{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:27:02Z","timestamp":1791070022935,"version":"4.1.0"},"reference-count":47,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,5,7]],"date-time":"2022-05-07T00:00:00Z","timestamp":1651881600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Underutilization of guideline-directed heart failure with reduced ejection fraction (HFrEF) medications contributes to poor outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>A pilot study to evaluate the safety and efficacy of a home-based remote monitoring system for HFrEF management was performed. The system included wearable armband monitors paired with the smartphone application. An HFrEF medication titration algorithm was used to adjust medication daily. The primary endpoint was HFrEF medication utilization at 120 days. Twenty patients (60.5\u2009\u00b1\u20098.2 years, men: 85%) with HFrEF were recruited. All received angiotensin-converting enzyme inhibitor (ACEI)\/angiotensin receptor blocker (ARB)\/angiotensin receptor-neprilysin inhibitor (ARNI) at recruitment; 45% received \u226550% maximal targeted dose (MTD) with % MTD of 44.4\u2009\u00b1\u200931.7%. At baseline, 90 and 70% received beta-adrenergic blocker and mineralocorticoid receptor antagonist (MRA), 35% received \u226550% MTD beta-adrenergic blocker with % MTD of 34.1\u2009\u00b1\u200929.6%, and 25% received \u226550% MTD MRA with % MTD of 25.0\u2009\u00b1\u200919.9%. At 120 days, 70% received \u226550% MTD ACEI\/ARB\/ARNI (P\u2009=\u20090.110) with % MTD increased to 64.4\u2009\u00b1\u200933.5% (P\u2009=\u20090.060). The proportion receiving \u226550% MTD ARNI increased from 15 to 55% (P\u2009=\u20090.089) with % MTD ARNI increased from 20.6\u2009\u00b1\u200930.9 to 53.1\u2009\u00b1\u200939.5% (P\u2009=\u20090.006*). More patients received \u226550% MTD MRA (65 vs. 25%, P\u2009=\u20090.011*) with % MTD MRA increased from 25.0\u2009\u00b1\u200919.9 to 46.2\u2009\u00b1\u200928.8% (P\u2009=\u20090.009*). Ninety-five per cent of patients had reduced NT-proBNP with the percentage reduction of 26.7\u2009\u00b1\u200919.7%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Heart failure with reduced ejection fraction medication escalation with remote monitoring appeared feasible.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjdh\/ztac024","type":"journal-article","created":{"date-parts":[[2022,5,7]],"date-time":"2022-05-07T10:05:39Z","timestamp":1651917939000},"page":"284-295","source":"Crossref","is-referenced-by-count":20,"title":["Daily ambulatory remote monitoring system for drug escalation in chronic heart failure with reduced ejection fraction: pilot phase of DAVID-HF study"],"prefix":"10.1093","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5205-9440","authenticated-orcid":false,"given":"Chun Ka","family":"Wong","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ka Chun","family":"Un","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi","family":"Zhou","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangyang","family":"Cheng","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuk Ming","family":"Lau","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puigi Catherine","family":"Shea","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hin Wai","family":"Lui","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming Liang","family":"Zuo","sequence":"additional","affiliation":[{"name":"Department of Echocardiography & Non-invasive Cardiology Laboratory, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital , Chengdu , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li Xue","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Echocardiography & Non-invasive Cardiology Laboratory, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital , Chengdu , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther W","family":"Chan","sequence":"additional","affiliation":[{"name":"Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian C K","family":"Wong","sequence":"additional","affiliation":[{"name":"Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon Wai Ching","family":"Sin","sequence":"additional","affiliation":[{"name":"Respiratory Division, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline Pui Ning","family":"Yeung","sequence":"additional","affiliation":[{"name":"Respiratory Division, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Chen","sequence":"additional","affiliation":[{"name":"Biofourmis Singapore Pte Ltd , Singapore , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandi","family":"Wibowo","sequence":"additional","affiliation":[{"name":"Biofourmis Singapore Pte Ltd , Singapore , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong Li Nikki","family":"Wei","sequence":"additional","affiliation":[{"name":"Biofourmis Singapore Pte Ltd , Singapore , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sze Ming","family":"Lee","sequence":"additional","affiliation":[{"name":"Harmony Medical Inc. , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Augustine","family":"Chow","sequence":"additional","affiliation":[{"name":"Harmony Medical Inc. , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond Cheuk Fung","family":"Tong","sequence":"additional","affiliation":[{"name":"Harmony Medical Inc. , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jojo","family":"Hai","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frankie