{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T14:50:44Z","timestamp":1783435844911,"version":"3.54.6"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T00:00:00Z","timestamp":1641254400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100001030","name":"National Heart Foundation of Australia","doi-asserted-by":"publisher","award":["101186"],"award-info":[{"award-number":["101186"]}],"id":[{"id":"10.13039\/501100001030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Recent US studies report rising rates of mortality and in-hospital complications following catheter ablation of atrial fibrillation (AF), but whether this is a global phenomenon is uncertain. The aim of this study was to examine trends in 30-day mortality and complications following AF ablation in Australia and New Zealand (ANZ) from 2008 to 2017.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>We identified 37\u00a0243 AF (mean age 62.4 \u00b1 11.5\u00a0years, 29.6% females, 94.5% elective procedures) ablations using national hospitalization data. The primary outcome was occurrence of any complication, including all-cause mortality, within 30\u00a0days of discharge. Trends were evaluated using logistic regression adjusting for changes in patient characteristics. The annual number of ablations increased from 1359 (2008) to 5115 (2017). Patients\u2019 age and rates of heart failure (9.8\u201310.6%), diabetes (6.8\u201312.4%), and chronic kidney disease (2.2\u20134.1%) also increased over time. From 2008 to 2017, the overall rate of complications declined from 7.51% to 5.04% [adjusted odds ratio (aOR) 0.96 (95% confidence interval, CI, 0.94\u20130.97)\/year]. Rates of pericardial effusion [1.69\u20130.70%, aOR 0.93 (0.89\u20130.97)], bleeding [4.49\u20132.74%, aOR 0.94 (0.92\u20130.96)], and vascular injury [0.52\u20130.16%, aOR 0.91 (0.85\u20130.98)] declined, but rates of acute kidney injury [0.15\u20130.68%, aOR 1.16 (1.08\u20131.25)] and infection [0.15\u20130.57%, aOR 1.07 (1.01\u20131.14)] increased over time. The overall 30-day mortality rate was low (0.11%) and unchanged [0.00\u20130.16%, aOR 0.99 (0.88\u20131.11)].<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Despite a five-fold increase in AF ablations and the rising risk profile of patients, complications following AF ablation declined by 30% from 2008 to 2017 in ANZ. Procedure-related death was uncommon and occurred in less than 1 in 850 patients.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjqcco\/qcab102","type":"journal-article","created":{"date-parts":[[2022,1,2]],"date-time":"2022-01-02T12:05:59Z","timestamp":1641125159000},"page":"398-408","source":"Crossref","is-referenced-by-count":36,"title":["Ten-year trends in mortality and complications following catheter ablation of atrial fibrillation"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4058-0412","authenticated-orcid":false,"given":"Linh","family":"Ngo","sequence":"first","affiliation":[{"name":"School of Clinical Medicine, Faculty of Medicine, the University of Queensland , QLD, Brisbane, Australia"},{"name":"Department of Cardiology, The Prince Charles Hospital , 627 Rode Road, Chermside, QLD 4032, Brisbane, Australia"},{"name":"Department of Cardiovascular and Thoracic Surgery, Cardiovascular Centre, E Hospital , Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Ali","sequence":"additional","affiliation":[{"name":"School of Medicine, Faculty of Health and Medical Sciences, the University of Adelaide , SA, Adelaide, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anand","family":"Ganesan","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Flinders Medical Centre , SA, Australia"},{"name":"College of Medicine and Public Health, Flinders University , SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Woodman","sequence":"additional","affiliation":[{"name":"Flinders Centre for Epidemiology and Biostatistics, College of Medicine and Public Health, Flinders University , SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Adams","sequence":"additional","affiliation":[{"name":"College of Medicine and Public Health, Flinders University , SA, Australia"},{"name":"Respiratory and Sleep Services, Southern Adelaide Local Health Network , SA, Adelaide, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isuru","family":"Ranasinghe","sequence":"additional","affiliation":[{"name":"School of Clinical Medicine, Faculty of Medicine, the University of Queensland , QLD, Brisbane, Australia"},{"name":"Department of Cardiology, The Prince Charles Hospital , 627 Rode Road, Chermside, QLD 4032, Brisbane, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,1,4]]},"reference":[{"key":"2022060701391820200_bib1","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1001\/jama.2019.0693","article-title":"Effect of catheter ablation vs. antiarrhythmic drug therapy on mortality, stroke, bleeding, and cardiac arrest among patients with atrial fibrillation: the CABANA randomized clinical 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