{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T12:01:15Z","timestamp":1782216075341,"version":"3.54.5"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2021,2,6]],"date-time":"2021-02-06T00:00:00Z","timestamp":1612569600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"University of Verona and the University of Parma FFBR-MIUR-2017"},{"name":"FIL-2018"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,6,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>\u2002<\/jats:title>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Indications for and timing of pulmonary valve replacement (PVR) after tetralogy of Fallot repair are controversial. Among magnetic resonance imaging indices proposed to time valve replacement, a right ventricular (RV) end-diastolic volume index greater than 160\u2009ml\/m2 is often used. Recent evidence suggests that this value may still identify patients with irreversible RV dysfunction, thus hindering recovery. Our goal was to define, using intraoperative video kinematic evaluation, whether a relationship exists between timing of PVR and early functional recovery after surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Between November 2016 and November 2018, a total of 12 consecutive patients aged 27.1\u2009\u00b1\u200919.1\u2009years underwent PVR on average 22.2\u2009\u00b1\u200913.3\u2009years after tetralogy of Fallot repair. Mean RV end-diastolic volume evident on the magnetic resonance images was 136.9\u2009\u00b1\u200935.7\u2009ml\/m2. Intraoperative cardiac kinematics were assessed by video kinematic evaluation via a high-speed camera acquiring videos at 200 fps before and after valve replacement.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Patients presenting with RV end-diastolic volume &amp;lt;147\u2009ml\/m2 were significantly younger (11.2\u2009\u00b1\u20095.0 vs 38.4\u2009\u00b1\u200917.0; P\u2009=\u20090.005) and had a shorter time interval to valve replacement (11.0\u2009\u00b1\u20095.2 vs 30.1\u2009\u00b1\u200911.3; P\u2009=\u20090.03). The entire population showed a moderate correlation among energy expenditure, cardiac fatigue, perimeter of contraction and preoperative RV end-diastolic volume index. Both groups showed a reduction in all kinematic parameters after PVR, but those with end-diastolic volume &amp;gt;147\u2009ml\/m2 showed an unpredictable outcome.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Video kinematic evaluation provides insight into intraoperative RV recovery in patients with tetralogy of Fallot undergoing PVR. Accordingly, functional recovery can be expected in patients with preoperative end-diastolic volume &amp;lt;147\u2009ml\/m2.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezab026","type":"journal-article","created":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T20:13:53Z","timestamp":1611000833000},"page":"1329-1336","source":"Crossref","is-referenced-by-count":11,"title":["Right ventricular functional recovery depends on timing of pulmonary valve replacement in tetralogy of Fallot: a video kinematic study"],"prefix":"10.1093","volume":"59","author":[{"given":"Giacomo","family":"Rozzi","sequence":"first","affiliation":[{"name":"Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, Verona, Italy"},{"name":"Department of Medicine and Surgery, University of Parma, Parma, Italy"},{"name":"Departement of Molecular Cardiology, Humanitas Clinical and Research Center, IRCCS, Rozzano, 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