{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T22:13:43Z","timestamp":1774390423072,"version":"3.50.1"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":12,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Systemic thrombolysis fails in around 8% of high-risk pulmonary embolism (PE) patients, and is associated with an increased risk of bleeding. Catheter-based aspirational thrombectomy (CAT) is emerging as a promising treatment option for PE, even when thrombolysis fails.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>A 47-year-old woman, with short bowel syndrome and a history of previous pulmonary embolism presents with acute chest pain and haemodynamic instability. CT angiography showed central pulmonary embolism, and the patient was initially treated with acute thrombolysis. Despite this, the patient remained haemodynamically unstable and developed a life-threatening retroperitoneal bleed originating from the left kidney. A multidisciplinary team discussion was held among a PE cardiologist, interventional cardiologist, interventional radiologist, and an intensive care specialist. As the patient was considered too unstable for surgery, an emergency percutaneous embolization of the left kidney combined with CAT was planned. The renal arterial angiography showed diffuse ongoing capsular bleeding and was successfully embolized with particles (EmboSphere 300\u2013500\u2005um) and two microcoils in the main renal artery. Thereafter, bilateral thrombectomy was performed using the AlphaVac\u00ae system, and several large thrombi were removed. The patient\u00b4s haemodynamic improved instantly, and she was discharged from the intensive care unit to the cardiac ward after 11 days.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>In this case, an acute and life-threatening complication to systemic thrombolysis was successfully managed with acute combined percutaneous embolization and thrombus aspiration. This procedure required careful planning and cooperation involving multiple specialties, emphasizing the importance of multi-disciplinary team discussions in the management of complex PE patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytag200","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T13:04:30Z","timestamp":1773234270000},"source":"Crossref","is-referenced-by-count":0,"title":["Combined pulmonary thrombectomy and kidney embolization as bailout to thrombolysis: a case report"],"prefix":"10.1093","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0929-8697","authenticated-orcid":false,"given":"Jens","family":"Tr\u00f8an","sequence":"first","affiliation":[{"name":"Department of Cardiology, Odense University Hospital , J. B. Winsl\u00f8ws Vej 4, 5000 Odense C ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin Kirk","family":"Christensen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Odense University Hospital , J. B. Winsl\u00f8ws Vej 4, 5000 Odense C ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikkel","family":"Taudorf","sequence":"additional","affiliation":[{"name":"Department of Radiology, Odense University Hospital , J. B. Winsl\u00f8ws Vej 4, 5000 Odense C ,","place":["Denmark"]},{"name":"Department of Radiology, Diagnostic Center, Copenhagen University Hospital - Rigshospitalet , Blegdamsvej 9, 2100 Copenhagen, Denmark"},{"name":"Dept of Clinical Medicine, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikkel","family":"Bak","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, Odense University Hospital , J. B. Winsl\u00f8ws Vej 4, 5000 Odense C ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikkel","family":"Hougaard","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Odense University Hospital , J. B. Winsl\u00f8ws Vej 4, 5000 Odense C ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"key":"2026032416022965300_ytag200-B1","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1093\/eurheartj\/ehz405","article-title":"2019 ESC guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): the task force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC)","volume":"41","author":"Konstantinides","year":"2019","journal-title":"Eur Heart J"},{"key":"2026032416022965300_ytag200-B2","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1378\/chest.129.4.1043","article-title":"Management of unsuccessful thrombolysis in acute massive pulmonary embolism","volume":"129","author":"Meneveau","year":"2006","journal-title":"Chest"},{"key":"2026032416022965300_ytag200-B3","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1093\/eurheartj\/ehu218","article-title":"Systemic thrombolytic therapy for acute pulmonary embolism: a systematic review and meta-analysis","volume":"36","author":"Marti","year":"2015","journal-title":"Eur Heart J"},{"key":"2026032416022965300_ytag200-B4","doi-asserted-by":"crossref","first-page":"e623","DOI":"10.4244\/EIJ-D-22-00246","article-title":"Percutaneous treatment options for acute pulmonary embolism: a clinical consensus statement by the ESC Working Group on Pulmonary Circulation and Right Ventricular Function and the European Association of Percutaneous Cardiovascular Interventions","volume":"18","author":"Pruszczyk","year":"2022","journal-title":"EuroIntervention"},{"key":"2026032416022965300_ytag200-B5","first-page":"102463","article-title":"Novel mechanical aspiration thrombectomy in patients with acute pulmonary embolism: results from the prospective APEX-AV trial","volume":"4","author":"Ranade","year":"2025","journal-title":"J Soc Cardiovasc Angiogr Interv"},{"key":"2026032416022965300_ytag200-B6","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.33963\/v.phj.102155","article-title":"Saddle thrombus transcatheter aspiration thrombectomy with novel large-bore AlphaVac device","volume":"82","author":"Araszkiewicz","year":"2024","journal-title":"Kardiol Pol"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/advance-article-pdf\/doi\/10.1093\/ehjcr\/ytag200\/67338879\/ytag200.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/10\/3\/ytag200\/67338879\/ytag200.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/10\/3\/ytag200\/67338879\/ytag200.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T20:02:33Z","timestamp":1774382553000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytag200\/8519175"}},"subtitle":[],"editor":[{"given":"Krishnaraj","family":"Rathod","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"A","family":"Ashika","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Hassan Ahmed Hassan","family":"Abdou","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Deepti","family":"Ranganathan","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3,2]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytag200","relation":{},"ISSN":["2514-2119"],"issn-type":[{"value":"2514-2119","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,3]]},"published":{"date-parts":[[2026,3]]},"article-number":"ytag200"}}