{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T15:52:34Z","timestamp":1781970754495,"version":"3.54.5"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:00:00Z","timestamp":1774396800000},"content-version":"vor","delay-in-days":249,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Congenitally corrected transposition of the great arteries (ccTGA) is a rare congenital heart defect characterized by atrioventricular and ventriculoarterial discordance and frequently associated with heterogeneous anatomical anomalies. This variability makes surgical indication and strategy particularly complex, requiring accurate preoperative anatomical and functional assessment. We report four paediatric patients with complex ccTGA who underwent anatomical repair at our institution between July 2022 and March 2024. Associated findings included dextrocardia, situs inversus, ventricular septal defects, pulmonary outflow tract obstruction, and atrioventricular valve abnormalities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>All patients underwent stepwise multimodal imaging. Transthoracic echocardiography was complemented by cardiovascular magnetic resonance (CMR) to assess ventricular volumes and function, septal defects, outflow tract relationships, and systemic and pulmonary venous return. CMR datasets were processed to generate patient-specific virtual and 3D-printed models through dedicated segmentation, preserving real anatomical dimensions. These models were used for surgical simulation and multidisciplinary planning. Integration of CMR and 3D modelling directly influenced operative strategy in all cases. 3D reconstructions refined ventricular septal defect tunnelling towards the aorta, optimized ventriculotomy site selection, clarified atrial switch configuration, and anticipated the need for pulmonary root translocation. Anatomical repair was successfully achieved in all four patients, with no early mortality and preserved biventricular function at short follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Structured integration of CMR and patient-specific 3D modelling enhances spatial understanding and supports individualized surgical planning in complex ccTGA. Incorporating advanced imaging into routine clinical workflow represents a valuable strategy to improve precision and decision-making in anatomically challenging congenital heart disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjimp\/qyag052","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T12:34:39Z","timestamp":1774355679000},"source":"Crossref","is-referenced-by-count":0,"title":["Unveiling ccTGA complexity: CMR and 3D modelling for surgical planning\u2014a case series"],"prefix":"10.1093","volume":"3","author":[{"given":"Irene","family":"Cao","sequence":"first","affiliation":[{"name":"Department of Paediatric and Congenital Cardiology and Cardiac Surgery, Fondazione Toscana \u2018G. Monasterio\u2019, Heart Hospital of Massa , via Aurelia sud, 54100 Massa ,","place":["Italy"]},{"name":"Department of Paediatric and Congenital Cardiac Surgery, University of Padova , Padova ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7954-6302","authenticated-orcid":false,"given":"Vera","family":"Cetera","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Congenital Cardiology and Cardiac Surgery, Fondazione Toscana \u2018G. Monasterio\u2019, Heart Hospital of Massa , via Aurelia sud, 54100 Massa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaia","family":"Vigan\u00f2","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Congenital Cardiology and Cardiac Surgery, Fondazione Toscana \u2018G. Monasterio\u2019, Heart Hospital of Massa , via Aurelia sud, 54100 Massa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Marrone","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Congenital Cardiology and Cardiac Surgery, Fondazione Toscana \u2018G. Monasterio\u2019, Heart Hospital of Massa , via Aurelia sud, 54100 Massa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Torracchi","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Congenital Cardiology and Cardiac Surgery, Fondazione Toscana \u2018G. Monasterio\u2019, Heart Hospital of Massa , via Aurelia sud, 54100 Massa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Poli","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Congenital Cardiology and Cardiac Surgery, Fondazione Toscana \u2018G. Monasterio\u2019, Heart Hospital of Massa , via Aurelia sud, 54100 Massa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Celi","sequence":"additional","affiliation":[{"name":"BioCardioLab, Bioengineering Unit, Fondazione Toscana \u2018G. Monasterio\u2019, Heart Hospital of Massa , Massa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katia","family":"Capellini","sequence":"additional","affiliation":[{"name":"BioCardioLab, Bioengineering Unit, Fondazione Toscana \u2018G. Monasterio\u2019, Heart Hospital of Massa , Massa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0122-5175","authenticated-orcid":false,"given":"Emanuele","family":"Gasparotti","sequence":"additional","affiliation":[{"name":"BioCardioLab, Bioengineering Unit, Fondazione Toscana \u2018G. Monasterio\u2019, Heart Hospital of Massa , Massa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2430-6480","authenticated-orcid":false,"given":"Massimiliano","family":"Cantinotti","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Congenital Cardiology and Cardiac Surgery, Fondazione Toscana \u2018G. Monasterio\u2019, Heart Hospital of Massa , via Aurelia sud, 54100 Massa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Monteleone","sequence":"additional","affiliation":[{"name":"Department of Radiology and Diagnostic Imaging, Fondazione Toscana \u2018G. Monasterio\u2019, Heart Hospital of Massa , Massa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierluigi","family":"Festa","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Congenital Cardiology and Cardiac Surgery, Fondazione Toscana \u2018G. Monasterio\u2019, Heart Hospital of Massa , via Aurelia sud, 54100 Massa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lamia","family":"Ait-Ali","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Congenital Cardiology and Cardiac Surgery, Fondazione Toscana \u2018G. Monasterio\u2019, Heart Hospital of Massa , via Aurelia sud, 54100 Massa ,","place":["Italy"]},{"name":"Institute of Clinical Physiology, National Research Council (NRC) , Massa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitali","family":"Pak","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Congenital Cardiology and Cardiac Surgery, Fondazione Toscana \u2018G. Monasterio\u2019, Heart Hospital of Massa , via Aurelia sud, 54100 Massa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,3,25]]},"reference":[{"key":"2026062011413104900_qyag052-B1","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1161\/CIRCIMAGING.114.002277","article-title":"Congenitally corrected transposition of the great arteries: situs solitus or inversus","volume":"7","author":"Mah","year":"2014","journal-title":"Circ Cardiovasc Imaging"},{"key":"2026062011413104900_qyag052-B2","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1136\/heartjnl-2016-311032","article-title":"Contemporary management and outcomes in congenitally corrected transposition of the great 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