{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T11:07:42Z","timestamp":1785150462393,"version":"3.55.0"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"vor","delay-in-days":24,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["220703\/Z\/20\/Z"],"award-info":[{"award-number":["220703\/Z\/20\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["215799\/Z\/19\/Z"],"award-info":[{"award-number":["215799\/Z\/19\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000274","name":"British Heart Foundation Chair","doi-asserted-by":"publisher","award":["CH\/16\/2\/32089"],"award-info":[{"award-number":["CH\/16\/2\/32089"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Leeds Clinical Research Facility"},{"DOI":"10.13039\/501100018955","name":"Leeds Biomedical Research Centre","doi-asserted-by":"publisher","award":["NIHR203331"],"award-info":[{"award-number":["NIHR203331"]}],"id":[{"id":"10.13039\/501100018955","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Cardiovascular magnetic resonance (CMR)-derived pulmonary capillary wedge pressure (PCWP) has demonstrated diagnostic and prognostic utility in heart failure patients. However, its clinical value in acute myocardial infarction (AMI) remains undetermined. This study investigates the relationship between CMR-derived PCWP, myocardial injury, and left ventricular (LV) remodelling in re-perfused acute ST-elevation myocardial infarction (STEMI).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Sixty-nine patients with STEMI underwent CMR within 48 h and at 3\u2005months. PCWP was estimated using the sex-specific equation: CMR PCWP: 5.7591 + (0.07505 \u00d7 left atrial volume) [0.05289 \u00d7 left ventricular mass (LVM)] \u2212 (1.9927 \u00d7 sex) [female = 0; male = 1], where LAV is left atrial volume (mL) and LVM is left ventricular mass (g). LV remodelling was assessed via changes in LV end-diastolic volume (LVEDV) and ejection fraction (LVEF). Patients with high CMR PCWP (\u226518\u2005mmHg) exhibited greater myocardial scar burden (28.5% vs. 17.2%, P = 0.0008) and microvascular obstruction (7.6% vs. 2.5%, P &amp;lt; 0.0001). They also had higher acute LVEDV (193.7 \u00b1 39.7 vs. 158.0 \u00b1 29.5\u2005mL, P &amp;lt; 0.0001) and lower LVEF (41.4 \u00b1 10.4% vs. 48.5 \u00b1 9.2%, P = 0.0066). At follow-up, higher baseline CMR PCWP was associated with greater LV remodelling (P &amp;lt; 0.0001) and persistently reduced LVEF (45.4 \u00b1 10.2% vs. 55.0 \u00b1 10.3%, P = 0.0005). Regression analysis confirmed baseline PCWP as an independent predictor of follow-up LVEF (P = 0.0036).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>CMR-derived PCWP may be a valuable biomarker in STEMI, identifying patients at risk of adverse remodelling and LV dysfunction. Its integration into clinical practice may enhance risk stratification and guide targeted therapies.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjimp\/qyaf086","type":"journal-article","created":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T01:23:11Z","timestamp":1753406591000},"source":"Crossref","is-referenced-by-count":1,"title":["Haemodynamic implications of cardiovascular magnetic resonance pulmonary capillary wedge pressure in acute myocardial infarction"],"prefix":"10.1093","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5483-169X","authenticated-orcid":false,"given":"Pankaj","family":"Garg","sequence":"first","affiliation":[{"name":"The Bob Champion Research & Education Building, Rosalind Franklin Road, University of East Anglia , Norwich NR4 7UQ ,","place":["UK"]},{"name":"Cardiology Department, Colney Lane, Norfolk and Norwich University Teaching Hospitals , Norwich NR4 7UY ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3984-5005","authenticated-orcid":false,"given":"Aradhai","family":"Bana","sequence":"additional","affiliation":[{"name":"The Bob Champion Research & Education Building, Rosalind Franklin Road, University of East Anglia , Norwich NR4 7UQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8353-4806","authenticated-orcid":false,"given":"Gareth","family":"Matthews","sequence":"additional","affiliation":[{"name":"The Bob Champion Research & Education Building, Rosalind Franklin Road, University of East Anglia , Norwich NR4 7UQ ,","place":["UK"]},{"name":"Cardiology Department, Colney Lane, Norfolk and Norwich University Teaching Hospitals , Norwich NR4 7UY ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiya","family":"Bali","sequence":"additional","affiliation":[{"name":"The Bob Champion Research & Education Building, Rosalind Franklin Road, University of East Anglia , Norwich NR4 7UQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Li","sequence":"additional","affiliation":[{"name":"The Bob Champion Research & Education Building, Rosalind Franklin Road, University of East Anglia , Norwich NR4 7UQ ,","place":["UK"]},{"name":"Cardiology Department, Colney Lane, Norfolk and Norwich University Teaching Hospitals , Norwich NR4 7UY ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zia","family":"Mehmood","sequence":"additional","affiliation":[{"name":"The Bob Champion Research & Education Building, Rosalind Franklin Road, University of East Anglia , Norwich NR4 7UQ ,","place":["UK"]},{"name":"Cardiology Department, Colney Lane, Norfolk and Norwich University Teaching Hospitals , Norwich NR4 7UY 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