{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T14:49:13Z","timestamp":1790952553935,"version":"4.1.0"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T00:00:00Z","timestamp":1713398400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004046","name":"Karen Elise Jensens Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004046","id-type":"DOI","asserted-by":"publisher"}]},{"name":"the Helse Foundation","award":["20-B-0155"],"award-info":[{"award-number":["20-B-0155"]}]},{"name":"Aarhus University Hospital Research Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>We aimed to investigate the influence of socioeconomic position (SEP) and multimorbidity on cross-sectional healthcare utilization and prognosis in patients after cardiac resynchronization therapy (CRT) implantation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>We included first-time CRT recipients with left ventricular ejection fraction \u226435% implanted between 2000 and 2017. Data on chronic conditions, use of healthcare services, and demographics were obtained from Danish national administrative and health registries. Healthcare utilization (in- and outpatient hospitalizations, activities in general practice) was compared by multimorbidity categories and SEP by using a negative binomial regression model. The association between SEP, multimorbidity, and prognostic outcomes was analysed using Cox proportional hazards regression. We followed 2007 patients (median age of 70 years), 79% were male, 75% were on early retirement or state pension, 37% were living alone, and 41% had low education level for a median of 5.2 [inter-quartile range: 2.2\u20137.3) years. In adjusted regression models, a higher number of chronic conditions were associated with increased healthcare utilization. Both cardiovascular and non-cardiovascular hospital contacts were increased. Patients with low SEP had a higher number of chronic conditions, but SEP had limited influence on healthcare utilization. Patients living alone and those with low educational level had a trend towards a higher risk of all-cause mortality [adjusted hazard ratio (aHR): 1.17, 95% confidence interval (CI) 1.03\u20131.33, and aHR 1.09, 95% CI 0.96\u20131.24).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Multimorbidity increased the use of cross-sectional healthcare services, whereas low SEP had minor influence on the utilizations. Living alone and low educational level showed a trend towards a higher risk of mortality after CRT implantation.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjopen\/oeae029","type":"journal-article","created":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T12:12:22Z","timestamp":1713442342000},"source":"Crossref","is-referenced-by-count":1,"title":["Influence of multimorbidity and socioeconomic position on long-term healthcare utilization and prognosis in patients after cardiac resynchronization therapy implantation"],"prefix":"10.1093","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1439-4624","authenticated-orcid":false,"given":"Christoffer Tobias","family":"Witt","sequence":"first","affiliation":[{"name":"Department of Cardiology, Aarhus University Hospital , Palle Juul-Jensens Boulevard 99, 8200 Aarhus N , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rikke Elmose","family":"Mols","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Aarhus University Hospital , Palle Juul-Jensens Boulevard 99, 8200 Aarhus N , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3281-5338","authenticated-orcid":false,"given":"Istv\u00e1n","family":"Bakos","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology, Aarhus University Hospital and Aarhus University , Olof Palmes All\u00e9 43-45, 8200 Aarhus N , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3594-2212","authenticated-orcid":false,"given":"Erzs\u00e9bet","family":"Horv\u00e1th-Puh\u00f3","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology, Aarhus University Hospital and Aarhus University , Olof Palmes All\u00e9 43-45, 8200 Aarhus N , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Christensen","sequence":"additional","affiliation":[{"name":"Department of Public Health, Research Unit for General Practice , Aarhus University Bartholins All\u00e9 2, 8000 Aarhus C , Denmark"},{"name":"Department of Clinical Medicine, Aarhus University , Palle Juul-Jensens Boulevard 82, 8200 Aarhus N , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian Bridal","family":"L\u00f8gstrup","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Aarhus University Hospital , Palle Juul-Jensens Boulevard 99, 8200 Aarhus N , Denmark"},{"name":"Department of Clinical Medicine, Aarhus University , Palle Juul-Jensens Boulevard 82, 8200 Aarhus N , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0631-0010","authenticated-orcid":false,"given":"Jens Cosedis","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Aarhus University Hospital , Palle Juul-Jensens Boulevard 99, 8200 Aarhus N , Denmark"},{"name":"Department of Clinical Medicine, Aarhus University , Palle Juul-Jensens Boulevard 82, 8200 Aarhus N , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1520-1924","authenticated-orcid":false,"given":"Hans","family":"Eiskj\u00e6r","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Aarhus University Hospital , Palle Juul-Jensens Boulevard 99, 8200 Aarhus N , Denmark"},{"name":"Department of Clinical Medicine, Aarhus University , Palle Juul-Jensens Boulevard 82, 8200 Aarhus N , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,4,18]]},"reference":[{"key":"2024062813164077500_oeae029-B1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0140-6736(12)60240-2","article-title":"Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study","volume":"380","author":"Barnett","year":"2012","journal-title":"Lancet"},{"key":"2024062813164077500_oeae029-B2","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1093\/ageing\/afw044","article-title":"Associations between multimorbidity, healthcare utilisation and health status: evidence from 16 European countries","volume":"45","author":"Palladino","year":"2016","journal-title":"Age Ageing"},{"key":"2024062813164077500_oeae029-B3","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1093\/europace\/euac123","article-title":"EHRA expert consensus document on the 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