{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T18:50:46Z","timestamp":1764874246471,"version":"build-2065373602"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:00:00Z","timestamp":1761523200000},"content-version":"vor","delay-in-days":59,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010661","name":"Horizon 2020","doi-asserted-by":"publisher","award":["945260"],"award-info":[{"award-number":["945260"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Older patients with AF (\u226565\u2005years) have on average four additional comorbidities. Comorbidity management requires a systematic approach for identification, and interdisciplinary care, often lacking in clinical practice. The EHRA-PATHS project\u2019s overall aim is to create an approach to systematically address multimorbidity in older patients with AF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>This project involves a consortium of 14 partners from 11 European countries. The comorbidity care pathways were developed using a stepwise approach. (i) A literature study. (ii) Online meetings\/discussions to create structured care pathways. (iii) A two-round Delphi study for consensus on the final pathways (agreement \u226580%) and to rank the comorbidities for priority. (iv) Selection of comorbidities for evaluation in the planned randomized controlled trial (RCT). Development of care pathways for 23 comorbidities or special clinical settings was obtained and agreed upon. The Delphi surveys were sent to 37 consortium experts. After round 1 (28 responses), 13 pathways reached an agreement \u226580%. Twelve adjusted pathways were presented in round 2 (27 responses), of which 8 received an agreement \u226580%. The last four pathways were finalized after expert consensus. Hypertension, heart failure, and overweight were ranked as the most important comorbidities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A structured process of expert meetings and two Delphi rounds led to the development and ranking of 23 concise care pathways to identify and manage comorbidities in patients with AF. All pathways will be combined into a software tool, providing clinicians with a systematic approach to comorbidity management, which will be tested in the RCT of EHRA-PATHS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjopen\/oeaf120","type":"journal-article","created":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T11:39:32Z","timestamp":1757763572000},"source":"Crossref","is-referenced-by-count":2,"title":["Development of three-step holistic care pathways to detect and manage comorbidities in patients with atrial fibrillation: the Horizon 2020 EHRA-PATHS consortium"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9305-634X","authenticated-orcid":false,"given":"Rana","family":"\u00d6nder","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Life Sciences, Hasselt University , Martelarenlaan 42, Hasselt 3500 ,","place":["Belgium"]},{"name":"Heart Centre Hasselt, Jessa Hospital , Stadsomvaart 11, Hasselt 3500 ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8641-4658","authenticated-orcid":false,"given":"Lien","family":"Desteghe","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Life Sciences, Hasselt University , Martelarenlaan 42, Hasselt 3500 ,","place":["Belgium"]},{"name":"Heart Centre Hasselt, Jessa Hospital , Stadsomvaart 11, Hasselt 3500 ,","place":["Belgium"]},{"name":"Department of Cardiology, Antwerp University Hospital , Drie Eikenstraat 655, Edegem 2650 ,","place":["Belgium"]},{"name":"Centre for Research and Innovation in Care (CRIC), Department of Nursing and Midwifery Sciences, University of Antwerp , Prinsstraat 13, Antwerp 2000 ,","place":["Belgium"]},{"name":"Research Group Cardiovascular Diseases, GENCOR, University of Antwerp , Prinsstraat 13, Antwerp 2000 ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4928-4836","authenticated-orcid":false,"given":"Johan","family":"Vijgen","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Life Sciences, Hasselt University , Martelarenlaan 42, Hasselt 3500 ,","place":["Belgium"]},{"name":"Heart Centre Hasselt, Jessa Hospital , Stadsomvaart 11, Hasselt 3500 ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0404-8266","authenticated-orcid":false,"given":"R\u00f3n\u00e1n","family":"Collins","sequence":"additional","affiliation":[{"name":"Department of Gerontology Trinity College and Tallaght University Hospital, Tallaght, Dublin D24 NR0A ,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5602-0313","authenticated-orcid":false,"given":"Rafal","family":"Dabrowski","sequence":"additional","affiliation":[{"name":"Department of Coronary Artery Disease and Cardiac Rehabilitation, National Institute of