{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T01:22:53Z","timestamp":1794360173712,"version":"4.9.0"},"reference-count":73,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T00:00:00Z","timestamp":1756080000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union\u2019s Horizon","award":["847770"],"award-info":[{"award-number":["847770"]}]},{"name":"European Union\u2019s Horizon","award":["648131"],"award-info":[{"award-number":["648131"]}]},{"name":"European Union\u2019s Horizon","award":["101095480"],"award-info":[{"award-number":["101095480"]}]},{"DOI":"10.13039\/100012774","name":"Innovation Fund Denmark","doi-asserted-by":"publisher","award":["12-1352259"],"award-info":[{"award-number":["12-1352259"]}],"id":[{"id":"10.13039\/100012774","id-type":"DOI","asserted-by":"publisher"}]},{"name":"The Research Foundation for the Capital Region of Denmark"},{"DOI":"10.13039\/100007405","name":"Danish Heart Foundation","doi-asserted-by":"publisher","award":["11-04-R83-A3363-22625"],"award-info":[{"award-number":["11-04-R83-A3363-22625"]}],"id":[{"id":"10.13039\/100007405","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Aalborg University Talent Management Programme"},{"DOI":"10.13039\/100010447","name":"German Center for Cardiovascular Research","doi-asserted-by":"publisher","award":["81Z1710103"],"award-info":[{"award-number":["81Z1710103"]}],"id":[{"id":"10.13039\/100010447","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010447","name":"German Center for Cardiovascular Research","doi-asserted-by":"publisher","award":["81Z0710114"],"award-info":[{"award-number":["81Z0710114"]}],"id":[{"id":"10.13039\/100010447","id-type":"DOI","asserted-by":"publisher"}]},{"name":"German Ministry of Research and Education","award":["BMBF 01ZX1408A"],"award-info":[{"award-number":["BMBF 01ZX1408A"]}]},{"name":"ERACoSysMed3","award":["031L0239"],"award-info":[{"award-number":["031L0239"]}]},{"DOI":"10.13039\/501100005971","name":"German Heart Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005971","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Due to the ageing population in Europe, a significant increase in the incidence of atrial fibrillation (AF) is anticipated. This is predicted to have a detrimental impact on public health costs, particularly among the elderly, because of an increased number of stroke cases. Early detection of AF is crucial for initiating treatment with oral anticoagulants (OACs) to reduce the risk of stroke. This study aims to assess the cost-effectiveness of implementing AF screening programmes in eight European countries: Denmark, Germany, Ireland, Italy, the Netherlands, Serbia, Spain, and Sweden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>The analysis concerned invitation to AF population screening for 75-year-olds. A Markov cohort model was used, considering the prevalence of AF, screening yield, the use of different OACs, estimated clinical events, mortality, quality of life and costs. The model used country-specific parameters to produce specific cost-effectiveness estimates. Probabilistic sensitivity analyses were conducted to assess the impact of parametric uncertainties on the results. Inviting 75-year-olds to AF screening proved to be cost-effective across all eight countries analysed. In all countries, the strategy was dominant, meaning that quality-adjusted life-years were gained at lower costs. The time to financial break-even ranged from 6 to 14\u2005years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study indicates that population-based AF screening of 75-year-olds is a cost-effective strategy across eight European countries, meaning that adoption of such a strategy has the potential to make healthcare systems in these countries more efficient. The heterogeneity among European countries suggests that AF screening programmes may need to be tailored to the specific healthcare systems and conditions of each nation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjqcco\/qcaf099","type":"journal-article","created":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T11:38:30Z","timestamp":1755949110000},"page":"83-92","source":"Crossref","is-referenced-by-count":7,"title":["Cost-effectiveness of atrial fibrillation screening programmes across European nations"],"prefix":"10.1093","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0537-3319","authenticated-orcid":false,"given":"Lars","family":"Bernfort","sequence":"first","affiliation":[{"name":"Department of Health, Medicine and Caring Sciences, Link\u00f6ping University , Campus US, Link\u00f6ping 581 83 ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4988-6346","authenticated-orcid":false,"given":"Johan","family":"Lyth","sequence":"additional","affiliation":[{"name":"Department of Health, Medicine and Caring Sciences, Link\u00f6ping University , Campus US, Link\u00f6ping 581 83 ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1593-7379","authenticated-orcid":false,"given":"Kajsa","family":"Appelberg","sequence":"additional","affiliation":[{"name":"Department of Health, Medicine and Caring Sciences, Link\u00f6ping University , Campus US, Link\u00f6ping 581 83 ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9820-4815","authenticated-orcid":false,"given":"Giuseppe","family":"Boriani","sequence":"additional","affiliation":[{"name":"Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena , 411 24 Modena ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3174-7022","authenticated-orcid":false,"given":"Claire M","family":"Buckley","sequence":"additional","affiliation":[{"name":"School of Public Health, University College Cork , T12K8AF Cork ,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9687-0857","authenticated-orcid":false,"given":"S\u00f8ren Z\u00f6ga","family":"Diederichsen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The Heart Centre, Copenhagen University Hospital\u2014Rigshospitalet , 2200 Copenhagen ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7931-8941","authenticated-orcid":false,"given":"Michaela","family":"Eklund","sequence":"additional","affiliation":[{"name":"Department of Health, Medicine and Caring Sciences, Link\u00f6ping University , Campus US, Link\u00f6ping 581 83 ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9519-6258","authenticated-orcid":false,"given":"Daniel","family":"Engler","sequence":"additional","affiliation":[{"name":"Department of General and Interventional Cardiology, The University Medical Center Hamburg-Eppendorf , 202 51 Hamburg ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3809-2911","authenticated-orcid":false,"given":"Ben","family":"Freedman","sequence":"additional","affiliation":[{"name":"Heart Research Institute, Charles Perkins Centre and Faculty of Medicine and Health, The University of Sydney , NSW 2042 Sydney ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6285-6902","authenticated-orcid":false,"given":"Tatjana S","family":"Potpara","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Belgrade , 11000 Belgrade ,","place":["Serbia"]},{"name":"Department for Intensive Arrhythmia Care, Cardiology Clinic, Clinical Center of Serbia , 11000 Belgrade ,","place":["Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7170-9509","authenticated-orcid":false,"given":"Renate B","family":"Schnabel","sequence":"additional","affiliation":[{"name":"Department of General and Interventional Cardiology, The University Medical Center Hamburg-Eppendorf , 202 51 Hamburg 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