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By presenting 3 such cases, we highlight that pneumomediastinum can complicate the course of a severe coronavirus disease 2019 infection but emphasize that conservative management is the first-line method of treatment, with gradual resorption of the air from the tissues. It is important to be alert to the development of pneumothorax, which will require drainage.<\/jats:p>","DOI":"10.1093\/ejcts\/ezaa222","type":"journal-article","created":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T11:25:46Z","timestamp":1590578746000},"page":"646-647","source":"Crossref","is-referenced-by-count":42,"title":["Pneumomediastinum in COVID-19 patients: a case series of a rare complication"],"prefix":"10.1093","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7060-246X","authenticated-orcid":false,"given":"Sara","family":"Volpi","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, Croydon University Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2146-0711","authenticated-orcid":false,"given":"Jason M","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Royal Papworth Hospital, Cambridge, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alishah","family":"Suleman","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, Croydon University Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahim Nadeem","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, Croydon University Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,8,5]]},"reference":[{"key":"2021013016552625300_ezaa222-B1","first-page":"S44","article-title":"Pneumomediastinum","volume":"7","author":"Kouritas","year":"2015","journal-title":"J Thorac Dis"},{"key":"2021013016552625300_ezaa222-B2","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/S1473-3099(20)30156-0","article-title":"COVID-19 with spontaneous pneumomediastinum","volume":"20","author":"Zhou","year":"2020","journal-title":"Lancet Infect Dis"},{"key":"2021013016552625300_ezaa222-B3","doi-asserted-by":"crossref","first-page":"627","DOI":"10.3348\/kjr.2020.0281","article-title":"Spontaneous pneumomediastinum: a probable unusual complication of coronavirus disease 2019 (COVID-19) pneumonia","volume":"21","author":"Wang","year":"2020","journal-title":"Korean J Radiol"},{"key":"2021013016552625300_ezaa222-B4","doi-asserted-by":"crossref","first-page":"541","DOI":"10.3348\/kjr.2020.0180","article-title":"Mediastinal emphysema, giant bulla, and pneumothorax developed during the course of COVID-19 pneumonia","volume":"21","author":"Sun","year":"2020","journal-title":"Korean J Radiol"},{"key":"2021013016552625300_ezaa222-B5","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1007\/s00134-004-2187-7","article-title":"Incidence, risk factors and outcome of barotrauma in mechanically ventilated patients","volume":"30","author":"Anzueto","year":"2004","journal-title":"Intensive Care Med"}],"container-title":["European Journal of Cardio-Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ejcts\/article-pdf\/58\/3\/646\/36155616\/ezaa222.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ejcts\/article-pdf\/58\/3\/646\/36155616\/ezaa222.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,30]],"date-time":"2021-01-30T16:56:42Z","timestamp":1612025802000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejcts\/article\/58\/3\/646\/5880814"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,5]]},"references-count":5,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2020,8,5]]},"published-print":{"date-parts":[[2020,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ejcts\/ezaa222","relation":{},"ISSN":["1010-7940","1873-734X"],"issn-type":[{"value":"1010-7940","type":"print"},{"value":"1873-734X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,9]]},"published":{"date-parts":[[2020,8,5]]}}}