Cardiology , Alpejska 42, Warsaw 04-628 ,","place":["Poland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1673-7712","authenticated-orcid":false,"given":"Michal Miroslaw","family":"Farkowski","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ministry of Interior and Administration National Medical Institute , Woloska 137, Warsaw 02-507 ,","place":["Poland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3477-4667","authenticated-orcid":false,"given":"Marcio Jansen","family":"de Oliveira Figueiredo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Campinas (UNICAMP) Medical School , Campinas, R. Tessalia Vieira de Camargo 126, Sao Paulo 13083-887 ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8896-6293","authenticated-orcid":false,"given":"Maartje J M","family":"Hereijgers","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Respiratory Medicine, Maastricht University Medical Centre + , P. Debyelaan 25, Maastricht 6229 HX ,","place":["the Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8164-6329","authenticated-orcid":false,"given":"Daniel","family":"Hofer","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital Zurich , R\u00e4mistrasse 100, Zurich 8091 ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3526-8950","authenticated-orcid":false,"given":"Chu-Pak","family":"Lau","sequence":"additional","affiliation":[{"name":"The Department of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6385-8600","authenticated-orcid":false,"given":"Geraldine","family":"Lee","sequence":"additional","affiliation":[{"name":"School of Nursing & Midwifery, Brookfield Health Sciences Complex, University College Cork , Cork T12 AK54, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4893-0824","authenticated-orcid":false,"given":"Dominik","family":"Linz","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center , Universiteitssingel 50, Maastricht 6629 ER ,","place":["The Netherlands"]},{"name":"Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen , Blegdamsvej 3B, Copenhagen 2200 ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0531-6741","authenticated-orcid":false,"given":"Michelle","family":"Lobeek","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Groningen, University Medical Center Groningen , Groningen ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3414-7022","authenticated-orcid":false,"given":"Teresa","family":"Lopez","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardio-Oncology Unit, La Paz University Hospital, IdiPAZ Research Institute, Paseo de la Castellena 261, Madrid 28046 ,","place":["Spain"]},{"name":"Cardio-Oncology Unit, Cardiology Department, Quironsalud Madrid , Diego de Velazques, Madrid 28223 ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9398-4339","authenticated-orcid":false,"given":"Christine","family":"McAuliffe","sequence":"additional","affiliation":[{"name":"Pharmacy Department, Tallaght University Hospital , Tallaght, Dublin D24 NR0A ,","place":["Ireland"]},{"name":"School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences , St Stephen's Green 111, Dublin D02 VN51 ,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1737-1903","authenticated-orcid":false,"given":"Jose Luis","family":"Merino","sequence":"additional","affiliation":[{"name":"Department of Cardiology, La Paz University Hospital , Paseo de la Castellena 261, Madrid 28046 ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6285-6902","authenticated-orcid":false,"given":"Tatjana","family":"Potpara","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Belgrade University , Dr. Subotica-starijeg 8, Belgrade 11000 ,","place":["Serbia"]},{"name":"Cardiology Clinic, University Clinical Centre of Serbia , Pasterova 2, Belgrade 11000 ,","place":["Serbia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3803-8429","authenticated-orcid":false,"given":"Prashanthan","family":"Sanders","sequence":"additional","affiliation":[{"name":"Centre for Heart Rhythm Disorders, University of Adelaide and Royal Adelaide Hospital , Adelaide ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4894-8664","authenticated-orcid":false,"given":"Alireza Sepehri","family":"Shamloo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Deutsches Herzzentrum der Charit\u00e9-Medical Heart Center of Charit\u00e9, German Heart Institute Berlin , Augustenburger Platz 1, Berlin 13353 ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maciej","family":"Sterli\u0144ski","sequence":"additional","affiliation":[{"name":"1st Arrhythmia Department, National Institute of Cardiology , Alpejska 42, Warszawa 04-628 ,","place":["Poland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6413-0870","authenticated-orcid":false,"given":"Emma","family":"Svennberg","sequence":"additional","affiliation":[{"name":"Karolinska