{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T13:42:30Z","timestamp":1767706950760,"version":"3.37.3"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T00:00:00Z","timestamp":1664323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001003","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001003","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004326","name":"Bayer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004326","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016674","name":"Novo","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100016674","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>Describe and compare incidences across age groups of rehospitalization, repeated aortic surgery, and death in patients who survived surgery and hospitalization for type A aortic dissection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>From Danish nationwide registries, we identified patients hospitalized with Stanford type A aortic dissections (2006\u20132018). Survivors of hospitalization and surgery on the ascending aorta and\/or aortic arch comprised the study population (n\u00a0=\u00a0606, 36 (38.9%) &amp;lt;60 years old (group I), 194 (32.0%) 60\u201369 years old (group II), and 176 (29.1%) &amp;gt;69 years old (group III)). During the first year, 62.5% were re-hospitalized and 1.4% underwent repeated aortic surgery with no significant differences across age groups (P\u00a0=\u00a00.68 and P\u00a0=\u00a00.39, respectively). Further, 5.9% died (group I: 3.0%, group II: 8.3%, group III: 7.4%, P\u00a0=\u00a00.04). After 10 years, 8.0% had undergone repeated aortic surgery (group I: 11.5%, group II: 8.5%, group III: 1.6%, P\u00a0=\u00a00.04) and 10.2% (group I), 17.0% (group II), and 22.2% (group III) had died (P\u00a0=\u00a00.01). Using multivariable Cox regression analysis, we described long-term outcomes comparing age groups. No age differences were found in one-year outcomes, while age\u00a0&amp;gt;\u00a069 years compared with age\u00a0&amp;lt;\u00a060 years was associated with a lower rate of repeated aortic surgery [hazard ratio 0.17, 95% confidence interval (CI) 0.04\u20130.78] and a higher rate of all-cause mortality (hazard ratio 2.44, 95% CI 1.37\u20134.34) in the 10-year analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Rehospitalisations in the first year after discharge were common in all age groups, but survival was high. Repeated aortic surgery was significantly more common among younger than older patients.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ehjqcco\/qcac061","type":"journal-article","created":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T23:18:53Z","timestamp":1664407133000},"page":"520-528","source":"Crossref","is-referenced-by-count":2,"title":["Rehospitalisations, repeated aortic surgery, and death in initial survivors of surgery for Stanford type A aortic dissection and the significance of age - a nationwide registry-based cohort study"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3307-5944","authenticated-orcid":false,"given":"Anna","family":"Gundlund","sequence":"first","affiliation":[{"name":"Department of Cardiology, Copenhagen University Hospital, Rigshospitalet , Blegdamsvej 3, 2100 Copenhagen , Denmark"},{"name":"Department of Cardiology, Copenhagen University Hospital, Herlev and Gentofte Hospital, Hospitalsvej 1 , 2820 Gentofte , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6635-1466","authenticated-orcid":false,"given":"Lars","family":"K\u00f8ber","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Copenhagen University Hospital, Rigshospitalet , Blegdamsvej 3, 2100 Copenhagen , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan E","family":"H\u00f8fsten","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Copenhagen University Hospital, Rigshospitalet , Blegdamsvej 3, 2100 Copenhagen , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morten","family":"Vester-Andersen","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Copenhagen University Hospital, Herlev and Gentofte Hospital, Herlev, Borgmester Ibs Juuls vej 1, 2730 Herlev , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria W","family":"Pedersen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Aalborg University Hospital , Hobrovej 18-22, 9000 Aalborg , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2892-6131","authenticated-orcid":false,"given":"Christian","family":"Torp-Pedersen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Nordsj\u00e6llands Hospital , 3400 Hiller\u00f8d , Denmark"},{"name":"Department of Cardiology, Aalborg University Hospital , Hobrovej 18-22, 9000 Aalborg , Denmark"},{"name":"Department of Public Health, University of Copenhagen , 1165, Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristian","family":"Kragholm","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Aalborg University Hospital , Hobrovej 18-22, 9000 Aalborg , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"S\u00f8gaard","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Aalborg University Hospital , Hobrovej 18-22, 9000 Aalborg , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8482-030X","authenticated-orcid":false,"given":"Morten","family":"Smerup","sequence":"additional","affiliation":[{"name":"Department of thoracic surgery, Copenhagen University Hospital, Rigshospitalet , Blegdamsvej 3, 2100 Copenhagen , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emil L","family":"Fosb\u00f8l","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Copenhagen University Hospital, Rigshospitalet , Blegdamsvej 3, 2100 Copenhagen , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,9,28]]},"reference":[{"key":"2023080708281232100_bib1","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.jacc.2015.05.029","article-title":"Presentation, diagnosis, and outcomes of acute aortic dissection: 17-year trends from the International Registry of Acute Aortic Dissection","volume":"66","author":"Pape","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"2023080708281232100_bib2","doi-asserted-by":"crossref","first-page":"2873","DOI":"10.1093\/eurheartj\/ehu281","article-title":"2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. 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