{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:04:11Z","timestamp":1787061851556,"version":"build-2736575974"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T00:00:00Z","timestamp":1726617600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005416","name":"Research Council of Norway","doi-asserted-by":"publisher","award":["296570"],"award-info":[{"award-number":["296570"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Norwegian Association for Children with Congenital Heart Disease","award":["133"],"award-info":[{"award-number":["133"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>New three-dimensional cardiac visualization technologies are increasingly employed for anatomic digital twins in pre-operative planning. However, the role and influence of extended reality (virtual, augmented, or mixed) within heart team settings remain unclear. We aimed to assess the impact of mixed reality visualization of the intracardiac anatomy on surgical decision-making in patients with complex heart defects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>Between September 2020 and December 2022, we recruited 50 patients and generated anatomic digital twins and visualized them in mixed reality. These anatomic digital twins were presented to the heart team after initial decisions were made using standard visualization methods. Changes in the surgical strategy were recorded. Additionally, heart team members rated their mixed reality experience through a questionnaire, and post-operative outcomes were registered. Anatomic digital twins changed the initially decided upon surgical strategies for 68% of cases. While artificial intelligence facilitated the rapid creation of digital anatomic twins, manual corrections were always necessary.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In conclusion, mixed reality anatomic digital twins added information to standard visualization methods and significantly influenced surgical planning, with evidence that these strategies can be implemented safely without additional risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjdh\/ztae070","type":"journal-article","created":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T16:34:08Z","timestamp":1726504448000},"page":"725-734","source":"Crossref","is-referenced-by-count":18,"title":["Cardiac anatomic digital twins: findings from a single national centre"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0259-292X","authenticated-orcid":false,"given":"Matthias","family":"Lippert","sequence":"first","affiliation":[{"name":"The Intervention Centre, Division for Technology and Innovation, Oslo University Hospital, Rikshospitalet , PO Box 4950 Nydalen, Oslo 0424 ,","place":["Norway"]},{"name":"Institute of Clinical Medicine, University of Oslo, Kirkeveien 166, Oslo 0450, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl-Andreas","family":"Dumont","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Oslo University Hospital , Oslo ,","place":["Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sigurd","family":"Birkeland","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Oslo University Hospital , Oslo ,","place":["Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varatharajan","family":"Nainamalai","sequence":"additional","affiliation":[{"name":"The Intervention Centre, Division for Technology and Innovation, Oslo University Hospital, Rikshospitalet , PO Box 4950 Nydalen, Oslo 0424 ,","place":["Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e5vard","family":"Solvin","sequence":"additional","affiliation":[{"name":"The Intervention Centre, Division for Technology and Innovation, Oslo University Hospital, Rikshospitalet , PO Box 4950 Nydalen, Oslo 0424 ,","place":["Norway"]},{"name":"Institute of Clinical Medicine, University of Oslo, Kirkeveien 166, Oslo 0450, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrine Ryd\u00e9n","family":"Suther","sequence":"additional","affiliation":[{"name":"Department of Radiology, Division of Radiology and Nuclear Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1392-6481","authenticated-orcid":false,"given":"Bj\u00f8rn","family":"Bendz","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, University of Oslo, Kirkeveien 166, Oslo 0450, Norway"},{"name":"Department of Cardiology, Oslo University Hospital , Oslo ,","place":["Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole Jakob","family":"Elle","sequence":"additional","affiliation":[{"name":"The Intervention Centre, Division for Technology and Innovation, Oslo University Hospital, Rikshospitalet , PO Box 4950 Nydalen, Oslo 0424 ,","place":["Norway"]},{"name":"Department of Informatics, University of Oslo , Oslo ,","place":["Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Brun","sequence":"additional","affiliation":[{"name":"The Intervention Centre, Division for Technology and Innovation, Oslo University Hospital, Rikshospitalet , PO Box 4950 Nydalen, Oslo 0424 ,","place":["Norway"]},{"name":"Department for Pediatric Cardiology, Oslo University Hospital , Oslo ,","place":["Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,9,18]]},"reference":[{"key":"2024111804035673400_ztae070-B1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s41205-016-0004-x","article-title":"3D printing in medicine of congenital heart diseases","volume":"2","author":"Yoo","year":"2015","journal-title":"3D Print Med"},{"key":"2024111804035673400_ztae070-B2","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1161\/CIRCULATIONAHA.114.012033","article-title":"Achievements in congenital heart defect surgery: a prospective, 40-year study of 7038 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