Institutet, Department of Medicine (MedH), Karolinska University Hospital Huddinge , Stockholm ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5116-7378","authenticated-orcid":false,"given":"Colinda","family":"van Deutekom","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Groningen, University Medical Center Groningen , Groningen ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7579-1201","authenticated-orcid":false,"given":"Isabelle","family":"Van Gelder","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Groningen, University Medical Center Groningen , Groningen ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2581-070X","authenticated-orcid":false,"given":"Michiel","family":"Rienstra","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Groningen, University Medical Center Groningen , Groningen ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9301-8127","authenticated-orcid":false,"given":"Hein","family":"Heidbuchel","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Life Sciences, Hasselt University , Martelarenlaan 42, Hasselt 3500 ,","place":["Belgium"]},{"name":"Department of Cardiology, Antwerp University Hospital , Drie Eikenstraat 655, Edegem 2650 ,","place":["Belgium"]},{"name":"Research Group Cardiovascular Diseases, GENCOR, University of Antwerp , Prinsstraat 13, Antwerp 2000 ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,10,27]]},"reference":[{"key":"2025102704015806900_oeaf120-B1","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/s11886-018-0975-x","article-title":"Addressing multimorbidity and polypharmacy in individuals with atrial fibrillation","volume":"20","author":"Shaikh","year":"2018","journal-title":"Curr Cardiol Rep"},{"key":"2025102704015806900_oeaf120-B2","doi-asserted-by":"crossref","first-page":"e002641","DOI":"10.1136\/openhrt-2024-002641","article-title":"Multimorbidity in patients with atrial fibrillation","volume":"11","author":"Lobeek","year":"2024","journal-title":"Open Heart"},{"key":"2025102704015806900_oeaf120-B3","doi-asserted-by":"crossref","first-page":"f329","DOI":"10.1093\/europace\/eux322","article-title":"Multimorbidity and co-morbidity in atrial fibrillation and effects on survival: findings from UK biobank cohort","volume":"20","author":"Jani","year":"2018","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B4","doi-asserted-by":"crossref","first-page":"ehae666-514","DOI":"10.1093\/eurheartj\/ehae666.514","article-title":"Abstract: cluster-specific predictors of early rhythm control in contemporary European cohort of patients with atrial fibrillation: the EHRA-PATHS project","volume":"45","author":"Potpara","year":"2024","journal-title":"Eur Heart J"},{"key":"2025102704015806900_oeaf120-B5","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1093\/europace\/euy137","article-title":"Integrated care to reduce atrial fibrillation burden: do not underrate the overweight!","volume":"20","author":"Smit","year":"2018","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B6","doi-asserted-by":"crossref","first-page":"euae021","DOI":"10.1093\/europace\/euae021","article-title":"Impact of chronic obstructive pulmonary disease in patients with atrial fibrillation: an analysis from the GLORIA-AF registry","volume":"26","author":"Romiti","year":"2023","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B7","doi-asserted-by":"crossref","first-page":"euae173","DOI":"10.1093\/europace\/euae173","article-title":"Atrial fibrillation accelerates functional decline in older adults: a 15-year follow-up population-based study","volume":"26","author":"Okoye","year":"2024","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B8","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1093\/europace\/euaa340","article-title":"Effect of alcohol consumption on the risk of adverse events in atrial fibrillation: from the COmparison study of Drugs for symptom control and complication prEvention of Atrial Fibrillation (CODE-AF) registry","volume":"23","author":"Lim","year":"2021","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B9","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1093\/europace\/euaa275","article-title":"Sleep apnoea has a dose-dependent effect on atrial remodelling in paroxysmal but not persistent atrial fibrillation: a high-density mapping study","volume":"23","author":"Nalliah","year":"2021","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B10","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1093\/europace\/euz358","article-title":"Management of atrial fibrillation in patients with chronic kidney disease in clinical practice: a joint European Heart Rhythm Association (EHRA) and