{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T23:10:47Z","timestamp":1789686647469,"version":"4.0.1"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T00:00:00Z","timestamp":1749772800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009779","name":"Region Kronoberg","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009779","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008810","name":"New South Wales Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008810","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009021","name":"Heart Research Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009021","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001774","name":"University of Sydney","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001774","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003793","name":"Swedish Heart-Lung Foundation","doi-asserted-by":"publisher","award":["20160787"],"award-info":[{"award-number":["20160787"]}],"id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003793","name":"Swedish Heart-Lung Foundation","doi-asserted-by":"publisher","award":["20200160"],"award-info":[{"award-number":["20200160"]}],"id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"publisher","award":["2019-01338"],"award-info":[{"award-number":["2019-01338"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>A quantitative estimate of pulmonary artery wedge pressure (PAWP) can be obtained using echocardiography, but including left atrial (LA) volume (ePAWP-LA) in the estimation may be misleading. We aimed to derive and validate a new estimate without LA volume information (ePAWP-NOLA) and compare its performance to the ASE\/EACVI algorithms for diastolic dysfunction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>ePAWP-NOLA was derived and validated in separate datasets of patients who had undergone right heart catheterization and echocardiography. The prognosis was assessed in the validation cohort and the National Echocardiography Database Australia (NEDA) using Cox regression adjusted for age, sex, and left ventricular ejection fraction (LVEF). In the derivation cohort (60 \u00b1 15 years, 40% males, 31% with LVEF &amp;lt; 50%), ePAWP-NOLA was derived from mitral (E), and pulmonary vein systolic (S) and diastolic (D) Doppler velocities (n = 134, mean difference \u00b1 SD vs. PAWP: 0.0 \u00b1 5.5\u2005mmHg). In the validation cohort (n = 116, 51 \u00b1 14 years, 69% males, 89% with LVEF &amp;lt; 50%), PAWP agreed with both ePAWP-NOLA and ePAWP-LA (difference 1.3 \u00b1 6.1, 3.2 \u00b1 6.3\u2005mmHg, respectively). PAWP &amp;gt; 15\u2005mmHg was accurately detected by both ePAWP-NOLA and ePAWP-LA [area under the curve: AUC (95%CI): 0.84 (0.76\u20130.92), 0.80 (0.72\u20130.88)]. AUC for the ASE\/EACVI algorithm was lower [0.69 (0.61\u20130.77)]). ePAWP-NOLA and ePAWP-LA correlated with right ventricular afterload and were associated with death or implantation of left ventricular assist device, and with cardiovascular death in NEDA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>ePAWP-NOLA has diagnostic and prognostic performance comparable to ePAWP-LA, and improved diagnostic performance compared to the ASE\/EACVI diastolic dysfunction algorithm.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjimp\/qyaf082","type":"journal-article","created":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T07:48:05Z","timestamp":1749714485000},"source":"Crossref","is-referenced-by-count":1,"title":["Echocardiography can accurately estimate pulmonary artery wedge pressure without left atrial volume information\u2014diagnostic and prognostic performance"],"prefix":"10.1093","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2943-0034","authenticated-orcid":false,"given":"Thomas","family":"Lindow","sequence":"first","affiliation":[{"name":"Department of Pulmonary Medicine, Allergology, and Palliative Medicine, Clinical Sciences, Lund University , Box 117, 221 00 Lund ,","place":["Sweden"]},{"name":"Department of Clinical Physiology, Department of Research and Development, Region Kronoberg, V\u00e4xj\u00f6 Central Hospital , 351 88 V\u00e4xj\u00f6 ,","place":["Sweden"]},{"name":"Kolling Institute, Royal North Shore Hospital, and University of Sydney , St Leonards, Sydney, New South Wales 2065 ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6617-2070","authenticated-orcid":false,"given":"Aristomenis","family":"Manouras","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Unit of Heart Failure, Arrhythmia and GUCH, Karolinska University Hospital, Stockholm ,","place":["Sweden"]},{"name":"Department of Medicine, Karolinska Institutet , Solna ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6800-7119","authenticated-orcid":false,"given":"Geoff","family":"Strange","sequence":"additional","affiliation":[{"name":"School of Medicine , University of Notre Dame, Fremantle, Western Australia,","place":["Australia"]},{"name":"Faculty of Medicine and Health, University of Sydney , Sydney, New South Wales ,","place":["Australia"]},{"name":"Department of Cardiology, Royal Prince Alfred Hospital , Sydney, New South Wales ,","place":["Australia"]},{"name":"Heart Research Institute , Sydney, New South Wales ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4529-181X","authenticated-orcid":false,"given":"Per","family":"Lindqvist","sequence":"additional","affiliation":[{"name":"Departments of Diagnostics and Intervention, Clinical Physiology, Ume\u00e5 University , Ume\u00e5 ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4492-1103","authenticated-orcid":false,"given":"David","family":"Playford","sequence":"additional","affiliation":[{"name":"School of Medicine , University of Notre Dame, Fremantle, Western Australia,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9572-9819","authenticated-orcid":false,"given":"Odd","family":"Bech-Hanssen","sequence":"additional","affiliation":[{"name":"Department of Clinical Physiology, Sahlgrenska University Hospital , Gothenburg ,","place":["Sweden"]},{"name":"Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg , Gothenburg ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3665-2038","authenticated-orcid":false,"given":"Martin","family":"Ugander","sequence":"additional","affiliation":[{"name":"Kolling Institute, Royal North Shore Hospital, and University of Sydney , St Leonards, Sydney, New South Wales 2065 ,","place":["Australia"]},{"name":"Department of Clinical Physiology, Karolinska University Hospital, and Karolinska Institutet , Stockholm ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,6,13]]},"reference":[{"key":"2025070121313166000_qyaf082-B1","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.3390\/jcm8091331","article-title":"Right heart catheterization-background, physiological basics, and clinical 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