{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:12:03Z","timestamp":1788394323036,"version":"build-2803163510"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T00:00:00Z","timestamp":1735862400000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","award":["FS\/CRTF\/22\/24353"],"award-info":[{"award-number":["FS\/CRTF\/22\/24353"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/X020924\/1"],"award-info":[{"award-number":["MR\/X020924\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Institute for Health and Care Research Barts Biomedical Research Centre","award":["NIHR203330"],"award-info":[{"award-number":["NIHR203330"]}]},{"DOI":"10.13039\/501100015092","name":"St George's University Hospitals NHS Foundation Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015092","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004337","name":"St George's University of London","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004337","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Italian Ministry of University and Research","award":["ECS00000041"],"award-info":[{"award-number":["ECS00000041"]}]},{"DOI":"10.13039\/501100002446","name":"CUP","doi-asserted-by":"publisher","award":["D73C22000840006"],"award-info":[{"award-number":["D73C22000840006"]}],"id":[{"id":"10.13039\/501100002446","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>In light of recent advances in imaging techniques, molecular understanding and therapeutic options in hypertrophic cardiomyopathy (HCM), we performed a systematic review of current guidelines for the diagnosis and management of HCM in order to identify consensus and discrepant areas in the clinical practice guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>We systematically reviewed the English language guidelines and recommendations for the management of HCM in adults. MEDLINE and EMBASE databases were searched for guidelines published in the last 10 years. Following a systematic search, three guidelines on the diagnosis and management of HCM were identified, all of which were robustly developed (AGREE rigour of development score \u226550%). These guidelines were authored by the major European (European Society of Cardiology; 2023), American (American Heart Association \/American College of Cardiology\/American Medical Society for Sports Medicine \/Heart Rhythm Society\/Pediatric and Congenital Electrophysiology Society\/Society for Cardiovascular Magnetic Resonance; 2024), and Japanese [Japanese Circulation Society (JCS)\/Japanese Heart Failure Society (JHFS); 2018] cardiovascular societies. There was broad consensus on echocardiographic recommendations, the medical and invasive management of HCM, the application of genetic testing and family screening, and exercise and reproductive recommendations in HCM. There were areas of variability in the definition and diagnostic criteria for HCM, cardiovascular magnetic resonance imaging recommendations, and assessment of sudden cardiac death (SCD) risk and prevention strategies. Due to the JCS\/JHFS guidelines being older, there are no recommendations on the use of cardiac myosin ATPase inhibitors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Contemporary guidelines for HCM achieve consensus across a broad range of criteria and recommendations concerning diagnosis and management. However, variations in the approach towards risk assessment for SCD exist between the guidelines. There are also more subtle differences concerning diagnostic criteria and the utility of late gadolinium enhancement for risk stratification, which will likely evolve as the evidence-base broadens.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjqcco\/qcae117","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T23:25:01Z","timestamp":1735687501000},"page":"919-933","source":"Crossref","is-referenced-by-count":11,"title":["Hypertrophic cardiomyopathy management: a systematic review of the clinical practice guidelines and recommendations"],"prefix":"10.1093","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1914-4149","authenticated-orcid":false,"given":"Mihir M","family":"Sanghvi","sequence":"first","affiliation":[{"name":"William Harvey Research Institute, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]},{"name":"NIHR Barts Biomedical Research Centre, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]},{"name":"Barts Heart Centre, Barts Health NHS Trust , West Smithfield, London EC1A 7BE ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eamon","family":"Dhall","sequence":"additional","affiliation":[{"name":"Newham University Hospital, Barts Health NHS Trust , Glen Road, London E13 8SL ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7825-8827","authenticated-orcid":false,"given":"C","family":"Anwar A. Chahal","sequence":"additional","affiliation":[{"name":"William Harvey Research Institute, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]},{"name":"Barts Heart Centre, Barts Health NHS Trust , West Smithfield, London EC1A 7BE ,","place":["UK"]},{"name":"Center for Inherited Cardiovascular Diseases, Department of Cardiology, WellSpan Health , 30 Monument Road, York, PA 17403 ,","place":["USA"]},{"name":"Department of Cardiovascular Medicine, Mayo Clinic , 200 First Street SW, Rochester, MN 55905 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constantinos","family":"O'Mahony","sequence":"additional","affiliation":[{"name":"Barts Heart Centre, Barts Health NHS Trust , West Smithfield, London EC1A 7BE ,","place":["UK"]},{"name":"UCL Institute of Cardiovascular Science, University College London , Gower Street, London WC1E 6BT ,","place":["UK"]},{"name":"NIHR University College London Hospitals Biomedical Research Centre, University College London , Gower Street, London WC1E 6BT ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saidi A","family":"Mohiddin","sequence":"additional","affiliation":[{"name":"William Harvey Research Institute, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]},{"name":"NIHR Barts Biomedical Research Centre, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]},{"name":"Barts Heart Centre, Barts Health NHS Trust , West Smithfield, London EC1A 7BE ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1966-1880","authenticated-orcid":false,"given":"Konstantinos","family":"Savvatis","sequence":"additional","affiliation":[{"name":"William Harvey Research Institute, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]},{"name":"NIHR Barts Biomedical Research Centre, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]},{"name":"Barts Heart Centre, Barts Health NHS Trust , West Smithfield, London EC1A 7BE ,","place":["UK"]},{"name":"UCL Institute of Cardiovascular Science, University College London , Gower Street, London WC1E 6BT ,","place":["UK"]},{"name":"NIHR University College London Hospitals Biomedical Research Centre, University College London , Gower Street, London WC1E 6BT ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9692-6616","authenticated-orcid":false,"given":"Fabrizio","family":"Ricci","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Imaging and Clinical Sciences, \u201cG. d'Annunzio\u201d University of Chieti-Pescara , Via dei Vestini 33, 66100 Chieti ,","place":["Italy"]},{"name":"University Cardiology Division, SS Annunziata Polyclinic University Hospital , Via dei Vestini 5, 66100 Chieti ,","place":["Italy"]},{"name":"Institute for Advanced Biomedical Technologies, \u201cG. d'Annunzio\u201d University of Chieti-Pescara , 66100 Chieti ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4176-2947","authenticated-orcid":false,"given":"Patricia B","family":"Munroe","sequence":"additional","affiliation":[{"name":"William Harvey Research Institute, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]},{"name":"NIHR Barts Biomedical Research Centre, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4622-5160","authenticated-orcid":false,"given":"Steffen E","family":"Petersen","sequence":"additional","affiliation":[{"name":"William Harvey Research Institute, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]},{"name":"NIHR Barts Biomedical Research Centre, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]},{"name":"Barts Heart Centre, Barts Health NHS Trust , West Smithfield, London EC1A 7BE ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5095-1611","authenticated-orcid":false,"given":"Nay","family":"Aung","sequence":"additional","affiliation":[{"name":"William Harvey Research Institute, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]},{"name":"NIHR Barts Biomedical Research Centre, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ ,","place":["UK"]},{"name":"Barts Heart Centre, Barts Health NHS Trust , West Smithfield, London EC1A 7BE ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5903-4454","authenticated-orcid":false,"given":"Mohammed 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