European Renal Association\/European Dialysis and Transplantation Association (ERA\/EDTA) physician-based survey","volume":"22","author":"Potpara","year":"2020","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B11","doi-asserted-by":"crossref","first-page":"e0296413","DOI":"10.1371\/journal.pone.0296413","article-title":"Subclinical thyroid dysfunction and the risk of incident atrial fibrillation: a systematic review and meta-analysis","volume":"19","author":"Singh","year":"2024","journal-title":"PLoS One"},{"key":"2025102704015806900_oeaf120-B12","doi-asserted-by":"crossref","first-page":"100784","DOI":"10.1016\/j.lanepe.2023.100784","article-title":"Atrial fibrillation: comorbidities, lifestyle, and patient factors","volume":"37","author":"Shantsila","year":"2024","journal-title":"Lancet Reg Health Eur"},{"key":"2025102704015806900_oeaf120-B13","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1093\/europace\/euaa274","article-title":"Relation of outcomes to ABC (Atrial Fibrillation Better Care) pathway adherent care in European patients with atrial fibrillation: an analysis from the ESC-EHRA EORP Atrial Fibrillation General Long-Term (AFGen LT) registry","volume":"23","author":"Proietti","year":"2021","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B14","doi-asserted-by":"crossref","first-page":"euae237","DOI":"10.1093\/europace\/euae237","article-title":"Components of the Atrial fibrillation Better Care pathway for holistic care of patients with atrial fibrillation: a win ratio analysis from the COOL-AF registry","volume":"26","author":"Krittayaphong","year":"2024","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B15","doi-asserted-by":"crossref","first-page":"3314","DOI":"10.1093\/eurheartj\/ehae176","article-title":"2024 ESC guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"45","author":"Van Gelder","year":"2024","journal-title":"Eur Heart J"},{"key":"2025102704015806900_oeaf120-B16","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1093\/europace\/euaa210","article-title":"Self-reported treatment burden in patients with atrial fibrillation: quantification, major determinants, and implications for integrated holistic management of the arrhythmia","volume":"22","author":"Potpara","year":"2020","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B17","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1093\/europace\/euac136","article-title":"The challenge of managing multimorbid atrial fibrillation: a pan-European European Heart Rhythm Association (EHRA) member survey of current management practices and clinical priorities","volume":"24","author":"Lee","year":"2022","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B18","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1093\/eurheartj\/ehab672","article-title":"ESC and EHRA lead a path towards integrated care for multimorbid atrial fibrillation patients: the Horizon 2020 EHRA-PATHS project","volume":"43","author":"Heidbuchel","year":"2022","journal-title":"Eur Heart J"},{"key":"2025102704015806900_oeaf120-B19","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/eurheartj\/ehaa612","article-title":"2020 ESC guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): the task force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC","volume":"42","author":"Hindricks","year":"2021","journal-title":"Eur Heart J"},{"key":"2025102704015806900_oeaf120-B20","doi-asserted-by":"crossref","first-page":"3227","DOI":"10.1093\/eurheartj\/ehab484","article-title":"2021 ESC guidelines on cardiovascular disease prevention in clinical practice","volume":"42","author":"Visseren","year":"2021","journal-title":"Eur Heart J"},{"key":"2025102704015806900_oeaf120-B21","doi-asserted-by":"crossref","first-page":"ehae666514","DOI":"10.1093\/eurheartj\/ehae666.514","article-title":"Cluster-specific predictors of early rhythm control in contemporary European cohort of patients with atrial fibrillation: the EHRA-PATHS project","volume":"45:","author":"Potpara","year":"2024","journal-title":"Eur Heart J"},{"key":"2025102704015806900_oeaf120-B22","doi-asserted-by":"crossref","first-page":"ehae666515","DOI":"10.1093\/eurheartj\/ehae666.515","article-title":"Cluster-specific risk factors for suboptimal thromboprophylaxis in contemporary European cohort of patients with atrial fibrillation: the EHRA-PATHS project","volume":"45","author":"Mihajlovic","year":"2024","journal-title":"Eur Heart J"},{"key":"2025102704015806900_oeaf120-B23","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1093\/ehjqcco\/qcaa050","article-title":"Cohort profile: the ESC EURObservational Research Programme Atrial Fibrillation III (AF III) registry","volume":"7","author":"Potpara","year":"2021","journal-title":"Eur