{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T21:06:51Z","timestamp":1779484011184,"version":"3.53.1"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T00:00:00Z","timestamp":1778457600000},"content-version":"vor","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Coronary artery aneurysms are uncommon and may present with acute coronary syndromes due to thrombotic complications. Giant coronary artery aneurysms, particularly involving the right coronary artery, pose significant diagnostic and therapeutic challenges, especially in young patients without traditional cardiovascular risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>We report the case of a 37-year-old previously healthy male who presented with sudden-onset severe chest pain and electrocardiographic findings consistent with inferior ST-segment elevation myocardial infarction. Emergency coronary angiography revealed a giant right coronary artery aneurysm measuring 16.9\u2005mm in maximal diameter and 33.5\u2005mm in length, with distal thrombotic occlusion. Thrombus aspiration restored normal coronary flow, and the patient was initially stable on intensive antithrombotic therapy.<\/jats:p>\n                    <jats:p>Twenty four hours later, he developed recurrent chest pain followed by cardiac arrest requiring prolonged cardiopulmonary resuscitation. Repeat angiography demonstrated re-occlusion of the right coronary artery due to extensive thrombosis. Repeat thrombus aspiration was performed, and intra-aortic balloon pump support was instituted. The post\u2013cardiac arrest course was complicated by transient multiorgan dysfunction, which gradually resolved with intensive supportive care.<\/jats:p>\n                    <jats:p>Extensive etiologic workup was unremarkable. Following a multidisciplinary Heart Team discussion, surgical revascularization was proposed but declined by the patient. He was managed conservatively with anticoagulation and single antiplatelet therapy. At the 3-month follow-up, coronary angiography demonstrated chronic total occlusion of the right coronary artery with complete thrombosis of the aneurysmal segment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Giant coronary artery aneurysms may remain clinically silent until catastrophic thrombotic events occur. This case highlights the limitations of medical therapy alone in preventing recurrent thrombosis and underscores the importance of individualized management, close follow-up, and multidisciplinary decision-making in this high-risk population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytag347","type":"journal-article","created":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T11:43:48Z","timestamp":1778240628000},"source":"Crossref","is-referenced-by-count":0,"title":["Giant right coronary artery aneurysm with recurrent thrombosis and cardiac arrest in a young adult: a case report"],"prefix":"10.1093","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0126-068X","authenticated-orcid":false,"given":"Hassan","family":"Elzain","sequence":"first","affiliation":[{"name":"Sudan Medical Specialization Board , Medical Department Hospital Street, Khartoum, 11111 ,","place":["Sudan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Alaa Eldean","family":"Shuggora","sequence":"additional","affiliation":[{"name":"Sudan Medical Specialization Board , Medical Department Hospital Street, Khartoum, 11111 ,","place":["Sudan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasem","family":"Redha","sequence":"additional","affiliation":[{"name":"Ministry of Health , Cardiology Department, Sulaibikhat, P.O. Box 5, Kuwait City 13001 ,","place":["Kuwait"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Adel","family":"Mostafa","sequence":"additional","affiliation":[{"name":"Ministry of Health , Cardiology Department, Sulaibikhat, P.O. Box 5, Kuwait City 13001 ,","place":["Kuwait"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anas Bedawi","family":"Babiker","sequence":"additional","affiliation":[{"name":"Royal Care International Hospital , Cardiology Department, Khartoum, Burri, 1330 \u00a0","place":["Sudan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,5,11]]},"reference":[{"key":"2026052216354355900_ytag347-B1","doi-asserted-by":"crossref","first-page":"24","DOI":"10.3389\/fcvm.2017.00024","article-title":"Coronary artery aneurysms: a review of the epidemiology, pathophysiology, diagnosis, and treatment","volume":"4","author":"Abou Sherif","year":"2017","journal-title":"Front Cardiovasc Med"},{"key":"2026052216354355900_ytag347-B2","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1161\/CIRCINTERVENTIONS.107.763656","article-title":"Giant coronary artery aneurysm: imaging findings before and after treatment with a polytetrafluoroethylene-covered stent","volume":"1","author":"Eshtehardi","year":"2008","journal-title":"Circ Cardiovasc Interv"},{"key":"2026052216354355900_ytag347-B3","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/j.jcin.2018.02.041","article-title":"Management of coronary artery aneurysms","volume":"11","author":"Kawsara","year":"2018","journal-title":"JACC Cardiovasc Interv"},{"key":"2026052216354355900_ytag347-B4","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1161\/01.CIR.67.1.134","article-title":"Aneurysmal coronary artery disease","volume":"67","author":"Swaye","year":"1983","journal-title":"Circulation"},{"key":"2026052216354355900_ytag347-B5","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0002-9149(76)90315-5","article-title":"Clinical significance of coronary arterial ectasia","volume":"37","author":"Markis","year":"1976","journal-title":"Am J Cardiol"},{"key":"2026052216354355900_ytag347-B6","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.jtcvs.2005.04.004","article-title":"Surgical treatment of giant coronary artery aneurysm","volume":"130","author":"Li","year":"2005","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2026052216354355900_ytag347-B7","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/eurheartj\/ehy394","article-title":"2018 ESC\/EACTS guidelines on myocardial revascularization","volume":"40","author":"Neumann","year":"2019","journal-title":"Eur Heart J"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/advance-article-pdf\/doi\/10.1093\/ehjcr\/ytag347\/68268694\/ytag347.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/10\/5\/ytag347\/68268694\/ytag347.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/10\/5\/ytag347\/68268694\/ytag347.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T20:35:54Z","timestamp":1779482154000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytag347\/8675961"}},"subtitle":[],"editor":[{"given":"Helle","family":"S\u00f8holm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Islam","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"A Shaheer","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Shaheen","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Dimitris","family":"Karelas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,4,30]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,4,30]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytag347","relation":{},"ISSN":["2514-2119"],"issn-type":[{"value":"2514-2119","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,5]]},"published":{"date-parts":[[2026,4,30]]},"article-number":"ytag347"}}