{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T17:25:02Z","timestamp":1793381102166,"version":"4.5.0"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,12,15]],"date-time":"2024-12-15T00:00:00Z","timestamp":1734220800000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"publisher","award":["101136962"],"award-info":[{"award-number":["101136962"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"publisher","award":["2\u2014M4C2"],"award-info":[{"award-number":["2\u2014M4C2"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"publisher","award":["3277"],"award-info":[{"award-number":["3277"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Italian Ministry of University and Research","award":["ECS00000041"],"award-info":[{"award-number":["ECS00000041"]}]},{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Myocarditis UK"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Dilated cardiomyopathy (DCM) is extensively discussed in numerous expert consensus documents and international guidelines, with differing recommendations. To support clinicians in daily practice and decision-making, we conducted a systematic review of key guidelines and recommendations concerning the diagnosis and clinical management of DCM. Our research encompassed MEDLINE and EMBASE databases for relevant articles published, as well as the websites of relevant scientific societies. We identified two guidelines and one scientific statement that met stringent criteria, thereby qualifying them for detailed systematic analysis. Our review revealed consensus on several key aspects: the definition of DCM, the use of B-type natriuretic peptides and high-sensitivity troponin in laboratory testing, the essential role of multimodality cardiovascular imaging for initial diagnosis, genetic counselling, and the management of advanced disease. Nonetheless, notable areas of variation included the formation of multidisciplinary management teams, the role of cascade genetic testing, pathways for arrhythmic risk stratification, and the criteria for prophylactic defibrillator implantation. Significant evidence gaps persist, particularly regarding the clinical trajectory of genetic, non-genetic and gene-elusive forms of DCM, the use of cardiovascular magnetic resonance in phenotype-negative family members with genotype-positive probands, and the development of potential aetiology-oriented therapies. Addressing these gaps could enhance clinical outcomes and inform future research directions and guideline development.<\/jats:p>","DOI":"10.1093\/ehjqcco\/qcae109","type":"journal-article","created":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T07:28:34Z","timestamp":1734074914000},"page":"206-222","source":"Crossref","is-referenced-by-count":32,"title":["Diagnosis and management of dilated cardiomyopathy: a systematic review of clinical practice guidelines and recommendations"],"prefix":"10.1093","volume":"11","author":[{"given":"Anna","family":"Sorella","sequence":"first","affiliation":[{"name":"Department of Neuroscience, Imaging and Clinical Sciences, G. D'Annunzio University of Chieti-Pescara , 66100 Chieti ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9207-8985","authenticated-orcid":false,"given":"Kristian","family":"Galanti","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Imaging and Clinical Sciences, G. D'Annunzio University of Chieti-Pescara , 66100 Chieti ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorena","family":"Iezzi","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Imaging and Clinical Sciences, G. D'Annunzio University of Chieti-Pescara , 66100 Chieti ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabina","family":"Gallina","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Imaging and Clinical Sciences, G. D'Annunzio University of Chieti-Pescara , 66100 Chieti ,","place":["Italy"]},{"name":"University Cardiology Division, Heart Department, SS. Annunziata Polyclinic , Chieti 66100 ,","place":["Italy"]},{"name":"Institute for Advanced Biomedical Technologies, G. D'Annunzio University of Chieti-Pescara , 66100 Chieti ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selma F","family":"Mohammed","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Creighton University School of Medicine , Omaha, NE 68124 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Sekhri","sequence":"additional","affiliation":[{"name":"Barts Heart Centre, St. Bartholomew's Hospital, Barts Health NHS Trust , West Smithfield, London EC1A 7BE ,","place":["UK"]},{"name":"Newham University Hospital, Barts Health NHS Trust , London EC1M 6BQ ,","place":["UK"]},{"name":"William Harvey Research Institute, NIHR Barts Biomedical Centre, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Majid","family":"Akhtar","sequence":"additional","affiliation":[{"name":"Royal Brompton and Harefield Hospitals , Guy's and St Thomas\u2019 NHS Foundation Trust, London SW3 6NP ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay K","family":"Prasad","sequence":"additional","affiliation":[{"name":"Royal Brompton and Harefield Hospitals , Guy's and St Thomas\u2019 NHS Foundation Trust, London SW3 6NP ,","place":["UK"]},{"name":"National Heart and Lung Institute, Imperial College London , London SW7 2AZ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Choudhary Anwar Ahmed","family":"Chahal","sequence":"additional","affiliation":[{"name":"Barts Heart Centre, St. Bartholomew's Hospital, Barts Health NHS Trust , West Smithfield, London EC1A 7BE ,","place":["UK"]},{"name":"William Harvey Research Institute, NIHR Barts Biomedical Centre, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]},{"name":"Center for Inherited Cardiovascular Diseases, Department of Cardiology , WellSpan Health, 30 Monument Rd, York , PA 17403 ,","place":["USA"]},{"name":"Department of Cardiovascular Medicine, Mayo Clinic , 200 First Str, SW Rochester, MN 55905 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1401-6623","authenticated-orcid":false,"given":"Fabrizio","family":"Ricci","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Imaging and Clinical Sciences, G. D'Annunzio University of Chieti-Pescara , 66100 Chieti ,","place":["Italy"]},{"name":"University Cardiology Division, Heart Department, SS. Annunziata Polyclinic , Chieti 66100 ,","place":["Italy"]},{"name":"Institute for Advanced Biomedical Technologies, G. D'Annunzio University of Chieti-Pescara , 66100 Chieti ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5903-4454","authenticated-orcid":false,"given":"Mohammed Yunus","family":"Khanji","sequence":"additional","affiliation":[{"name":"Barts Heart Centre, St. Bartholomew's Hospital, Barts Health NHS Trust , West Smithfield, London EC1A 7BE ,","place":["UK"]},{"name":"Newham University Hospital, Barts Health NHS Trust , London EC1M 6BQ ,","place":["UK"]},{"name":"William Harvey Research Institute, NIHR Barts Biomedical Centre, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,12,14]]},"reference":[{"key":"2025030423572552400_bib1","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1093\/eurheartj\/ehad194","article-title":"2023 ESC guidelines for the management of cardiomyopathies","volume":"44","author":"Arbelo","year":"2023","journal-title":"Eur Heart J"},{"key":"2025030423572552400_bib2","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1093\/oxfordjournals.eurheartj.a015092","article-title":"Epidemiology of dilated cardiomyopathy. 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