Heart J Qual Care Clin Outcomes"},{"key":"2025102704015806900_oeaf120-B24","doi-asserted-by":"crossref","DOI":"10.1093\/europace\/euaf111","article-title":"Implementation of new concise care pathways into a software tool to detect and manage comorbidities in older patients with atrial fibrillation: the Horizon 2020 EHRA-PATHS project","author":"\u00d6nder","year":"2025","journal-title":"EP Europace"},{"key":"2025102704015806900_oeaf120-B25"},{"key":"2025102704015806900_oeaf120-B26","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.1093\/eurheartj\/ehs071","article-title":"Nurse-led care vs. usual care for patients with atrial fibrillation: results of a randomized trial of integrated chronic care vs. routine clinical care in ambulatory patients with atrial fibrillation","volume":"33","author":"Hendriks","year":"2012","journal-title":"Eur Heart J"},{"key":"2025102704015806900_oeaf120-B27","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/S0140-6736(14)61992-9","article-title":"Standard versus atrial fibrillation-specific management strategy (SAFETY) to reduce recurrent admission and prolong survival: pragmatic, multicentre, randomised controlled trial","volume":"385","author":"Stewart","year":"2015","journal-title":"Lancet"},{"key":"2025102704015806900_oeaf120-B28","doi-asserted-by":"crossref","first-page":"e002950","DOI":"10.1161\/JAHA.115.002950","article-title":"An integrated management approach to atrial fibrillation","volume":"5","author":"Carter","year":"2016","journal-title":"J Am Heart Assoc"},{"key":"2025102704015806900_oeaf120-B29","doi-asserted-by":"crossref","first-page":"e32625","DOI":"10.2196\/32625","article-title":"Adherence to a multidisciplinary lifestyle program for patients with atrial fibrillation and obesity: feasibility study","volume":"6","author":"Tenbult","year":"2022","journal-title":"JMIR Form Res"},{"key":"2025102704015806900_oeaf120-B30","doi-asserted-by":"crossref","first-page":"e024319","DOI":"10.1161\/JAHA.121.024319","article-title":"Effects of the atrial fibrillation better care pathway on outcomes among clinically complex Chinese patients with atrial fibrillation with multimorbidity and polypharmacy: a report from the ChiOTEAF registry","volume":"11","author":"Kotalczyk","year":"2022","journal-title":"J Am Heart Assoc"},{"key":"2025102704015806900_oeaf120-B31","doi-asserted-by":"crossref","first-page":"856222","DOI":"10.3389\/fcvm.2022.856222","article-title":"Impact of integrated care management on clinical outcomes in atrial fibrillation patients: a report from the FANTASIIA registry","volume":"9","author":"Esteve-Pastor","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"2025102704015806900_oeaf120-B32","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s11606-022-07567-5","article-title":"The Atrial Fibrillation Better Care (ABC) pathway and clinical outcomes in patients with atrial fibrillation: the prospective Murcia AF project phase II cohort","volume":"38","author":"Rivera-Caravaca","year":"2023","journal-title":"J Gen Intern Med"},{"key":"2025102704015806900_oeaf120-B33","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1093\/europace\/euac082","article-title":"Evaluation of the atrial fibrillation better care pathway in the ENGAGE AF-TIMI 48 trial","volume":"24","author":"Patel","year":"2022","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B34","doi-asserted-by":"crossref","first-page":"101757","DOI":"10.1016\/j.eclinm.2022.101757","article-title":"Adherence to the Atrial Fibrillation Better Care (ABC) pathway and the risk of major outcomes in patients with atrial fibrillation: a post-hoc analysis from the prospective GLORIA-AF registry","volume":"55","author":"Romiti","year":"2023","journal-title":"EClinicalMedicine"},{"key":"2025102704015806900_oeaf120-B35","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.jacasi.2022.01.007","article-title":"Atrial fibrillation better care pathway adherent care improves outcomes in Chinese patients with atrial fibrillation","volume":"2","author":"Guo","year":"2022","journal-title":"JACC Asia"},{"key":"2025102704015806900_oeaf120-B36","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.ejim.2022.11.004","article-title":"Impact of ABC (Atrial Fibrillation Better Care) pathway adherence in high-risk subgroups with atrial fibrillation: a report from the ESC-EHRA EORP-AF long-term general registry","volume":"107","author":"Ding","year":"2023","journal-title":"Eur J Intern Med"},{"key":"2025102704015806900_oeaf120-B37","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1093\/eurheartj\/ehz666","article-title":"Nurse-led vs. usual-care for atrial fibrillation","volume":"41","author":"Wijtvliet","year":"2020","journal-title":"Eur Heart