{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:28:00Z","timestamp":1761845280362,"version":"3.37.3"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2021,2,4]],"date-time":"2021-02-04T00:00:00Z","timestamp":1612396800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Heisenberg-Professorship for Aortic Surgery of the German Research Foundation"},{"DOI":"10.13039\/100004807","name":"DFG","doi-asserted-by":"publisher","award":["278040814"],"award-info":[{"award-number":["278040814"]}],"id":[{"id":"10.13039\/100004807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Minimally invasive staged segmental artery (SA) coil- and plug embolization is a new method for paraplegia prevention associated with extensive aortic procedures. Near-infrared spectroscopy of the paraspinal collateral network (cnNIRS) has emerged as a non-invasive method for spinal cord monitoring. The aim of this study was to evaluate cnNIRS to guide minimally invasive SA occlusion.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>In a chronic large animal experiment, 18 juvenile pigs underwent two-stage minimally invasive staged SA coil- and plug embolization for complete SA occlusion. Coil-embolization was performed either by SA main stem occlusion (characteristic of pig anatomy) or separately for the left- and right SA. Lumbar cnNIRS was recorded during and after the procedure. Neurological status was assessed up to 3 days after complete SA occlusion.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Mean time from SA coil embolization to minimum cnNIRS values was 11\u2009\u00b1\u20095\u2009min with an average decrease from 101\u2009\u00b1\u20092% to 78\u2009\u00b1\u20098% of baseline (difference: \u221223\u2009\u00b1\u20099, P\u2009&amp;lt;\u20090.001). Lumbar cnNIRS demonstrated significant differences between left and right when SAs were occluded separately in all cases (\u22127\u2009\u00b1\u20094%, 1 min after first SA occlusion; P\u2009=\u20090.001). Permanent paraplegia occurred in 2 (11%) and any kind of neurological deficit\u2014temporary or permanent\u2014in 7 animals (39%). Association between lumbar cnNIRS and neurological outcome after minimally invasive staged SA coil- and plug embolization suggests positive correlation (R\u2009=\u20090.5, P\u2009=\u20090.052).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Lumbar cnNIRS independently reacts to unilateral SA occlusion. cnNIRS-guided SA occlusion is feasible and may become a useful adjunct facilitating adequate and complete vessel occlusion.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezab005","type":"journal-article","created":{"date-parts":[[2021,1,6]],"date-time":"2021-01-06T21:17:33Z","timestamp":1609967853000},"page":"48-55","source":"Crossref","is-referenced-by-count":4,"title":["Experimental near-infrared spectroscopy-guided minimally invasive segmental artery 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