{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T06:56:27Z","timestamp":1789541787033,"version":"build-2803163510"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"vor","delay-in-days":19,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Clinical evaluation of congestion and perfusion in acute heart failure (AHF) has recognized limitations. Ultrasound tools such as the Venous Excess Ultrasound Score (VExUS) and the left ventricular outflow tract velocity\u2013time integral (LVOT VTI) have gained increasing support for bedside haemodynamic profiling. We assessed the incremental prognostic value of a combined VTI\u2013VExUS classification compared with standard clinical assessment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>We prospectively enrolled adults admitted with AHF. Within 24\u2005h of presentation, VExUS (congestion) and LVOT VTI (perfusion) were assessed and integrated into four ultrasound-based profiles. The primary endpoint was a 30-day composite of all-cause mortality, cardiogenic shock, mechanical ventilation, short-term ventricular assist device use, and inotropic\/vasopressor therapy. Among 167 patients (mean age 58.2 \u00b1 13.4 years; 72% male), event rates increased across VTI\u2013VExUS profiles (11.3%, 34.6%, 32.4%, and 69.2%, P &amp;lt; 0.001). Discrimination was superior for the VTI\u2013VExUS model vs. clinical assessment alone (AUC 0.74 vs. 0.58, P = 0.0016). Integrated discrimination improvement confirmed the added prognostic contribution (IDI 0.157, P = 0.004). Ultrasound profiles were independently associated with outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>VTI\u2013VExUS ultrasound profiling provides significant incremental prognostic information beyond clinical assessment in AHF. These findings support its role as a complementary bedside tool for early risk stratification.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjimp\/qyag012","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T09:25:18Z","timestamp":1768901118000},"source":"Crossref","is-referenced-by-count":3,"title":["Integrated ultrasound haemodynamic profiling (VTI\u2013VExUS) for risk stratification in acute heart failure"],"prefix":"10.1093","volume":"4","author":[{"given":"Omar Ivan","family":"Ruiz-Fuentes","sequence":"first","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez , Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan, Mexico City 14030 ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Barron-Martinez","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez , Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan, Mexico City 14030 ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eder","family":"Gonzalez-Macedo","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez , Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan, Mexico City 14030 ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9sus Antonio","family":"Viana-Rojas","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez , Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan, Mexico City 14030 ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Sierra-Gonzalez de Cossio","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez , Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan, Mexico City 14030 ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Gopar-Nieto","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez , Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan, Mexico City 14030 ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Alexandra","family":"Arias-Mendoza","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez , Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan, Mexico City 14030 ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge Daniel","family":"Sierra-Lara Martinez","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez , Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan, Mexico City 14030 ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge A","family":"Ortega-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez , Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan, Mexico City 14030 ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6975-8026","authenticated-orcid":false,"given":"Diego","family":"Araiza-Garaygordobil","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez , Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan, Mexico City 14030 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