J"},{"key":"2025102704015806900_oeaf120-B38","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1016\/j.jacc.2014.09.028","article-title":"Aggressive risk factor reduction study for atrial fibrillation and implications for the outcome of ablation: the ARREST-AF cohort study","volume":"64","author":"Pathak","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"2025102704015806900_oeaf120-B39","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1016\/j.jacc.2015.03.002","article-title":"Long-term effect of goal-directed weight management in an atrial fibrillation cohort: a long-term follow-up study (LEGACY)","volume":"65","author":"Pathak","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"2025102704015806900_oeaf120-B40","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1093\/europace\/euy117","article-title":"PREVEntion and regReSsive Effect of weight-loss and risk factor modification on Atrial Fibrillation: the REVERSE-AF study","volume":"20","author":"Middeldorp","year":"2018","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B41","doi-asserted-by":"crossref","first-page":"2050","DOI":"10.1001\/jama.2013.280521","article-title":"Effect of weight reduction and cardiometabolic risk factor management on symptom burden and severity in patients with atrial fibrillation: a randomized clinical trial","volume":"310","author":"Abed","year":"2013","journal-title":"JAMA"},{"key":"2025102704015806900_oeaf120-B42","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1056\/NEJMoa1817591","article-title":"Alcohol abstinence in drinkers with atrial fibrillation","volume":"382","author":"Voskoboinik","year":"2020","journal-title":"N Engl J Med"},{"key":"2025102704015806900_oeaf120-B43","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.3390\/jcm10112238","article-title":"Smoking cessation after diagnosis of new-onset atrial fibrillation and the risk of stroke and death","volume":"10","author":"Lee","year":"2021","journal-title":"J Clin Med"},{"key":"2025102704015806900_oeaf120-B44","doi-asserted-by":"crossref","first-page":"euae178","DOI":"10.1093\/europace\/euae178","article-title":"Design and deployment of the STEEER-AF trial to evaluate and improve guideline adherence: a cluster-randomized trial by the European Society of Cardiology and European Heart Rhythm Association","volume":"26","author":"Sterlinski","year":"2024","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B45","doi-asserted-by":"crossref","first-page":"e007411","DOI":"10.1161\/CIRCOUTCOMES.120.007411","article-title":"Integrated care in atrial fibrillation: a road map to the future","volume":"14","author":"Bhat","year":"2021","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"2025102704015806900_oeaf120-B46","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1093\/europace\/euab092","article-title":"The Atrial Fibrillation Better Care pathway for managing atrial fibrillation: a review","volume":"23","author":"Stevens","year":"2021","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B47","doi-asserted-by":"crossref","first-page":"euae211","DOI":"10.1093\/europace\/euae211","article-title":"Effect of targeted education of patients with atrial fibrillation on unplanned cardiovascular outcomes: results of the multicentre randomized AF-EduCare trial","volume":"27","author":"Desteghe","year":"2024","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B48","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1093\/europace\/euz209","article-title":"Integrated specialized atrial fibrillation clinics reduce all-cause mortality: post hoc analysis of a randomized clinical trial","volume":"21","author":"Hendriks","year":"2019","journal-title":"Europace"},{"key":"2025102704015806900_oeaf120-B49"},{"key":"2025102704015806900_oeaf120-B50"}],"container-title":["European Heart Journal Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjopen\/article-pdf\/5\/5\/oeaf120\/64927014\/oeaf120.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjopen\/article-pdf\/5\/5\/oeaf120\/64927014\/oeaf120.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T08:02:08Z","timestamp":1761552128000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjopen\/article\/doi\/10.1093\/ehjopen\/oeaf120\/8301115"}},"subtitle":[],"editor":[{"given":"Christian","family":"de Chillou","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,8,29]]},"references-count":50,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,8,29]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjopen\/oeaf120","relation":{},"ISSN":["2752-4191"],"issn-type":[{"type":"electronic","value":"2752-4191"}],"subject":[],"published-other":{"date-parts":[[2025,9]]},"published":{"date-parts":[[2025,8,29]]},"article-number":"oeaf120"}}