Chor Cheung","family":"Tam","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung Wah","family":"Siu","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,5,7]]},"reference":[{"key":"2022121509082950700_ztac024-B1","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1093\/eurjhf\/hfs105","article-title":"ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC","volume":"14","author":"McMurray","year":"2012","journal-title":"Eur J Heart Fail"},{"key":"2022121509082950700_ztac024-B2","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.ijcard.2016.07.256","article-title":"Heart failure across Asia: same healthcare burden but differences in organization of care","volume":"223","author":"Reyes","year":"2016","journal-title":"Int J Cardiol"},{"key":"2022121509082950700_ztac024-B3","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1056\/NEJM199108013250501","article-title":"Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure","volume":"325","author":"The SOLVD Investigators","year":"1991","journal-title":"N Engl J Med"},{"key":"2022121509082950700_ztac024-B4","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1056\/NEJM198706043162301","article-title":"Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)","volume":"316","author":"The CONSENSUS Trial Study Group","year":"1987","journal-title":"N Engl J Med"},{"key":"2022121509082950700_ztac024-B5","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0140-6736(98)11181-9","article-title":"The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial","volume":"353","year":"1999","journal-title":"Lancet"},{"key":"2022121509082950700_ztac024-B6","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1001\/jama.283.10.1295","article-title":"Effects of controlled-release metoprolol on total mortality, hospitalizations, and well-being in patients with heart failure: the Metoprolol CR\/XL Randomized Intervention Trial in congestive heart failure (MERIT-HF)","volume":"283","author":"Hjalmarson","year":"2000","journal-title":"JAMA"},{"key":"2022121509082950700_ztac024-B7","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1016\/S0140-6736(99)04440-2","article-title":"Effect of metoprolol CR\/XL in chronic heart failure: Metoprolol CR\/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)","volume":"353","year":"1999","journal-title":"Lancet"},{"key":"2022121509082950700_ztac024-B8","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa1009492","article-title":"Eplerenone in patients with systolic heart failure and mild symptoms","volume":"364","author":"Zannad","year":"2011","journal-title":"N Engl J Med"},{"key":"2022121509082950700_ztac024-B9","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1056\/NEJM199909023411001","article-title":"The effect of spironolactone on morbidity and mortality in patients with severe heart failure","volume":"341","author":"Pitt","year":"1999","journal-title":"N Engl J Med"},{"key":"2022121509082950700_ztac024-B10","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/S0140-6736(10)61198-1","article-title":"Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study","volume":"376","author":"Swedberg","year":"2010","journal-title":"Lancet"},{"key":"2022121509082950700_ztac024-B11","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1056\/NEJMoa1409077","article-title":"Angiotensin-neprilysin inhibition versus enalapril in heart failure","volume":"371","author":"McMurray","year":"2014","journal-title":"N Engl J Med"},{"key":"2022121509082950700_ztac024-B12","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1056\/NEJMoa2022190","article-title":"Cardiovascular and renal outcomes with empagliflozin in heart failure","volume":"383","author":"Packer","year":"2020","journal-title":"N Engl J Med"},{"key":"2022121509082950700_ztac024-B13","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1056\/NEJMoa1911303","article-title":"Dapagliflozin in patients with heart failure and reduced ejection fraction","volume":"381","author":"McMurray","year":"2019","journal-title":"N Engl J Med"},{"key":"2022121509082950700_ztac024-B14","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1093\/eurjhf\/hfq002","article-title":"Characteristics, outcomes, and predictors of mortality at 3 months and 1 year in patients hospitalized for acute heart failure","volume":"12","author":"Harjola","year":"2010","journal-title":"Eur J Heart Fail"},{"key":"2022121509082950700_ztac024-B15","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1253\/circj.CJ-09-0254","article-title":"Characteristics and outcomes of hospitalized patients with heart failure and reduced vs preserved ejection fraction. Report from the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)","volume":"73","author":"Tsuchihashi-Makaya","year":"2009","journal-title":"Circ J"},{"key":"2022121509082950700_ztac024-B16","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1253\/circj.CJ-11-1093","article-title":"Treatment performance measures affect clinical outcomes in patients with acute systolic heart failure: report from the Korean Heart Failure Registry","volume":"76","author":"Youn","year":"2012","journal-title":"Circ J"},{"key":"2022121509082950700_ztac024-B17","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.cardfail.2016.03.007","article-title":"Clinical characteristics, management, and outcomes of hospitalized heart failure in a Chinese population-the Hong Kong heart failure