{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T02:30:45Z","timestamp":1791599445042,"version":"4.3.4"},"reference-count":51,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T00:00:00Z","timestamp":1634083200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000056","name":"National Institute of Nursing Research","doi-asserted-by":"publisher","award":["R00NR016275"],"award-info":[{"award-number":["R00NR016275"]}],"id":[{"id":"10.13039\/100000056","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01HL152021"],"award-info":[{"award-number":["R01HL152021"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01HL152021"],"award-info":[{"award-number":["R01HL152021"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>We conducted a systematic review and meta-analysis to evaluate temporal trends in quality of life (QoL) after coronary artery bypass grafting (CABG) surgery in randomized clinical trials, and a quantitative comparison from before surgery to up to 5\u00a0years after surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>We searched MEDLINE, CINAHL, EMBASE, Cochrane Library, and PsycINFO from 2010 to 2020 to identify studies that included the measurement of QoL in patients undergoing CABG. The primary outcome was the Seattle Angina Questionnaire (SAQ), and secondary outcomes were the 36-item Short Form Health Survey (SF-36) and EuroQol Questionnaire (EQ-5D). We pooled the means and the weighted mean differences over the follow-up period. In the meta-analysis, 2586 studies were screened and 18 full-text studies were included. There was a significant trend towards higher QoL scores from before surgery to 1\u00a0year post-operatively for the SAQ angina frequency (AF), SAQ QoL, SF-36 physical component (PC), and EQ-5D, whereas the SF-36 mental component (MC) did not improve significantly. The weighted mean differences from before surgery to 1\u00a0year after was 24 [95% confidence interval (CI): 21.6\u201326.4] for the SAQ AF, 31 (95% CI: 27.5\u201334.6) for the SAQ QoL, 9.8 (95% CI: 7.1\u201312.8) for the SF-36 PC, 7.1 (95% CI: 4.2\u201310.0) for the SF-36 MC, and 0.1 (95% CI: 0.06\u20130.14) for the EQ-5D. There was no evidence of publication bias or small-study effect.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>CABG had both short- and long-term improvements in disease-specific QoL and generic QoL, with the largest improvement in angina frequency.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjqcco\/qcab075","type":"journal-article","created":{"date-parts":[[2021,10,8]],"date-time":"2021-10-08T11:11:13Z","timestamp":1633691473000},"page":"259-268","source":"Crossref","is-referenced-by-count":41,"title":["Effect of coronary artery bypass grafting on quality of life: a meta-analysis of randomized trials"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4238-9902","authenticated-orcid":false,"given":"Ruth Masterson","family":"Creber","sequence":"first","affiliation":[{"name":"Division of Health Informatics, Department of Healthcare Policy and Research, Weill Cornell Medicine , New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0055-8656","authenticated-orcid":false,"given":"Arnaldo","family":"Dimagli","sequence":"additional","affiliation":[{"name":"Bristol Heart Institute, University of Bristol , Bristol, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristiano","family":"Spadaccio","sequence":"additional","affiliation":[{"name":"Institute of Cardiovascular and Medical Sciences, University of Glasgow , UK"},{"name":"Lancashire Cardiac Center, Blackpool Victoria Teaching Hospital , Blackpool, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie","family":"Myers","sequence":"additional","affiliation":[{"name":"Division of Health Informatics, Department of Healthcare Policy and Research, Weill Cornell Medicine , New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8373-8486","authenticated-orcid":false,"given":"Marco","family":"Moscarelli","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Imperial College London , London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4997-7707","authenticated-orcid":false,"given":"Michelle","family":"Demetres","sequence":"additional","affiliation":[{"name":"Samuel J. 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