{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:18:55Z","timestamp":1787498335067,"version":"build-2736575974"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T00:00:00Z","timestamp":1717977600000},"content-version":"vor","delay-in-days":161,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["20dz1207200"],"award-info":[{"award-number":["20dz1207200"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["KC22247"],"award-info":[{"award-number":["KC22247"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Recent studies have shown that extracellular volume (ECV) can also be obtained without blood sampling by the linear relationship between haematocrit (HCT) and blood pool R1 (1\/T1). However, whether this relationship holds for patients with myocardial infarction is still unclear. This study established and validated an ECV model without blood sampling in ST-segment elevation myocardial infarction (STEMI) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>A total of 398 STEMI patients who underwent cardiac magnetic resonance (CMR) examination with T1 mapping and venous HCT within 24\u2005h were retrospectively analysed. All patients were randomly divided into a derivation group and a validation group. The mean CMR scan time was 3\u2005days after primary percutaneous coronary intervention. In the derivation group, a synthetic HCT formula was obtained by the linear regression between HCT and blood pool R1 (R2 = 0.45, P &amp;lt; 0.001). The formula was used in the validation group; the results showed high concordance and correlation between synthetic ECV and conventional ECV in integral (bias = \u22120.12; R2 = 0.92, P &amp;lt; 0.001), myocardial infarction site (bias = \u22120.23; R2 = 0.93, P &amp;lt; 0.001), and non-myocardial infarction sites (bias = \u22120.09; R2 = 0.94, P &amp;lt; 0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In STEMI patients, synthetic ECV without blood sampling had good consistency and correlation with conventional ECV. This study might provide a convenient and accurate method to obtain the ECV from CMR to identify myocardial fibrosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjimp\/qyae053","type":"journal-article","created":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T08:29:22Z","timestamp":1718008162000},"source":"Crossref","is-referenced-by-count":3,"title":["Establishment and validation of an extracellular volume model without blood sampling in ST-segment elevation myocardial infarction patients"],"prefix":"10.1093","volume":"2","author":[{"given":"Lei","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Cardiology, Shanghai Tenth People\u2019s Hospital, Tongji University School of Medicine , 301 Yanchang Road, Shanghai 200072 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeqing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The Affiliated Hospital of Xuzhou Medical University , 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