{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T19:00:35Z","timestamp":1780599635642,"version":"3.54.1"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:00:00Z","timestamp":1780531200000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Coronary embolism is a rare but clinically important non-atherosclerotic cause of acute myocardial infarction. Its diagnosis becomes especially challenging in young patients with mechanical valves, especially when the presentation follows blunt chest trauma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>A 24-year-old man with a mechanical aortic valve presented with progressive chest pain and dyspnoea 2 days after blunt chest trauma. Electrocardiography (ECG) demonstrated extensive anterior\u2013lateral ST-segment elevation myocardial infarction (STEMI). Transoesophageal echocardiography revealed normal prosthetic valve function, an apical aneurysm, and a non-mobile left ventricular (LV) mural thrombus. Coronary angiography showed a large thrombotic occlusion in the proximal left anterior descending (LAD) artery with otherwise normal coronary anatomy. Findings were most consistent with coronary embolism originating from a trauma-induced LV mural thrombus. Given the high thrombus burden, the patient received dual antiplatelet therapy, continued warfarin, and tirofiban infusion. Follow-up imaging confirmed complete resolution of the thrombus and improvement in ventricular function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This case illustrates the rare mechanism of trauma-induced LV mural thrombus embolization causing STEMI in a young prosthetic-valve patient. Integration of multimodality imaging coupled with meticulous clinical reasoning is required for systematic exclusion of spontaneous coronary artery dissection (SCAD), infective endocarditis, prosthetic-valve thrombosis, hypercoagulable states, and in situ coronary thrombosis to establish the true aetiology. Tirofiban may be an effective adjunct in high-burden embolic coronary occlusions when distal flow is preserved.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytag381","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T11:32:03Z","timestamp":1780399923000},"source":"Crossref","is-referenced-by-count":0,"title":["Trauma-triggered coronary embolism causing extensive anterolateral ST-segment elevation myocardial infarction in a young man with a mechanical aortic valve: a case report"],"prefix":"10.1093","volume":"10","author":[{"given":"Davar","family":"Aledavood","sequence":"first","affiliation":[{"name":"Department of Cardiology, Shiraz University of Medical Sciences , Shiraz 7134814336 ,","place":["Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Alizadeh","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Shiraz University of Medical Sciences , Shiraz 7134814336 ,","place":["Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4060-5593","authenticated-orcid":false,"given":"Mahsa","family":"Borjzadehgashtaseb","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Shiraz University of Medical Sciences , Shiraz 7134814336 ,","place":["Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,4]]},"reference":[{"key":"2026060414041025900_ytag381-B1","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.3390\/medicina61091615","article-title":"Myocardial infarction in young adults: revisiting risk factors and atherothrombotic pathways","volume":"61","author":"Cojocaru","year":"2025","journal-title":"Medicina"},{"key":"2026060414041025900_ytag381-B2","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.tcm.2022.07.004","article-title":"Coronary artery embolism and acute coronary syndrome: a critical appraisal of existing data","volume":"34","author":"Monin","year":"2024","journal-title":"Trends Cardiovasc Med"},{"key":"2026060414041025900_ytag381-B3","doi-asserted-by":"crossref","first-page":"113037","DOI":"10.1016\/j.jbiomech.2025.113037","article-title":"The effects of non-physiological shear rate gradient, frequency, and amplitude on platelet aggregation","volume":"194","author":"Yang","year":"2026","journal-title":"J Biomech"},{"key":"2026060414041025900_ytag381-B4","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.amjms.2016.12.010","article-title":"Myocardial infarction secondary to blunt chest trauma","volume":"355","author":"Marroush","year":"2018","journal-title":"Am J Med Sci"},{"key":"2026060414041025900_ytag381-B5","first-page":"12","article-title":"Cardiac trauma","volume":"8","author":"Long","year":"2019","journal-title":"Injury"},{"key":"2026060414041025900_ytag381-B6","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1378\/chest.63.4.628","article-title":"Ventricular aneurysms and blunt chest trauma","volume":"63","author":"Silver","year":"1973","journal-title":"Chest"},{"key":"2026060414041025900_ytag381-B7","first-page":"83","article-title":"Low dose Alteplase (rt-PA) in the management of mechanical prosthetic valve thrombosis A case series","volume":"6","author":"Seshagiri","year":"2022","journal-title":"IHJ Cardiovasc Case Rep"},{"key":"2026060414041025900_ytag381-B8","doi-asserted-by":"crossref","first-page":"e523","DOI":"10.1161\/CIR.0000000000000564","article-title":"Spontaneous coronary artery dissection: current state of the science: a scientific statement from the American Heart Association","volume":"137","author":"Hayes","year":"2018","journal-title":"Circulation"},{"key":"2026060414041025900_ytag381-B9","first-page":"1440","article-title":"NIRS-IVUS for differentiating coronary plaque rupture, erosion, and calcified nodule in acute myocardial infarction","volume":"14","author":"Terada","year":"2021","journal-title":"Cardiovasc Imaging"},{"key":"2026060414041025900_ytag381-B10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0133523","article-title":"Hypercoagulability is a stronger risk factor for ischaemic stroke than for myocardial infarction: a systematic review","volume":"10","author":"Maino","year":"2015","journal-title":"PLoS One"},{"key":"2026060414041025900_ytag381-B11","doi-asserted-by":"crossref","first-page":"724","DOI":"10.3949\/ccjm.76a.09062","article-title":"An algorithm for managing warfarin resistance","volume":"76","author":"Osinbowale","year":"2009","journal-title":"Cleve Clin J Med"},{"key":"2026060414041025900_ytag381-B12","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1002\/clc.20029","article-title":"Extensive myocardial infarction and left ventricular thrombus after chest collision during a soccer match","volume":"29","author":"Mohrs","year":"2006","journal-title":"Clin Cardiol"}],"container-title":["European Heart Journal - 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