{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T03:11:59Z","timestamp":1793502719153,"version":"4.5.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T00:00:00Z","timestamp":1695340800000},"content-version":"vor","delay-in-days":21,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,9,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Many historical and recent reports showed that post-infarction ventricular septal rupture (VSR) represents a life-threatening condition and the strategy to optimally manage it remains undefined. Therefore, disparate treatment policies among different centres with variable results are often described. We analysed data from European centres to capture the current clinical practice in VSR management.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Thirty-nine centres belonging to eight European countries participated in a survey, filling a digital form of 38 questions from April to October 2022, to collect information about all the aspects of VSR treatment. Most centres encounter 1\u20135 VSR cases\/year. Surgery remains the treatment of choice over percutaneous closure (71.8% vs. 28.2%). A delayed repair represents the preferred approach (87.2%). Haemodynamic conditions influence the management in almost all centres, although some try to achieve patients stabilization and delayed surgery even in cardiogenic shock. Although 33.3% of centres do not perform coronarography in unstable patients, revascularization approaches are widely variable. Most centres adopt mechanical circulatory support (MCS), mostly extracorporeal membrane oxygenation, especially pre-operatively to stabilize patients and achieve delayed repair. Post-operatively, such MCS are more often adopted in patients with ventricular dysfunction.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In real-life, delayed surgery, regardless of the haemodynamic conditions, is the preferred strategy for VSR management in Europe. Extracorporeal membrane oxygenation is becoming the most frequently adopted MCS as bridge-to-operation. This survey provides a useful background to develop dedicated, prospective studies to strengthen the current evidence on VSR treatment and to help improving its currently unsatisfactory outcomes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjopen\/oead091","type":"journal-article","created":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T06:14:30Z","timestamp":1695449670000},"source":"Crossref","is-referenced-by-count":11,"title":["The current clinical practice for management of post-infarction ventricular septal rupture: a European survey"],"prefix":"10.1093","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5250-1796","authenticated-orcid":false,"given":"Daniele","family":"Ronco","sequence":"first","affiliation":[{"name":"Congenital Cardiac Surgery Department, IRCCS Policlinico San Donato , San Donato Milanese , Italy"},{"name":"Department of Cardiothoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre , Maastricht , The Netherlands"},{"name":"Thoracic Research Centre, Collegium Medicum Nicolaus Copernicus University, Innovative Medical Forum , Bydgoszcz , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Ariza-Sol\u00e9","sequence":"additional","affiliation":[{"name":"Cardiology Department, Bellvitge University Hospital , Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariusz","family":"Kowalewski","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre , Maastricht , The Netherlands"},{"name":"Thoracic Research Centre, Collegium Medicum Nicolaus Copernicus University, Innovative Medical Forum , Bydgoszcz , Poland"},{"name":"Department of Cardiac Surgery and Transplantology, Central Clinical Hospital of the Ministry of Interior, Centre of Postgraduate Medical Education , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Matteucci","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre , Maastricht , The Netherlands"},{"name":"Thoracic Research Centre, Collegium Medicum Nicolaus Copernicus University, Innovative Medical Forum , Bydgoszcz , Poland"},{"name":"Cardiac Surgery Unit, ASST dei Sette Laghi, Department of Medicine and Surgery, University of Insubria , Varese , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2611-5626","authenticated-orcid":false,"given":"Michele","family":"Di Mauro","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre , Maastricht , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esteban","family":"L\u00f3pez-de-S\u00e1","sequence":"additional","affiliation":[{"name":"Department of Cardiology, IDIPAZ, Hospital Universitario La Paz , Madrid , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4915-3572","authenticated-orcid":false,"given":"Marco","family":"Ranucci","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Anesthesia and Intensive Care, IRCCS Policlinico San Donato , San Donato Milanese , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0843-9512","authenticated-orcid":false,"given":"Alessandro","family":"Sionis","sequence":"additional","affiliation":[{"name":"Intensive Cardiac Care Unit, Cardiology Department, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau , Barcelona , Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Cardiovasculares, Instituto de Salud Carlos III , Madrid , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7656-5812","authenticated-orcid":false,"given":"Nikolaos","family":"Bonaros","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Medical University of Innsbruck , Innsbruck , Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9329-7437","authenticated-orcid":false,"given":"Michele","family":"De Bonis","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, San Raffaele University Hospital , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio Francesco","family":"Russo","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit, Cardio-Thoraco-Vascular Department, Niguarda Hospital , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6911-7480","authenticated-orcid":false,"given":"Aitor","family":"Uribarri","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Cardiovasculares, Instituto de Salud Carlos III , Madrid , Spain"},{"name":"Department of Cardiology, Instituto de Ciencias del Coraz\u00f3n (ICICOR), Hospital Cl\u00ednico Universitario de Valladolid , Valladolid , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0984-3472","authenticated-orcid":false,"given":"Santiago","family":"Montero","sequence":"additional","affiliation":[{"name":"Acute Cardiovascular Care Unit, Cardiology, Hospital Germans Trias i Pujol, Universitat Aut\u00f2noma de Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9781-3590","authenticated-orcid":false,"given":"Theodor","family":"Fischlein","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Cardiovascular Center, Klinikum N\u00fcrnberg, Paracelsus Medical University , Nuremberg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Kowal\u00f3wka","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Medical University of Silesia, School of Medicine in Katowice , Katowice , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiho","family":"Naito","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart & Vascular Center Hamburg , Hamburg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Fran\u00e7ois","family":"Obadia","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Louis Pradel Cardiologic Hospital , Lyon , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Mart\u00edn-Asenjo","sequence":"additional","affiliation":[{"name":"Intensive Cardiac Care Unit, Cardiology Department, Hospital Universitario 12 de Octubre and Instituto de Investigaci\u00f3n Sanitaria Hospital 12 de Octubre , Madrid , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime","family":"Aboal","sequence":"additional","affiliation":[{"name":"Cardiology Department, Hospital Josep Trueta , Girona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1007-2871","authenticated-orcid":false,"given":"Matthias","family":"Thielmann","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, West-German Heart and Vascular Center Essen, University Duisburg-Essen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Simon","sequence":"additional","affiliation":[{"name":"Cardiovascular and Transplant Department, Papa Giovanni XXIII Hospital , Bergamo , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rut","family":"Andrea-Riba","sequence":"additional","affiliation":[{"name":"Acute Cardiac Care Unit, Cardiology Department, Hospital Cl\u00ednic, IDIBAPS, Universitat de Barcelona , Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Parra","sequence":"additional","affiliation":[{"name":"Cardiology Department, Hospital Universitario Puerta de Hierro-Majadahonda , Madrid , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0009-6543","authenticated-orcid":false,"given":"Thierry","family":"Folliguet","sequence":"additional","affiliation":[{"name":"Department of Cardio-Thoracic Surgery, University Hospital Henri-Mondor, Assistance Publique\u2013Hopitaux de Paris Cr\u00e9teil , Paris , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Mart\u00ednez-Sell\u00e9s","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital General Universitario Gregorio Mara\u00f1on, CIBERCV, and Universidad Europea, Universidad Complutense , Madrid , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Sanmart\u00edn Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Cardiology Department, Hospital Ram\u00f3n y Cajal , Madrid , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nawwar","family":"Al-Attar","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Golden Jubilee National Hospital , Glasgow , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Viana Tejedor","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Instituto Cardiovascular, Hospital Universitario Cl\u00ednico San Carlos , Madrid , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe Filiberto","family":"Serraino","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, \u2018Magna Graecia\u2019 University of Catanzaro , Catanzaro , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia","family":"Burgos Palacios","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Universitario Marqu\u00e9s de Valdecilla , 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