{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T02:40:37Z","timestamp":1788576037819,"version":"build-2803163510"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2020,9,27]],"date-time":"2020-09-27T00:00:00Z","timestamp":1601164800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>OBJECTIVES<\/jats:title>\n                    <jats:p\/>\n                    <jats:p>In Japan, homograft and bovine jugular vein are available in very limited institutions for the reconstruction of the right ventricular outflow tract, and handmade expanded polytetrafluoroethylene (ePTFE)-valved conduits have been widely used instead. This study aimed to clarify the long-term outcomes and the durability of the ePTFE-valved conduits purely by narrowing down to those with large sizes to eliminate the influence of the body growth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Between January 2002 and December 2015, patients who underwent right ventricular outflow tract reconstruction in 34 Japanese institutions using ePTFE-valved conduits with a diameter of \u226518\u2009mm were included. All the valved conduits were made in the authors\u2019 institution and delivered to each participating institution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Overall, 502 patients were included. Early mortality was 1.4% and not related to conduit failure. The overall survival rate was 98.2% at 5\u2009years and 96.6% at 10\u2009years. Freedom from conduit explantation was 99.5% at 5\u2009years and 89.0% at 10\u2009years. Three patients (0.13 per 100 patient-years) developed infective endocarditis of the conduit, and only 1 patient required conduit removal. Pulmonary insufficiency was mild or less in 480 (96%) patients, and conduit stenosis was mild or less in 436 (88%) patients at the latest follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>By narrowing the analyses down to only ePTFE conduits with a large size, satisfactory long-term outcomes of these conduits with a fan-shaped valve and bulging sinuses were shown. These conduits would be among the optimal choices for right ventricular outflow tract reconstruction.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejcts\/ezaa240","type":"journal-article","created":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T23:17:34Z","timestamp":1593559054000},"page":"1274-1280","source":"Crossref","is-referenced-by-count":21,"title":["Long-term results of large-calibre expanded polytetrafluoroethylene-valved conduits with bulging sinuses"],"prefix":"10.1093","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9534-4580","authenticated-orcid":false,"given":"Shuhei","family":"Fujita","sequence":"first","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, Children\u2019s Medical Center, Kyoto Prefectural University of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2846-9161","authenticated-orcid":false,"given":"Masaaki","family":"Yamagishi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, Children\u2019s Medical Center, Kyoto Prefectural University of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takako","family":"Miyazaki","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, Children\u2019s Medical Center, Kyoto Prefectural University of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinobu","family":"Maeda","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, Children\u2019s Medical Center, Kyoto Prefectural University of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiichi","family":"Itatani","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, Children\u2019s Medical Center, Kyoto Prefectural University of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Asada","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, Children\u2019s Medical Center, Kyoto Prefectural University of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisayuki","family":"Hongu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, 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