registry","volume":"22","author":"Hai","year":"2016","journal-title":"J Card Fail"},{"key":"2022121509082950700_ztac024-B18","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.jchf.2018.11.011","article-title":"Target doses of heart failure medical therapy and blood pressure: insights from the CHAMP-HF registry","volume":"7","author":"Peri-Okonny","year":"2019","journal-title":"JACC Heart Fail"},{"key":"2022121509082950700_ztac024-B19","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1002\/ejhf.510","article-title":"Physicians\u2019 adherence to guideline-recommended medications in heart failure with reduced ejection fraction: data from the QUALIFY global survey","volume":"18","author":"Komajda","year":"2016","journal-title":"Eur J Heart Fail"},{"key":"2022121509082950700_ztac024-B20","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.jacc.2012.03.023","article-title":"Relationship of beta-blocker dose with outcomes in ambulatory heart failure patients with systolic dysfunction: results from the HF-ACTION (Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training) trial","volume":"60","author":"Fiuzat","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"2022121509082950700_ztac024-B21","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1161\/01.CIR.100.23.2312","article-title":"Comparative effects of low and high doses of the angiotensin-converting enzyme inhibitor, lisinopril, on morbidity and mortality in chronic heart failure","volume":"100","author":"Packer","year":"1999","journal-title":"Circulation"},{"key":"2022121509082950700_ztac024-B22","doi-asserted-by":"crossref","first-page":"2807","DOI":"10.1161\/01.CIR.94.11.2807","article-title":"Carvedilol produces dose-related improvements in left ventricular function and survival in subjects with chronic heart failure","volume":"94","author":"Bristow","year":"1996","journal-title":"Circulation"},{"key":"2022121509082950700_ztac024-B23","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.jacc.2017.04.025","article-title":"2017 ACC\/AHA\/HFSA focused update of the 2013 ACCF\/AHA guideline for the management of heart failure: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America","volume":"70","author":"Yancy","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2022121509082950700_ztac024-B24","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1002\/ejhf.592","article-title":"2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC","volume":"18","author":"Ponikowski","year":"2016","journal-title":"Eur J Heart Fail"},{"key":"2022121509082950700_ztac024-B25","doi-asserted-by":"crossref","first-page":"2301","DOI":"10.1056\/NEJMoa1010029","article-title":"Telemonitoring in patients with heart failure","volume":"363","author":"Chaudhry","year":"2010","journal-title":"N Engl J Med"},{"key":"2022121509082950700_ztac024-B26","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1056\/NEJMc1100395","article-title":"Telemonitoring in patients with heart failure","volume":"364","author":"Swedberg","year":"2011","journal-title":"N Engl J Med"},{"key":"2022121509082950700_ztac024-B27","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1056\/NEJMc1100395","article-title":"Telemonitoring in patients with heart failure","volume":"364","author":"Inglis","year":"2011","journal-title":"N Engl J Med"},{"key":"2022121509082950700_ztac024-B28","first-page":"1079","article-title":"Telemonitoring in patients with heart failure","volume":"364","author":"Everett","year":"2011","journal-title":"N Engl J Med"},{"key":"2022121509082950700_ztac024-B29","doi-asserted-by":"crossref","first-page":"4388","DOI":"10.1038\/s41598-021-82771-7","article-title":"Observational study on wearable biosensors and machine learning-based remote monitoring of COVID-19 patients","volume":"11","author":"Un","year":"2021","journal-title":"Sci Rep"},{"key":"2022121509082950700_ztac024-B30","doi-asserted-by":"crossref","first-page":"e038555","DOI":"10.1136\/bmjopen-2020-038555","article-title":"Artificial intelligence mobile health platform for early detection of COVID-19 in quarantine subjects using a wearable biosensor: protocol for a randomised controlled trial","volume":"10","author":"Wong","year":"2020","journal-title":"BMJ Open"},{"key":"2022121509082950700_ztac024-B31","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1136\/heartjnl-2018-313147","article-title":"Diagnostic assessment of a deep learning system for detecting atrial fibrillation in pulse waveforms","volume":"104","author":"Poh","year":"2018","journal-title":"Heart"},{"key":"2022121509082950700_ztac024-B32","doi-asserted-by":"crossref","DOI":"10.1093\/eurheartj\/ehw128","article-title":"2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC","author":"Ponikowski","year":"2016","journal-title":"Eur Heart J"},{"key":"2022121509082950700_ztac024-B33","first-page":"3243","article-title":"Biovitals: a personalized multivariate physiology analytics using continuous mobile biosensors","volume":"2019","author":"Chen","year":"2019","journal-title":"Annu Int Conf IEEE Eng Med Biol Soc"},{"key":"2022121509082950700_ztac024-B34","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1136\/heartjnl-2021-319229","article-title":"Heart failure medication dosage and survival in women and men seen at outpatient clinics","volume":"107","author":"Bots","year":"2021","journal-title":"Heart"},{"key":"2022121509082950700_ztac024-B35","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1161\/CIRCULATIONAHA.106.184461","article-title":"Assessment