{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T16:28:03Z","timestamp":1793291283586,"version":"4.5.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T00:00:00Z","timestamp":1713398400000},"content-version":"vor","delay-in-days":108,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>End-stage renal disease (ESRD) patients are prone to alterations in cardiac haemodynamics specifically on the left ventricle (LV) and left atrial (LA) functions usually due to factors like uraemia, fluid overload, and inflammation. While studies on LV function in ESRD exist, research on LA function is limited. Successful kidney transplant (KTx) is believed to reverse pathological cardiac remodelling, and monitoring changes in cardiac strain before and after transplantation may guide pre- and post-transplant care. This study has two main objectives: to investigate alterations in LA and LV strain and other echocardiographic parameters after KTx and to identify independent factors predicting impaired strain parameters post-KTx.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>We conducted a prospective cohort study of 49 ESRD patients who underwent KTx. Echocardiography was performed at baseline and at 3 months after KTx. LV end-diastolic volume, LV end-systolic volume, LV end-diastolic diameter, LV ejection fraction (LVEF), E\/e\u2032, maximum LA volume index (LAVi), LV global longitudinal strain (LVGLS), and all LA strain values, including booster (LASb), conduit (LAScd), and reservoir (LASr), improved significantly after KTx (P &amp;lt; 0.05). Regarding independent predictors of impaired LA and LV strains, pre-KTx values of LVEF, LAVi, and NT-proBNP were associated with LVGLS impairment after KTx; pre-KTx values of LAVi and LVEF were associated with LASr impairment after KTx.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>The present study provided valuable evidence on the effects of KTx on uraemic cardiomyopathy demonstrated by LA strain and LV strain improvements and indicated pre-KTx LVEF and LAVi as significant independent predictors of LVGLS and LASr impairment after KTx.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjimp\/qyae027","type":"journal-article","created":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T22:26:52Z","timestamp":1713479212000},"source":"Crossref","is-referenced-by-count":4,"title":["Left atrial and ventricular deformation: alterations and predictive value of echocardiography parameters in end-stage renal disease patients after kidney transplantation"],"prefix":"10.1093","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5269-142X","authenticated-orcid":false,"given":"Abdulhamid","family":"Bagheri","sequence":"first","affiliation":[{"name":"Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences , Velenjak, Tajrish, Arabi ave, Bldg No. 2, 7th floor, P.O. BOX: 19615-1178 , Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Khani","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences , Velenjak, Tajrish, Arabi ave, Bldg No. 2, 7th floor, P.O. BOX: 19615-1178 , Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3903-0464","authenticated-orcid":false,"given":"Erfan","family":"Ghadirzadeh","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Mazandaran University of Medical Sciences , Sari , Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Moradi","sequence":"additional","affiliation":[{"name":"Atherosclerosis Research Center, Jundishapur University of Medical Sciences , Ahvaz , Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8485-2072","authenticated-orcid":false,"given":"Fariba","family":"Bayat","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences , Velenjak, Tajrish, Arabi ave, Bldg No. 2, 7th floor, P.O. BOX: 19615-1178 , Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7172-2321","authenticated-orcid":false,"given":"Seyed Pooria","family":"Salehi Mashhad Sari","sequence":"additional","affiliation":[{"name":"Student Research Committee, Golestan University of Medical Sciences , Gorgan , Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5692-067X","authenticated-orcid":false,"given":"Elham","family":"Paraandavaji","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences , Velenjak, Tajrish, Arabi ave, Bldg No. 2, 7th floor, P.O. 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(CKD) stage 2\u20135 with preserved ejection fraction (EF): a systematic review to explore CKD stage-wise LVH patterns","volume":"48","author":"Maqbool","year":"2023","journal-title":"Curr Probl Cardiol"},{"key":"2024071810123906100_qyae027-B6","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1111\/tri.13152","article-title":"Regression of left atrial diameter after kidney transplantation is associated with prolonged survival: an observational study","volume":"31","author":"Regele","year":"2018","journal-title":"Transpl Int"},{"key":"2024071810123906100_qyae027-B7","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1053\/j.ajkd.2017.11.018","article-title":"Pulmonary hypertension, mortality, and cardiovascular disease in CKD and ESRD patients: a systematic review and meta-analysis","volume":"72","author":"Tang","year":"2018","journal-title":"Am J Kidney 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