"Sarkozy","year":"2007","journal-title":"Eur Heart J"},{"key":"2026031812590885600_ytag113-B9","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.hrthm.2022.09.016","article-title":"Lights and shadows of subcutaneous implantable cardioverter-defibrillator in Brugada syndrome","volume":"20","author":"Dendramis","year":"2023","journal-title":"Heart Rhythm"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/10\/3\/ytag113\/67392126\/ytag113.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/10\/3\/ytag113\/67392126\/ytag113.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T16:59:13Z","timestamp":1773853153000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytag113\/8527844"}},"subtitle":[],"editor":[{"given":"Felix","family":"Wiedmann","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Melonie","family":"Johns","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Habib Rehman","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Deepti","family":"Ranganathan","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3,2]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytag113","relation":{},"ISSN":["2514-2119"],"issn-type":[{"value":"2514-2119","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,3]]},"published":{"date-parts":[[2026,3]]},"article-number":"ytag113"}}