of functional capacity in clinical and research settings: a scientific statement from the American Heart Association Committee on Exercise, Rehabilitation, and Prevention of the Council on Clinical Cardiology and the Council on Cardiovascular Nursing","volume":"116","author":"Arena","year":"2007","journal-title":"Circulation"},{"key":"2022121509082950700_ztac024-B36","doi-asserted-by":"crossref","first-page":"e12122","DOI":"10.2196\/12122","article-title":"Use of free-living step count monitoring for heart failure functional classification: validation study","volume":"3","author":"Baril","year":"2019","journal-title":"JMIR Cardio"},{"key":"2022121509082950700_ztac024-B37","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1093\/eurheartj\/ehs104","article-title":"ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC","volume":"33","author":"McMurray","year":"2012","journal-title":"Eur Heart J"},{"key":"2022121509082950700_ztac024-B38","doi-asserted-by":"crossref","first-page":"7","DOI":"10.15420\/cfr.2016:25:2","article-title":"Global public health burden of heart failure","volume":"3","author":"Savarese","year":"2017","journal-title":"Card Fail Rev"},{"key":"2022121509082950700_ztac024-B39","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/S0140-6736(11)60101-3","article-title":"Wireless pulmonary artery haemodynamic monitoring in chronic heart failure: a randomised controlled trial","volume":"377","author":"Abraham","year":"2011","journal-title":"Lancet"},{"key":"2022121509082950700_ztac024-B40","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0140-6736(15)00723-0","article-title":"Sustained efficacy of pulmonary artery pressure to guide adjustment of chronic heart failure therapy: complete follow-up results from the CHAMPION randomised trial","volume":"387","author":"Abraham","year":"2016","journal-title":"Lancet"},{"key":"2022121509082950700_ztac024-B41","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1177\/1357633X18774632","article-title":"Long-term impact of a six-month telemedical care programme on mortality, heart failure readmissions and healthcare costs in patients with chronic heart failure","volume":"25","author":"Frederix","year":"2019","journal-title":"J Telemed Telecare"},{"key":"2022121509082950700_ztac024-B42","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1177\/1357633X15600583","article-title":"Impact on clinical events and healthcare costs of adding telemedicine to multidisciplinary disease management programmes for heart failure: results of a randomized controlled trial","volume":"22","author":"Comin-Colet","year":"2016","journal-title":"J Telemed Telecare"},{"key":"2022121509082950700_ztac024-B43","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1111\/jgs.13432","article-title":"Efficacy of a physician-led multiparametric telemonitoring system in very old adults with heart failure","volume":"63","author":"Pedone","year":"2015","journal-title":"J Am Geriatr Soc"},{"key":"2022121509082950700_ztac024-B44","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.cardfail.2007.10.014","article-title":"Managing heart failure care using an internet-based telemedicine system","volume":"14","author":"Kashem","year":"2008","journal-title":"J Card Fail"},{"key":"2022121509082950700_ztac024-B45","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1177\/2047487316671438","article-title":"Prognostic value of serial six-minute walk tests using tele-accelerometry in patients with chronic heart failure: a pre-specified sub-study of the TIM-HF-Trial","volume":"23","author":"Prescher","year":"2016","journal-title":"Eur J Prev Cardiol"},{"key":"2022121509082950700_ztac024-B46","doi-asserted-by":"crossref","first-page":"4723","DOI":"10.1016\/j.ijcard.2013.07.171","article-title":"Tele-accelerometry as a novel technique for assessing functional status in patients with heart failure: feasibility, reliability and patient safety","volume":"168","author":"Jehn","year":"2013","journal-title":"Int J Cardiol"},{"key":"2022121509082950700_ztac024-B47","doi-asserted-by":"crossref","first-page":"e006513","DOI":"10.1161\/CIRCHEARTFAILURE.119.006513","article-title":"Continuous wearable monitoring analytics predict heart failure hospitalization: the LINK-HF multicenter study","volume":"13","author":"Stehlik","year":"2020","journal-title":"Circ Heart Fail"}],"container-title":["European Heart Journal - Digital Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjdh\/advance-article-pdf\/doi\/10.1093\/ehjdh\/ztac024\/43905289\/ztac024.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjdh\/article-pdf\/3\/2\/284\/47905939\/ztac024.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjdh\/article-pdf\/3\/2\/284\/47905939\/ztac024.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T16:50:08Z","timestamp":1671123008000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjdh\/article\/3\/2\/284\/6582292"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,7]]},"references-count":47,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,5,7]]},"published-print":{"date-parts":[[2022,7,6]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjdh\/ztac024","relation":{},"ISSN":["2634-3916"],"issn-type":[{"value":"2634-3916","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,6,22]]},"published":{"date-parts":[[2022,5,7]]}}}