{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:37:38Z","timestamp":1777491458490,"version":"3.51.4"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T00:00:00Z","timestamp":1581033600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007605","name":"Aarhus University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007605","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007405","name":"Danish Heart Foundation","doi-asserted-by":"publisher","award":["16-R107-A6771-22001"],"award-info":[{"award-number":["16-R107-A6771-22001"]}],"id":[{"id":"10.13039\/100007405","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003554","name":"Lundbeck Foundation","doi-asserted-by":"publisher","award":["R184-2014-2478"],"award-info":[{"award-number":["R184-2014-2478"]}],"id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010371","name":"Raimond og Dagmar Ringg\u00e5rd-Bohns Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010371","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006197","name":"Fonden til L\u00e6gevidenskabens Fremme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006197","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Helge Peetz og Verner Peetz og hustru Vilma Peetz Legat Fond"},{"DOI":"10.13039\/501100008214","name":"K\u00f8bmand Sven Hansen og Hustru Ina Hansens Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008214","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ingeni\u00f8r August Frederik Wedell Erichsens Legat Fond"},{"name":"Handelsgartner Ove William Buhl Olesen og \u00e6gtef\u00e6lle fru Edith Buhl Olesens Mindelegat Fond"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Aortic valve repair procedures for the treatment of isolated aortic valve insufficiency may be improved by stabilizing the functional aortic annulus using a double annuloplasty ring at the aortic annulus and sinotubular junction (STJ). The objective of this study was to compare the geometrical changes and aortic root stress distribution when using a single subvalvular ring and a double sub- and supravalvular ring in vivo.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Both the single- and double-ring procedures were performed successively in nine 80-kg pigs. Measurements were performed intraoperatively using sonomicrometry crystals in the aortic root to evaluate geometrical changes and annular and STJ force transducers measuring the segmental radial stress distribution.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The total force in the STJ was significantly reduced after the double-ring procedure from 1.7\u2009\u00b1\u20090.6 to 0.04\u2009\u00b1\u20091.1\u2009N (P\u2009=\u20090.001). The double-ring procedure significantly reduced the STJ area from 234.8\u2009\u00b1\u200937.6 to 147.5\u2009\u00b1\u200931.8\u2009mm2 (P\u2009=\u20090.001) and expansibility from 17\u2009\u00b1\u20096% to 8\u2009\u00b1\u20093% (P\u2009=\u20090.001). With the single-ring procedure, the STJ shape was circular but became more oval with the double-ring procedure. The double-ring procedure did not affect stress distribution or geometry in the aortic annulus.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>The double-ring procedure stabilized the whole aortic root by reducing radial stress distribution in the STJ more efficiently than the single-ring procedure. Both area and expansibility were reduced with the double-ring procedure. These results confirm the importance of addressing the entire functional aortic annulus for optimal aortic valve repair procedures.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezaa001","type":"journal-article","created":{"date-parts":[[2020,1,8]],"date-time":"2020-01-08T12:09:07Z","timestamp":1578485347000},"page":"1210-1217","source":"Crossref","is-referenced-by-count":8,"title":["Altered stresses and dynamics after single and double annuloplasty ring for aortic valve repair"],"prefix":"10.1093","volume":"57","author":[{"given":"Leila Louise","family":"Benhassen","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark"},{"name":"Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2174-4557","authenticated-orcid":false,"given":"Jacob Hesselby","family":"Hedensted","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark"},{"name":"Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona","family":"Sharghbin","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark"},{"name":"Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2352-853X","authenticated-orcid":false,"given":"S\u00f8ren Nielsen","family":"Skov","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark"},{"name":"Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2938-8195","authenticated-orcid":false,"given":"Lisa","family":"Carlson Hanse","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark"},{"name":"Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4772-4319","authenticated-orcid":false,"given":"Marcell Juan","family":"Tj\u00f8rnild","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark"},{"name":"Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5832-5460","authenticated-orcid":false,"given":"Tommy","family":"Bechsgaard","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark"},{"name":"Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark"},{"name":"Department of Engineering, Faculty of Science and Technology, Aarhus University, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana Mathilde","family":"Ropcke","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark"},{"name":"Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sten 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