{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:35:04Z","timestamp":1790037304718,"version":"4.0.1"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T00:00:00Z","timestamp":1750377600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100005630","name":"French Society of Cardiology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005630","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Caisse Nationale d\u2019Assurance Maladie"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Acute heart failure (AHF) represents a major cause of morbi-mortality. In the last decade, the management of HF has changed, but up-to-date real-life data are scarce. The aim of our study was to describe contemporary data about AHF patients\u2019 medical pathway, management and to identify predictors of in-hospital outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>OFICA2 is a French prospective multicenter cohort led from March to April 2021 in 80 participating centres. In-hospital outcomes were defined as a composite of all-cause death, cardiogenic shock or transfer to intensive care unit. A total of 1513 consecutive patients (mean age 76 years, 61% male) hospitalized for AHF were included. One in five patients was not admitted in cardiology wards. A triggering factor was identified in 70% of cases, mostly supraventricular arrhythmia (21%). Median hospital stay was 11 days, and in-hospital mortality was 4.6%. Predictive factors of worse outcomes were a younger age, an initial acute coronary syndrome, a ventricular arrhythmia, a left ventricular ejection fraction (LVEF) \u2264 40%, a lower systolic blood pressure, a worse kidney function, and a higher C-reactive protein level on admission. At discharge, 61% of patients had an appointment scheduled with a cardiologist, 1 out of 4 patients with LVEF \u2264 40% had a combination of beta-blocker, renin-angiotensin system blocker and mineralocorticoid receptor antagonist, while 12% had no HF medication.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This comprehensive survey about patients hospitalized with AHF emphasizes HF care pathway, medical therapies and follow-up as weak spots. Filling these gaps might improve patients\u2019 management and prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjqcco\/qcaf044","type":"journal-article","created":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T07:59:12Z","timestamp":1750319952000},"page":"287-295","source":"Crossref","is-referenced-by-count":2,"title":["Current epidemiology and management of acute heart failure: the multicenter prospective OFICA2 cohort"],"prefix":"10.1093","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6434-2873","authenticated-orcid":false,"given":"Benjamin","family":"Alos","sequence":"first","affiliation":[{"name":"Cardiology Department, Clinical Investigation Center (INSERM 1402), University Hospital of Poitiers , 2, Rue de la Mil\u00e9trie Poitiers 86000 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